Testing Metformin for Oral Cancer Prevention

Metformin is in a class of drugs called biguanides. Metformin helps control the amount of glucose in the blood. It decreases the amount of glucose patients absorb from food and the amount of glucose made by the liver, as well as increases the body’s response to insulin, a natural substance that controls the amount of glucose in the blood.

The objective of clinical trial MCC 21940 is to help researchers determine the historical response to metformin intervention that can stop changes in the mouth related to pre-cancer growths in the mouth.

Dr. Christine Chung, chair of the Department of Head and Neck-Endocrine Oncology, is the principal investigator for this trial.

Click the MCC Trial 21940 to see the trial eligibility criteria.

If you'd like to refer a patient to Moffitt Cancer Center, complete our online form or contact a physician liaison for assistance. As part of our efforts to shorten referral times as much as possible, online referrals are typically responded to within 24 - 48 hours.