H. Lee Moffitt Cancer Center & Research Institute

Imaging in Oncology

A Chest CT Abnormality in an Immunocompromised Patient

Jon E. Anderson, MD, and Evan W. Harris, MD
Radiology Service, H. Lee Moffitt Cancer Center & Research Institute


This regular feature will enhance your knowledge of imaging technology in
oncologic diagnosis, treatment, and evaluation.


Case Description:

A 42-year-old woman with stage IV breast carcinoma recently underwent high-dose chemotherapy with an autologous peripheral blood stem cell transplant. Her clinical course was complicated by pulmonary aspergillosis. Following discharge, intermittent fever and several episodes of hemoptysis occurred during her recovery. Computed tomography (CT) of the chest was obtained prior to and following discharge, and selected images and findings are demonstrated in Figs 1A-B.

Among the following, the best diagnosis for the lesion demonstrated by CT is:

  1. metastatic breast carcinoma
  2. primary neoplasm of the lung
  3. mycotic pulmonary artery aneurysm
  4. aspergilloma

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    Back to Cancer Control Journal Volume 4 Number 3


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