H. Lee Moffitt Cancer Center & Research Institute

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David J. Drobes, PhD

David J. Drobes, PhD

Faculty Rank:

Senior Member

Titles:

Department/Program Affiliations:

  • Tobacco Research & Intervention
  • Health Outcomes & Behavior

Primary Address:

4115 E. Fowler Ave
Tampa, FL 33617

Office:

(813) 745-1751

USF Affiliations/College Department:

  • Medicine / Interdisciplinary Oncology / Health Outcomes & Behavior
  • Arts & Sciences / Psychology

University Academic Rank:

Professor

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David J. Drobes, PhD

Education & Training:

  • B.S., State University of New York at Albany, 1984 - Psychology
  • M.S., Purdue University, 1987 - Psychology
  • Ph.D., Purdue University, 1993 - Clinical Psychology

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David J. Drobes, PhD

Research Interests:

Dr. Drobes' research program encompasses a broad perspective toward addictive behaviors, with a primary focus on nicotine/tobacco dependence, alcohol abuse and dependence, and interactions between tobacco and alcohol. As a member of the Tobacco Research & Intervention Program, he uses various human laboratory experimental paradigms to examine genetic and environmental influences on tobacco and alcohol use. His current work is focused on craving among smokers and alcoholics, and on attempts to manipulate craving and other aspects of drug use motivation among smokers. By using brief interventions to address the cognitive underpinnings of addiction, Dr. Drobes and his collaborators/students are attempting to determine whether acute changes in motivation to quit smoking are associated with corresponding changes in reactivity to smoking-related cues and reductions in smoking behavior. A long-term goal of this work is to improve upon the efficacy and dissemination of existing clinical treatments for tobacco addiction and other forms of drug addiction.

Other areas of interest include behavioral genetic markers of risk for tobacco addiction, the understanding and measurement of tobacco 'craving,' and the relationship between alcohol-related expectancies and cue reactivity. These research areas each incorporate psychophysiological, subjective, and behavioral/cognitive indices. Research in Dr. Drobes' laboratory has been funded by the National Cancer Institute, the National Institute on Alcohol Abuse and Alcoholism, and the National Institute of Mental Health.

Clinical Interests:

smoking cessation, addiction treatment

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David J. Drobes, PhD

Publications:

  1. Connolly KM, Coffey SF, Baschnagel JS, Drobes DJ, Saladin ME. Evaluation of the Alcohol Craving Questionnaire-Now factor structures: application of a cue reactivity paradigm. Drug Alcohol Depend. 2009 Jul;103(1-2):84-91. Pubmedid: 19423243. Pmcid: PMC2751634.   Pubmed ID: 19423243

  2. Evans D, Drobes D. Nicotine self-medication of cognitive-attentional processing. Addict Biol. 2009 Jan;14(1):32-42. Pubmedid: 18855804.   Pubmed ID: 18855804

  3. Evans DE, Park JY, Maxfield N, Drobes DJ. Neurocognitive variation in smoking behavior and withdrawal: genetic and affective moderators. Genes Brain Behav. 2009 Feb;8(1):86-96. Pubmedid: 19220487.   Pubmed ID: 19220487

  4. Mason BJ, Light JM, Williams LD, Drobes DJ. Proof-of-concept human laboratory study for protracted abstinence in alcohol dependence: effects of gabapentin. Addict Biol. 2009 Jan;14(1):73-83. Pubmedid: 18855801. Pmcid: PMC2758315.   Pubmed ID: 18855801

  5. Baschnagel J, Coffey S, Schumacher J, Drobes D, Saladin M. Relationship between PTSD symptomatology and nicotine dependence severity in crime victims. Addict Behav. 2008 Nov;33(11):1441-1447. Pubmedid: 18442884.   Pubmed ID: 18442884

  6. Lopez E, Drobes D, Thompson J, Brandon T. Effects of a body image challenge on smoking motivation among college females. Health Psychol. 2008 May;27:S243-S251. Pubmedid: 18979977.   Pubmed ID: 18979977

  7. Mason BJ, Light JM, Escher T, Drobes DJ. Effect of positive and negative affective stimuli and beverage cues on measures of craving in non treatment-seeking alcoholics. Psychopharmacology (Berl). 2008 Sep;200(1):141-150. Pubmedid: 18604601. Pmcid: PMC2758314.   Pubmed ID: 18604601

  8. Rash CJ, Coffey SF, Baschnagel JS, Drobes DJ, Saladin ME. Psychometric properties of the IES-R in traumatized substance dependent individuals with and without PTSD. Addict Behav. 2008 Aug;33(8):1039-1047. Pubmedid: 18501524.   Pubmed ID: 18501524

  9. Drobes D, Elibero A, Evans D. Attentional bias for smoking and affective stimuli: a stroop task study. Psychol Addict Behav. 2006 Dec;20(4):490-495. Pubmedid: 17176185.   Pubmed ID: 17176185

  10. Hendricks P, Ditre J, Drobes D, Brandon T. The early time course of smoking withdrawal effects. Psychopharmacology (Berl). 2006 Aug;187(3):385-396. Pubmedid: 16752139.   Pubmed ID: 16752139

  11. Upadhyaya H, Drobes D, Wang W. Reactivity to in vivo smoking cues in older adolescent cigarette smokers. Nicotine Tob Res. 2006 Feb;8(1):135-140. Pubmedid: 16497607.   Pubmed ID: 16497607

  12. Colby S, Drobes D, West R. International advances in nicotine and tobacco research. Nicotine Tob Res. 2005;7(4):667-709. Pubmedid: 16085535.   Pubmed ID: 16085535

  13. Drobes D, Munafo M, Leigh F, Saladin M. A family smoking index to capture genetic influence in smoking: rationale and two validation studies. Nicotine Tob Res. 2005 Feb;7(1):41-46. Pubmedid: 15804676.   Pubmed ID: 15804676

  14. Thomas S, Drobes D, Deas D. Alcohol cue reactivity in alcohol-dependent adolescents. J Stud Alcohol. 2005 May;66(3):354-360. Pubmedid: 16047524.   Pubmed ID: 16047524

  15. Anton R, Drobes D, Voronin K, Durazo-Avizu R, Moak D. Naltrexone effects on alcohol consumption in a clinical laboratory paradigm: temporal effects of drinking. Psychopharmacology (Berl). 2004;173(1-2):32-40. Pubmedid: 14722705.   Pubmed ID: 14722705

  16. Carrigan M, Drobes D, Randall C. Attentional bias and drinking to cope with social anxiety. Psychol Addict Behav. 2004;18(4):374-380. Pubmedid: 15631610.   Pubmed ID: 15631610

  17. Drobes D, Anton R, Thomas S, Voronin K. Effects of naltrexone and nalmefene on subjective response to alcohol among non-treatment-seeking alcoholics and social drinkers. Alcohol Clin Exp Res. 2004;28(9):1362-1370. Pubmedid: 15365307.   Pubmed ID: 15365307

  18. Drobes D, Cousino Klein L. Research on nicotine and tobacco: A decade of progress. Nicotine Tob Res. 2004;6(4):695-741. Pubmedid: 15370167.   Pubmed ID: 15370167

  19. Thomas S, Drobes D, Voronin K, Anton R. Following alcohol consumption, nontreatment-seeking alcoholics report greater stimulation but similar sedation compared with social drinkers. J Stud Alcohol. 2004;65(3):330-335. Pubmedid: 15222589.   Pubmed ID: 15222589

  20. Upadhyaya H, Drobes D, Thomas S. Reactivity to smoking cues in adolescent cigarette smokers. Addict Behav. 2004;29(5):849-856. Pubmedid: 15219329.   Pubmed ID: 15219329

  21. Cuthbert BN, Lang PJ, Strauss C, Drobes D, Patrick CJ, Bradley MM. The psychophysiology of anxiety disorder: fear memory imagery. Psychophysiology. 2003 May;40(3):407-422. Pubmedid: 12946114.   Pubmed ID: 12946114

  22. Drobes D, Anton R, Thomas S, Voronin K. A clinical laboratory paradigm for evaluating medication effects on alcohol consumption: naltrexone and nalmefene. Neuropsychopharmacology. 2003;28(4):755-764. Pubmedid: 12655322.   Pubmed ID: 12655322

  23. Parrott D, Drobes D, Saladin M, Coffey S, Dansky B. Perpetration of partner violence: effects of cocaine and alcohol dependence and posttraumatic stress disorder. Addict Behav. 2003;28(9):1587-1602. Pubmedid: 14656547.   Pubmed ID: 14656547

  24. Saladin M, Drobes D, Coffey S, Dansky B, Brady K, Kilpatrick D. PTSD symptom severity as a predictor of cue-elicited drug craving in victims of violent crime. Addict Behav. 2003;28(9):1611-1629. Pubmedid: 14656549.   Pubmed ID: 14656549

  25. Coffey S, Saladin M, Drobes D, Brady K, Dansky B, Kilpatrick D. Trauma and substance cue reactivity in individuals with comorbid posttraumatic stress disorder and cocaine or alcohol dependence. Drug Alcohol Depend. 2002;65(2):115-127. Pubmedid: 11772473.   Pubmed ID: 11772473

  26. Drobes D. Cue reactivity in alcohol and tobacco dependence. Alcohol Clin Exp Res. 2002;26(12):1928-1929. Pubmedid: 12500123.   Pubmed ID: 12500123

  27. Saladin M, Drobes D, Coffey S, Libet J. The human startle reflex and alcohol cue reactivity: effects of early versus late abstinence. Psychol Addict Behav. 2002;16(2):98-105. Pubmedid: 12079261.   Pubmed ID: 12079261

  28. Drobes D, Miller E, Hillman C, Bradley M, Cuthbert B, Lang P. Food deprivation and emotional reactions to food cues: implications for eating disorders. Biol Psychol. 2001;57(1-3):153-177. Pubmedid: 11454438.   Pubmed ID: 11454438

  29. George M, Anton R, Bloomer C, Teneback C, Drobes D, Lorberbaum J, Nahas Z, Vincent D. Activation of prefrontal cortex and anterior thalamus in alcoholic subjects on exposure to alcohol-specific cues. Arch Gen Psychiatry. 2001;58(4):345-352. Pubmedid: 11296095.   Pubmed ID: 11296095

  30. Mann K, Agartz I, Harper C, Shoaf S, Rawlings R, Momenan R, Hommer D, Pfefferbaum A, Sullivan E, Anton R, Drobes D, George M, Bares R, Machulla HJ, Mundle G, Reimold M, Heinz A. Neuroimaging in alcoholism: ethanol and brain damage. Alcohol Clin Exp Res. 2001;25(5):104S-109S. Pubmedid: 11391058.   Pubmed ID: 11391058

  31. Drobes D, Anton R. Drinking in alcoholics following an alcohol challenge research protocol. J Stud Alcohol. 2000;61(2):220-224. Pubmedid: 10757131.   Pubmed ID: 10757131

  32. Geffken G, Zelikovsky N, Clark-Rudman J, Silverstein J, Drobes D. Poor metabolic control during menstruation and sexual abuse issues in an adolescent with diabetes. Br J Med Psychol. 2000;73(Pt 4):561-565. Pubmedid: 11140796.   Pubmed ID: 11140796

David J. Drobes, PhD

Below is a list of active grants where the faculty member is the Principal Investigator. Grants are sorted by sponsor and then sorted by start date, with the more recent grant shown first.

Drug/Cue Interactions in Alcohol-Tobacco Comorbidity

5 R01 AA011157-11
Sponsor: Nat Institutes of Health / NIAAA
Project Dates: August 1, 2002 to November 30, 2010
Annual Direct Cost: $194,662
Annual Total Cost: $320,822
Project Total: $1,566,743

Influence of Smoking Abstinence and Age on ERP Indices of Attentional Control

1 R21 DA024226-01A2
Sponsor: Nat Institutes of Health / NIDA
Project Dates: April 1, 2009 to March 31, 2011
Annual Direct Cost: $150,000
Annual Total Cost: $244,031
Project Total: $446,664

Varenicline Effects on Cue Reactivity and Smoking Reward/Reinforcement

IIR # GA3051LP
Sponsor: Pfizer, Inc.
Project Dates: February 1, 2008 to November 30, 2010
Annual Direct Cost: $24,000
Annual Total Cost: $30,000
Project Total: $274,206

Varenicline Effects on Cue Reactivity and Smoking Reward/Reinforcement

IIR # GA3051LP
Sponsor: Pfizer, Inc.
Project Dates: February 1, 2008 to November 30, 2010
Annual Direct Cost: $32,000
Annual Total Cost: $40,000
Project Total: $274,206

Reward Sensitivity and Incentive Salience in Cigarette Smokers (NO COST EXTENSION)

1255-104-00-A
Sponsor: Univ of South Florida / Nat Institutes of Health
Project Dates: February 15, 2008 to January 31, 2011

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