Donald A. Smith, MD

BOARD CERTIFICATION:
          •  Neurological Surgery

FELLOWSHIP:
          •  University of South Florida - Micro-Neurosurgery

RESIDENCY:
          •  University of Vermont - Neurosurgery
          •  St. Luke's Hospital - General Surgery

MEDICAL SCHOOL:
          •  University of Vermont - MD

• Moore S, Persons D, Sosman J, Bobadilla D, Bedell V, Smith D, Wolman S, Tuthill R, Moon J, Sondak V, Slovak M. Detection of Copy Number Alterations in Metastatic Melanoma by a DNA Fluorescence In situ Hybridization Probe Panel and Array Comparative Genomic Hybridization: A Southwest Oncology Group Study (S9431). Clin Cancer Res. 2008 May;14(10):2927-2935. Pubmedid: 18483359.


• Giuliano AR, Nielson CM, Flores R, Dunne EF, Abrahamsen M, Papenfuss MR, Markowitz LE, Smith D, Harris RB. The optimal anatomic sites for sampling heterosexual men for human papillomavirus (HPV) detection: the HPV detection in men study. J Infect Dis. 2007 Oct;196(8):1146-1152. Pubmedid: 17955432.


• Smith DM, Daniel KG, Wang Z, Guida WC, Chan TH, Dou QP. Docking studies and model development of tea polyphenol proteasome inhibitors: applications to rational drug design. Proteins. 2004 Jan;54(1):58-70. Pubmedid: 14705024.


• Lee JR, Dalton RR, Messina JL, Sharma MD, Smith DM, Burgess RE, Mazzella F, Antonia SJ, Mellor AL, Munn DH. Pattern of recruitment of immunoregulatory antigen-presenting cells in malignant melanoma. Lab Invest. 2003 Oct;83(10):1457-1466. Pubmedid: 14563947.


• Kazi A, Daniel KG, Smith DM, Kumar NB, Dou QP. Inhibition of the proteasome activity, a novel mechanism associated with the tumor cell apoptosis-inducing ability of genistein. Biochem Pharmacol. 2003 Sep;66(6):965-976. Pubmedid: 12963483.


• Tchieu J, Fana F, Fink J, Harper J, Nair T, Niedner R, Smith D, SteubeK, Tam T, Veretnik S, Wang D, Gribskov M. The PlantsP and PlantsT Functional Genomics Databases. Nucleic Acids Res. 2003 Jan;31(1):342-344. Pubmedid: 12520018.


• Kuhn D, Smith D, Pross S, Whiteside T, Dou Q. Overexpression of interleukin-2 receptor alpha in a human squamous cellcarcinoma of the head and neck cell line is associated with increasedproliferation, drug resistance, and transforming ability. J Cell Biochem. 2003;89:824-836. Pubmedid: 12858347.


• Smith DM, Kazi A, Smith L, Long TE, Heldreth B, Turos E, Dou QP. A novel beta-lactam antibiotic activates tumor cell apoptotic program by inducing DNA damage. Mol Pharmacol. 2002 Jun;61(6):1348-1358. Pubmedid: 12021396.


• Herman G, Kelley R, Pureza V, Smith D, Kopacz K, Pitt J, Sutphen R, Sheffield L, Metzenberg A. Characterization of mutations in 22 females with X-linked dominant chondrodysplasia punctata (Happle syndrome). Genet Med. 2002;4(6):434-438. Pubmedid: 12509714.


• Smith D, Wang Z, Kazi A, Li L, Chan T, Dou Q. Synthetic analogs of green tea polyphenols as proteasome inhibitors. Mol Med. 2002;8(7):382-392. Pubmedid: 12393936.


• Nam S, Smith D, Dou Q. Tannic acid potently inhibits tumor cell proteasome activity, increases p27 andBax expression, and induces G1 arrest and apoptosis. Cancer Epidemiol Biomarkers Prev. 2001;10(10):1083-1088. Pubmedid: 11588135.


• Smith D, Messina J, Perrott R, Berman C, Reintgen D, Cruse C, Glass F, DeConti R, Trotti A, Fenske N. Clinical approach to neuroendocrine carcinoma of the skin (Merkel cell carcinoma). Cancer Control. 2000;7(1):72-83. Pubmedid: 10740663.


• Smith D, Gao G, Zhang X, Wang G, Dou Q. Regulation of tumor cell apoptotic sensitivity during the cell cycle. Int J Mol Med. 2000;6(5):503-507. Pubmedid: 11029514.


• Nam S, Smith D, Dou Q. Ester bond-containing tea polyphenols potently inhibit proteasome activity in vitro and in vivo. J Biol Chem. 2000;276:13322-13330. Pubmedid: 11278274.


• Makoui A, Smith D, Evans A, Cahill D. Early aneurysm recurrence after technically satisfactory Guglielmi detachable coil therapy: is early surveillance needed? Case report. J Neurosurg. 2000;92(2):355-358. Pubmedid: 10659027.


• Kolles W, Pahura R, Busenbark K, Hubble J, Wilkinson S, Lary A, Tuite P, Sine E, Lazano A, Hauser R, Malapira T, Smith D, Tarsy D, Miyawaki E, Norregaard T, Kormos T, Olawow C. High frequency unilateral thalamic stimulation in the treatment of essential & parkinsonian tumor. Ann Neurol. 1997;292-299. Pubmedid: noPMID.


• Ransohoff J, Smith D. Surgical treatment of metastic brain tumors. Cancer Control. 1995;2(4):315-319. Pubmedid: 10862171.


• Smith D, Clarke L, Fiedler J. Use of a clinical MR scanner for imaging the rat brain. Brain Res Bull. 1993;31:115-120.


• Root A, Smith D, Pavan P. BB shots in the sella turcica. J Neuroimaging. 1993;3:198-199.


• Bosek V, Smith D, Cox C. Ketorolac or fentanyl to supplement local anesthesia?. J Clin Anesth. 1992;4(6):480-483.