September / October 1998

Vol 5, No 5 CME Pretest

In this issue, the topic of high-dose therapy is addressed. First, answer the pretest questions below. After reading the articles, proceed with answering the CME posttest questions.

This Journal provides 4 hours of Category 1 Continuing Medical Education

Complimentary CME Credits

Physicans can earn up to 4 credit hours of Category 1 for the Physican's Recognition Award of the American Medical Association by reading the material in this issue and successfully answering the questions on the posttest at the end of this issue. Complete instructions are given on the posttest pages. Every successfully answered 10 questions will earn 1 credit hour. CME is presented by an unrestricted educational grant from Bristol-Myers Oncology Division.

Educational Objectives

After reading this issue, clinicians will be expected to:

• appreciate recent advances in techniques used and results from high-dose chemotherapy and stem-cell or marrow transplant,
  
• recognize the possibility of radiation-induced tumors in patients with breast cancer, and
  
• describe the use and side effects of lipid formulations of amphotericin for fungal infections in cancer patients.
  

This program was planned in accordance with ACCME Essentials.
Release Date: September 1, 1998 Expiration Date: September 1, 1999

Pretest

1. When high-dose therapy and stem-cell transplantation are discussed with breast cancer patients as treatment options, what expectation of mortality due to treatment is commonly presented?

a. 5%

b. 10%

c. 15%

d. 20%

2. The primary reason for failure of autologous bone marrow/stem-cell transplantation in patients with breast cancer is:

a. infection

b. treatment-related mortality

c. graft-vs-host disease

d. relapse

3. If the marrow of a patient with breast cancer is negative for tumor cells by immunocytochemistry, what is the probability of tumor contamination of the peripheral blood stem-cell product if it had been mobilized with chemotherapy and cytokines?

a. 10%

b. 20%

c. 50%

d. 60%