H. Lee Moffitt Cancer Center & Research Institute

Physician, Faculty, and Staff

Craig W. Stevens, MD, PhD

Craig W. Stevens, MD, PhD

Faculty Rank:

Senior Member

Titles:

  • Chair, Department of Radiation Oncology

Department/Program Affiliations:

  • Thoracic Oncology  
  • Radiation Oncology  
  • Experimental Therapeutics  

Primary Address:

H. Lee Moffitt Cancer Center &
Research Institute
12902 Magnolia Drive
Tampa, FL 33612

Consultation/Referral Phone:

(813) 745-8424

USF Affiliations/College Department:

  • Medicine / Oncologic Sciences
  • Medicine / Radiology
  • Medicine / Clinical Affairs

University Academic Rank:

Professor

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Craig W. Stevens, MD, PhD

Education & Training:

  • M.D., Northwestern University, 1988
  • Ph.D., Northwestern University, 1987 - Tumor Cell Biology
  • B.S., Massachusetts Institute of Technology, 1981 - Biology
  • Residency, Georgetown University Hospital, 1993 - Radiation Oncology
  • Internship, Georgetown University Hospital, 1989 - Medicine

General Board Certification / SubSpecialty:

  • Radiation Oncology

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Craig W. Stevens, MD, PhD

Research Interests:

1. Mesothelioma, lung cancer, radiation treatment planning for lung cancer, predicting tumor/normal tissue response to radiation, and DNA repair.



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Craig W. Stevens, MD, PhD

Publications:

  1. Barthel JS, Kucera ST, Lin JL, Hoffe SE, Strosberg JR, Ahmed I, Dilling TJ, Stevens CW. Does Barrett's esophagus respond to chemoradiation therapy for adenocarcinoma of the esophagus?. Gastrointest Endosc. 2010 Feb;71(2):235-240. Pubmedid: 20003971.   Pubmed ID: 20003971

  2. Faygelman V, Hunt D, Walker L, Mueller R, Demarco ML, Dilling T, Stevens C, Zhang G. Validation of Pinnacle treatment planning system for use with Novalis delivery unit. J Appl Clin Med Phys. 2010;11(3):3240. Pubmedid: 20717094.   Pubmed ID: 20717094

  3. Feygelman V, Zhang GG, Stevens CW. Initial dosimetric evaluation of SmartArc - a novel VMAT treatment planning module implemented in a multi-vendor delivery chain. J Appl Clin Med Phys. 2010;11(1):3169-. Pubmedid: 20160702.   Pubmed ID: 20160702

  4. Zhang G, Feygelman V, Stevens C, Li W, Leuthold S, Springett G, Hoffe S. Re-planning for compensator-based imrt with original compensators. Med Dosim. 2010 Mar;. Pubmedid: 20207532.   Pubmed ID: 20207532

  5. Zhang G, Huang TC, Feygelman V, Stevens C, Forster K. Generation of composite dose and biological effective dose (BED) over multiple treatment modalities and multistage planning using deformable image registration. Med Dosim. 2010;35(2):143-150. Pubmedid: 19931027.   Pubmed ID: 19931027

  6. Harris E, Stevens C. Personalized treatment approaches in radiation oncology: the future is now. Cancer Control. 2008 Apr;15(2):100-101. Pubmedid: 18488854.   Pubmed ID: 18488854

  7. Javedan K, Stevens C, Forster K. Compensator-based intensity-modulated radiation therapy for malignant pleural mesothelioma post extrapleural pneumonectomy. J Appl Clin Med Phys. 2008 Oct;9(4):2799-2799. Pubmedid: 19020484.   Pubmed ID: 19020484

  8. Torres-Roca J, Stevens C. Predicting response to clinical radiotherapy: past, present, and future directions. Cancer Control. 2008 Apr;15(2):151-156. Pubmedid: 18376382.   Pubmed ID: 18376382

  9. Zhang G, Huang T, Forster K, Lin K, Stevens C, Harris E, Guerrero T. Dose mapping: Validation in 4D dosimetry with measurements and application inradiotherapy follow-up evaluation. Comput Methods Programs Biomed. 2008 Apr;90(1):25-37. Pubmedid: 18178288.   Pubmed ID: 18178288

  10. Zhang G, Huang T, Guerrero T, Lin K, Stevens C, Starkschall G, Forster K. Use of three-dimensional (3D) optical flow method in mapping 3D anatomic structure and tumor contours across four-dimensional computed tomography data. J Appl Clin Med Phys. 2008 Feb;9(1):2738-2738. Pubmedid: 18449166.   Pubmed ID: 18449166

  11. Nelson C, Starkschall G, Balter P, Morice R, Stevens C, Chang J. Assessment of lung tumor motion and setup uncertainties using implanted fiducials. Int J Radiat Oncol Biol Phys. 2007 Mar;67(3):915-923. Pubmedid: 17293241.   Pubmed ID: 17293241

  12. Rice D, Smythe W, Liao Z, Guerrero T, Chang J, McAleer M, Jeter M, Correa A, Vaporciyan A, Liu H, Komaki R, Forster K, Stevens C. Dose-Dependent Pulmonary Toxicity After Postoperative Intensity-Modulated Radiotherapy for Malignant Pleural Mesothelioma. Int J Radiat Oncol Biol Phys. 2007 Oct;69(2):350-7. Pubmedid: 17467922.   Pubmed ID: 17467922

  13. Rice D, Stevens C, Correa A, Vaporciyan A, Tsao A, Forster K, Walsh G, Swisher S, Hofstetter W, Mehran R, Roth J, Liao Z, Smythe W. Outcomes after extrapleural pneumonectomy and intensity-modulated radiation therapy for malignant pleural mesothelioma. Ann Thorac Surg. 2007 Nov;84(5):1685-92. Pubmedid: 17954086.   Pubmed ID: 17954086

  14. Robinson LA, Ruckdeschel JC, Wagner H, Stevens CW. Treatment of non-small cell lung cancer-stage IIIA: ACCP evidence-based clinical practice guidelines (2nd edition). Chest. 2007 Sep;132(3 Suppl):243S-265S. Pubmedid: 17873172.   Pubmed ID: 17873172

  15. Chandra A, Guerrero T, Liu H, Tucker S, Liao Z, Wang X, Murshed H, Bonnen M, Garg A, Stevens C, Chang J, Jeter M, Mohan R, Cox J, Komaki R. Feasibility of using intensity-modulated radiotherapy to improve lung sparing in treatment planning for distal esophageal cancer. Radiother Oncol. 2005 Dec; 77(3):247-253. Pubmedid: 16298001.   Pubmed ID: 16298001

  16. Chang J, Komaki R, Sasaki R, Liao Z, Stevens C, Lu C, Fossella F, Allen PK, Cox J, Spitz M, Wu X. High mutagen sensitivity in peripheral blood lymphocytes predicts poor overall and disease-specific survival in patients with stage III non-small cell lung cancer treated with radiotherapy and chemotherapy. Clin Cancer Res. 2005 Apr;11(8):2894-2898. Pubmedid: 15837739.   Pubmed ID: 15837739

  17. Erasmus J, Truong M, Smythe W, Munden R, Marom E, Rice D, VaporciyanAA, Walsh G, Sabloff B, Broemeling L, Stevens C, Pisters K, Podoloff D, Macapinlac H. Integrated computed tomography-positron emission tomography in patients with potentially resectable malignant pleural mesothelioma: Staging implications. J Thorac Cardiovasc Surg. 2005 Jun;129(6):1364-1370. Pubmedid: 15942579.   Pubmed ID: 15942579

  18. Munden R, Erasmus J, Smythe W, Madewell J, Forster K, Stevens C. Radiation injury to the liver after intensity-modulated radiation therapy in patients with mesothelioma: an unusual CT appearance. Ajr Am J Roentgenol. 2005 Apr;184(4):1091-1095. Pubmedid: 15788578.   Pubmed ID: 15788578

  19. Munden R, Swisher S, Stevens C, Stewart D. Imaging of the patient with non-small cell lung cancer. Radiology. 2005 Dec;237(3):803-818. Pubmedid: 16251391.   Pubmed ID: 16251391

  20. Ragan D, Starkschall G, McNutt T, Kaus M, Guerrero T, Stevens C. Semiautomated four-dimensional computed tomography segmentation using deformable models. Med Phys. 2005 Jul;32(7):2254-2261. Pubmedid: 16121580.   Pubmed ID: 16121580

  21. Rice D, Erasmus J, Stevens C, Vaporciyan A, Wu J, Tsao A, Walsh G, Swisher S, Hofstetter W, Ordonez N, Smythe W. Extended surgical staging for potentially resectable malignant pleural mesothelioma. Ann Thorac Surg. 2005 Dec;80(6):1988-1993. Pubmedid: 16305830.   Pubmed ID: 16305830

  22. Stevens C, Forster K, Smythe W, Rice D. Radiotherapy for mesothelioma. Hematol Oncol Clin North Am. 2005 Dec;19(6):1099-1115. Pubmedid: 16325126.   Pubmed ID: 16325126

  23. Stevens C, Wong P, Rice D, Jeter M, Forster K, Zhu X. Treatment planning system evaluation for mesothelioma IMRT. Lung Cancer. 2005 Jul;49:S75-S81. Pubmedid: 15950806.   Pubmed ID: 15950806

  24. Zhang Z, Liao Z, Jin J, Ajani J, Chang J, Jeter M, Guerrero T, Stevens C, Swisher S, Ho L, Yao J, Allen P, Cox J, Komaki R. Dose-response relationship in locoregional control for patients with stage II-III esophageal cancer treated with concurrent chemotherapy and radiotherapy. Int J Radiat Oncol Biol Phys. 2005 Mar;61(3):656-664. Pubmedid: 15708243.   Pubmed ID: 15708243

  25. Zhu X, Prado K, Liu H, Guerrero T, Jeter M, Liao Z, Rice D, Forster K, Stevens C. Intensity-modulated radiation therapy for mesothelioma: impact of multileaf collimator leaf width and pencil beam size on planning quality and delivery efficiency. Int J Radiat Oncol Biol Phys. 2005 Aug;62(5):1525-1534. Pubmedid: 16029815.   Pubmed ID: 16029815

  26. Burnett S, Starkschalla G, Stevens C, Liao Z. A deformable-model approach to semi-automatic segmentation of CT images demonstrated by application to the spinal canal. Med Phys. 2004;31(2):251-263. Pubmedid: 15000611.   Pubmed ID: 15000611

  27. Butler L, Forster K, Stevens C, Bloch C, Liu H, Tucker S, Komaki R, Liao Z, Starkschall G. Dosimetric benefits of respiratory gating: a preliminary study. J Appl Clin Med Phys. 2004;5(1):16-24. Pubmedid: 15753930.   Pubmed ID: 15753930

  28. Cardenas A, Fontenot J, Forster K, Stevens C, Starkschall G. Quality assurance evaluation of delivery of respiratory-gated treatments. J Appl Clin Med Phys. 2004;5(3):55-61. Pubmedid: 15753939.   Pubmed ID: 15753939

  29. Evans S, Judy K, Dunphy I, Jenkins W, Nelson P, Collins R, Wileyto E, Jenkins K, Hahn S, Stevens C, Judkins A, Phillips P, Geoerger B, Koch C. Comparative measurements of hypoxia in human brain tumors using needle electrodes and EF5 binding. Cancer Res. 2004;64(5):1886-1892. Pubmedid: 14996753.   Pubmed ID: 14996753

  30. Ismail S, Buchholz T, Story M, Brock W, Stevens C. Radiosensitivity is predicted by DNA end-binding complex density, but not by nuclear levels of band components. Radiother Oncol. 2004;72(3):325-332. Pubmedid: 15450732.   Pubmed ID: 15450732

  31. Ismail S, Puppi M, Prithivirajsingh S, Munshi A, Raju U, Meyn R, BuchholzTA, Story M, Brock W, Milas L, Thames H, Stevens C. Predicting radiosensitivity using DNA end-binding complex analysis. Clin Cancer Res. 2004;10(4):1226-1234. Pubmedid: 14977819.   Pubmed ID: 14977819

  32. Jin J, Liao Z, Zhang Z, Ajani J, Swisher S, Chang J, Jeter M, Guerrero T, Stevens C, Vaporciyan A, Putnam J J, Walsh G, Smythe R, Roth J, Yao J, AllenP, Cox J, Komaki R. Induction chemotherapy improved outcomes of patients with resectable esophageal cancer who received chemoradiotherapy followed by surgery. Int J Radiat Oncol Biol Phys. 2004;60(2):427-436. Pubmedid: 15380576.   Pubmed ID: 15380576

  33. Koch N, Liu H, Starkschall G, Jacobson M, Forster K, Liao Z, Komaki R, Stevens C. Evaluation of internal lung motion for respiratory-gated radiotherapy using MRI: Part I--correlating internal lung motion with skin fiducial motion. Int J Radiat Oncol Biol Phys. 2004;60(5):1459-1472. Pubmedid: 15590177.   Pubmed ID: 15590177

  34. Liao Z, Zhang Z, Jin J, Ajani J, Swisher S, Stevens C, Ho L, Smythe R, Vaporciyan A, Putnam JB J, Walsh G, Roth J, Yao J, Allen P, Cox J, KomakiR. Esophagectomy after concurrent chemoradiotherapy improves locoregional control in clinical stage II or III esophageal cancer patients. Int J Radiat Oncol Biol Phys. 2004;60(5):1484-1493. Pubmedid: 15590179.   Pubmed ID: 15590179

  35. Liu H, Koch N, Starkschall G, Jacobson M, Forster K, Liao Z, Komaki R, Stevens C. Evaluation of internal lung motion for respiratory-gated radiotherapy using MRI: Part II-margin reduction of internal target volume. Int J Radiat Oncol Biol Phys. 2004;60(5):1473-1483. Pubmedid: 15590178.   Pubmed ID: 15590178

  36. Liu H, Wang X, Dong L, Wu Q, Liao Z, Stevens C, Guerrero T, Komaki R, Cox J, Mohan R. Feasibility of sparing lung and other thoracic structures with intensity-modulated radiotherapy for non-small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2004;58(4):1268-1279. Pubmedid: 15001272.   Pubmed ID: 15001272

  37. Prithivirajsingh S, Story M, Bergh S, Geara F, Ang K, Ismail S, Stevens CW, Buchholz T, Brock W. Accumulation of the common mitochondrial DNA deletion induced by ionizing radiation. Febs Lett. 2004;571(1-3):227-232. Pubmedid: 15280047.   Pubmed ID: 15280047

  38. Starkschall G, Forster K, Kitamura K, Cardenas A, Tucker S, Stevens C. Correlation of gross tumor volume excursion with potential benefits of respiratory gating. Int J Radiat Oncol Biol Phys. 2004;60(4):1291-1297. Pubmedid: 15519802.   Pubmed ID: 15519802

  39. Stevens C. Opioid research in amphibians: an alternative pain model yielding insights on the evolution of opioid receptors. Brain Res Brain Res Rev. 2004;46(2):204-215. Pubmedid: 15464208.   Pubmed ID: 15464208

  40. Ahamad A, Stevens C, Smythe W, Liao Z, Vaporciyan A, Rice D, Walsh G, Guerrero T, Chang J, Bell B, Komaki R, Forster K. Promising early local control of malignant pleural mesothelioma following postoperative intensity modulated radiotherapy (IMRT) to the chest. Cancer J. 2003;9(6):476-484. Pubmedid: 14740977.   Pubmed ID: 14740977

  41. Ahamad A, Stevens C, Smythe W, Vaporciyan A, Komaki R, Kelly J, Liao Z, Starkschall G, Forster K. Intensity-modulated radiation therapy: a novel approach to the management of malignant pleural mesothelioma. Int J Radiat Oncol Biol Phys. 2003;55(3):768-775. Pubmedid: 12573764.   Pubmed ID: 12573764

  42. Burd R, Lavorgna S, Daskalakis C, Wachsberger P, Wahl M, Biaglow J, Stevens C, Leeper D. Tumor oxygenation and acidification are increased in melanoma xenografts after exposure to hyperglycemia and meta-iodo-benzylguanidine. Radiat Res. 2003;159(3):328-335. Pubmedid: 12600235.   Pubmed ID: 12600235

  43. Cox J, Schechter N, Lee A, Forster K, Stevens C, Ang K, Komaki R, LiaoZ, Milas L. Uncertainties in physical and biological targeting with radiation therapy. Rays. 2003;28(3):211-215. Pubmedid: 15018309.   Pubmed ID: 15018309

  44. Forster K, Smythe W, Starkschall G, Liao Z, Takanaka T, Kelly J, Vaporciyan A, Ahamad A, Dong L, Salehpour M, Komaki R, Stevens C. Intensity-modulated radiotherapy following extrapleural pneumonectomy for the treatment of malignant mesothelioma: clinical implementation. Int J Radiat Oncol Biol Phys. 2003;55(3):606-616. Pubmedid: 12573747.   Pubmed ID: 12573747

  45. Frank S, Forster K, Stevens C, Cox J, Komaki R, Liao Z, Tucker S, WangX, Steadham R, Brooks C, Starkschall G. Treatment planning for lung cancer: traditional homogeneous point-dose prescription compared with heterogeneity-corrected dose-volume prescription. Int J Radiat Oncol Biol Phys. 2003;56(5):1308-1318. Pubmedid: 12873675.   Pubmed ID: 12873675

  46. Gopal R, Starkschall G, Tucker S, Cox J, Liao Z, Hanus M, Kelly J, Stevens C, Komaki R. Effects of radiotherapy and chemotherapy on lung function in patients with non-small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2003;56(1):114-120. Pubmedid: 12694829.   Pubmed ID: 12694829

  47. Kaplan B, Stevens C, Allen P, Liao Z, Komaki R. Outcomes and patterns of failure in bronchial carcinoid tumors. Int J Radiat Oncol Biol Phys. 2003;55(1):125-131. Pubmedid: 12504044.   Pubmed ID: 12504044

  48. Komaki R, Liao Z, Forster K, Lee H, Stevens C, Cox J. Target definition and contouring in carcinoma of the lung and esophagus. Rays. 2003;28(3):225-236. Pubmedid: 15018311.   Pubmed ID: 15018311

  49. Stevens C. A mouse isn't a rat, but what's the big deal? Lighten up. Lab Anim (Ny). 2003;32(9):17-18. Pubmedid: 15235654.   Pubmed ID: 15235654

  50. Koenig T, Munden R, Erasmus J, Sabloff B, Gladish G, Komaki R, Stevens CW. Radiation injury of the lung after three-dimensional conformal radiation therapy. Ajr Am J Roentgenol. 2002;178(6):1383-1388. Pubmedid: 12034601.   Pubmed ID: 12034601

  51. Nimura Y, Ismail SM, Kurimas A, Chen DJ, Stevens CW. DNA-PK and ATM are required for radiation-enhanced integration. Radiat Res. 2002 May;157(5):562-567. Pubmedid: 11966322.   Pubmed ID: 11966322

  52. Shaw A, Li Z, Thomas Z, Stevens CW. Assessment of tissue oxygen tension: comparison of dynamic fluorescence quenching and polarographic electrode technique. Crit Care. 2002 Feb;6(1):76-80. Pubmedid: 11940270.   Pubmed ID: 11940270

Craig W. Stevens, MD, PhD

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