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Clinical Trial Search

43 Clinical Trials Found

Clinical Trial 21850

Phase 1/1b, Multicenter, Open-Label, Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects with Advanced KRASG12C Mutant Solid Tumors
Disease Site: Lung
PI: Pellini, Bruna

Clinical Trial 22196

A First in Human Dose Escalation and Cohort Expansion Study of DLL3-directed Chimeric Antigen Receptor T-cells in Subjects with Extensive Stage Small Cell Lung Cancer
Disease Site: Lung
PI: Chiappori, Alberto

Clinical Trial 20827

An Open-Label, Multi-Center Phase I/IIa Study Evaluating the Safety and Clinical Activity of Neoantigen Reactive T cells in Patients with Advanced Non-Small Cell Lung Cancer (CHIRON)
Disease Site: Lung, Non small cell lung cancer
PI: Creelan, Benjamin

Clinical Trial 21158

Disease Site: Lung
PI: Gray, Jhanelle

Clinical Trial 20530

Multicenter, Phase II, Neoadjuvant and Adjuvant Study of Alectinib, Entrectinib, or Vemurafenib Plus Cobimetinib in Patients with Stages I-III Non-Small Cell Lung Cancer with ALK, ROS1, NTRK, or BRAF V600E Molecular Alterations
Disease Site: Lung
PI: Saltos, Andreas

Clinical Trial 22380

Disease Site: Lung
PI: Chiappori, Alberto

Clinical Trial 20386

Targeting ODC as an Immunotherapeutic Target in STK11 (LKB1) Pathway-Deficient NSCLC
Disease Site: Lung
PI: Gray, Jhanelle

Clinical Trial 21626

A Phase 1, Open-Label, Multicenter Study to Assess Safety, Tolerability, PK, and Efficacy of MK-1084 as Monotherapy and in Combination with Pembrolizumab in Subjects with KRASG12C Mutant Advanced Solid Tumors
Disease Site: Lung
PI: Gray, Jhanelle

Clinical Trial 21986

A Phase 2, Multicenter, Randomized, Open-Label Study of DS-7300a, a B7-H3 Antibody Drug Conjugate (ADC), in Subjects with Pretreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC)
Disease Site: Lung
PI: Chiappori, Alberto

Clinical Trial 22305

Disease Site: Breast, Lung, Other Respiratory and Intrathoracic Organs
PI: Soyano Muller, Aixa

Clinical Trial 22685

Phase 1/1B, Multicenter, Open-Label, Study of RMC-9805 in Participants with Advanced KRASG12D-Mutant Solid Tumors
Disease Site: Any Site, Esophagus, Liver, Lung, Other Digestive Organ, Pancreas, Small Intestine, Stomach
PI: Kim, Dae Won

Clinical Trial 20178

An Open-Label Randomized Phase II Study of Combining Osimertinib with and without Ramucirumab in TKI-naïve EGFR-mutant Locally Advanced or Metastatic NSCLC
Disease Site: Lung, Non small cell lung cancer
PI: Saltos, Andreas