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The Blood and Marrow Transplant and Cellular Immunotherapy (BMT CI) Program at Moffitt Cancer Center is the largest and most active program of its kind in the Southeast. Committed to providing every aspect of treatment and supportive care in a single, convenient location, Moffitt is an established leader in the field of bone marrow transplantation (BMT) and chimeric antigen receptor or CAR T cell therapy. We are a National Marrow Donor Program (NMDP) transplant and collection center, and we are fully accredited by the Foundation for the Accreditation of Cellular Therapy (FACT), speaking to the unwavering dedication and expertise of our team.

Dr. Frederick Locke standing in front of his labLed by Dr. Frederick Locke, Moffitt's Blood and Marrow Transplant and Cellular Immunotherapy (BMT CI) Program serves patients with a number of hematological conditions, including leukemia, lymphoma, multiple myeloma, aplastic anemia, and myelodysplastic syndrome (MDS), myelofibrosis, sickle cell, as well as select solid tumors such as germ cell tumor (or testicular cancer.) After individually assessing each patient’s condition, our multispecialty team recommends the most appropriate transplant and cellular immunotherapy option.

We routinely perform:

  • Autologous and allogenic hematopoietic cell transplants
  • Myeloablative and reduced-intensity (RIC) / non-myeloablative (NMA) transplants
  • Peripheral blood stem cell and bone marrow transplants
  • Related haploidentical and mismatched unrelated donor transplants
  • CD19- and B cell maturation antigen (BCMA)-targeted CAR T cell therapy

As a core member of the BMT Clinical Trials Network (BMT CTN), SWOG, and in collaboration with industry sponsors, Moffitt offers an advanced program that hosts a number of transplant and CAR T as well as other cutting-edge cellular immunotherapy clinical trials, offering patients the opportunity to benefit from specialized techniques and technologies that aren't yet available elsewhere. To learn more about the clinical trials currently available at Moffitt, contact us at 813-745-6100 or 1-800-679-0775 (toll-free) or submit a clinical trials inquiry form.

As part of our commitment to comprehensive medicine, we offer a complete range of supportive care services as well, including identifying unrelated donors, medical management of post-transplant complications -- including graft-versus-host disease (GVHD) with extracorporeal photopheresis (ECP) -- as well as dietary counseling and specialty pharmacy services, all in a single, easy-to-access clinic.

Due to the specialization of our Blood and Marrow Transplant and Cellular Immunotherapy Program (BMT CI), we are able to achieve exceptional outcomes for our patients, and also offer transplantation and CAR T services for many patients with potential contraindications, such as advanced age. We are one of the only centers to offer transplantation for adults age 70 and older who are indicated for a bone marrow transplant (BMT).

Medically reviewed by Taiga Nishihori, MD

To refer a patient to Moffitt's Blood and Marrow Transplant and Cellular Immunotherapy Program for BMT or CAR T, complete our online form or contact a physician liaison for assistance or support. We prioritize short referral times and strive to respond to all referrals on the same business day that they are received.

2024 Cell Coast Conference

October 25-27, 2024 - St. Pete Beach, FL

Join us for an exclusive summit featuring updates and breakthroughs in research and treatment in the cell therapies space from global thought leaders. 


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