Roohi Ismail-Khan, MD

Dr. Ismail-Khan’s research interests include reducing or eliminating long-term side effects of chemotherapy to improve quality of life.  She is also focused on triple negative breast cancer; an aggressive disease that responds well to therapy, but often recurs and spreads.  The question why is a challenge that medical oncologists must answer.

• Yardley DA, Ismail-Khan RR, Melichar B, Lichinitser M, Munster PN, Klein PM, Cruickshank S, Miller KD, Lee MJ, Trepel JB. Randomized Phase II, Double-Blind, Placebo-Controlled Study of Exemestane With or Without Entinostat in Postmenopausal Women With Locally Recurrent or Metastatic Estrogen Receptor-Positive Breast Cancer Progressing on Treatment With a Nonsteroidal Aromata. J Clin Oncol. 2013 May. Pubmedid: 23650416.
• Donovan KA, Boyington AR, Ismail-Khan R, Wyman JF. Urinary symptoms in breast cancer: a systematic review. Cancer. 2012 Feb;118(3):582-593. Pubmedid: 21751193. Pmcid: PMC3193898.
• Munster PN, Moore AP, Ismail-Khan R, Cox CE, Lacevic M, Gross-King M, Xu P, Carter WB, Minton SE. Randomized trial using gonadotropin-releasing hormone agonist triptorelin for the preservation of ovarian function during (neo)adjuvant chemotherapy for breast cancer. J Clin Oncol. 2012 Feb;30(5):533-538. Pubmedid: 22231041. Pmcid: PMC3295555.
• Bardhan P, Bui MM, Minton S, Loftus L, Carter WB, Laronga C, Ismail-Khan R. HER2-positive male breast cancer with thyroid cancer: an institutional report and review of literature. Ann Clin Lab Sci. 2012;42(2):135-139. Pubmedid: 22585608.
• Munster PN, Thurn KT, Thomas S, Raha P, Lacevic M, Miller A, Melisko M, Ismail-Khan R, Rugo H, Moasser M, Minton SE. A phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancer. Br J Cancer. 2011 Jun;104(12):1828-1835. Pubmedid: 21559012. Pmcid: PMC3111195.
• Ismail-Khan R, Bui MM. A review of triple-negative breast cancer. Cancer Control. 2010 Jul;17(3):173-176. Pubmedid: 20664514.
• Simon GR, Extermann M, Chiappori A, Williams CC, Begum M, Kapoor R, Haura EB, Ismail-Khan R, Schell MJ, Antonia SJ, Bepler G. Phase 2 trial of docetaxel and gefitinib in the first-line treatment of patients with advanced nonsmall-cell lung cancer (NSCLC) who are 70 years of age or older. Cancer. 2008 May;112(9):2021-2029. Pubmedid: 18300255.
• Simon GR, Ismail-Khan R, Bepler G. Nuclear excision repair-based personalized therapy for non-small cell lung cancer: from hypothesis to reality. Int J Biochem Cell Biol. 2007;39(7-8):1318-1328. Pubmedid: 17600754. Pmcid: PMC3167070.
• Ismail-Khan R, Robinson L, Williams CC J, Garrett C, Bepler G, Simon G. Malignant pleural mesothelioma: a comprehensive review. Cancer Control. 2006 Oct;13(4):255-263. Pubmedid: 17075562.
• Khan MA, Andrews S, Ismail-Khan R, Munster PN, Brem S, King J, Reintgen DS, Sondak VK, Daud AI. Overall and progression-free survival in metastatic melanoma: analysis of a single-institution database. Cancer Control. 2006 Jul;13(3):211-217. Pubmedid: 16885917.