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Cholangiocarcinoma recurrence is possible after a patient completes an initial course of treatment and is found to be cancer-free (in remission) for a period of time. For this reason, many experts recommend a carefully planned follow-up program, including regular physical examinations, imaging scans and lab tests designed to monitor a patient’s recovery on an ongoing basis. Researchers continue to investigate possible ways to prevent bile cancer recurrence and progress is being made, but as of yet there are no widely recommended preventive measures.

Treatment for a cholangiocarcinoma recurrence may include surgery, chemotherapy or radiation therapy. The recommended approach can vary based on a number of factors, including the location of the cancer, the cancer’s response to the initial treatment and the patient’s overall health condition. Some patients with recurrent bile duct cancer may choose to participate in clinical trials of promising new treatments, such as:

  • New chemotherapy drugs and drug combinations
  • Stent placement with or without radiation therapy to relieve symptoms and enhance quality of life
  • New radiation treatment techniques, such as a combined approach that incorporates hyperthermia therapy, chemotherapy or radiosensitizers

Moffitt Cancer Center has a robust portfolio of clinical trials through which our patients can be among the first to benefit from innovative therapies for cholangiocarcinoma recurrence before those treatments are made available elsewhere. We are committed to remaining at the forefront of bile cancer research, and our extensive efforts have led to groundbreaking advances in its prevention, diagnosis, treatment and support. Our work has received national acclaim, including a Comprehensive Cancer Center designation from the National Cancer Institute, and we are the only cancer center based in Florida to have received this prestigious recognition.

If you have concerns about a cholangiocarcinoma recurrence, the experts at Moffitt can provide individualized advice and preventive strategies to help lower your risk, along with advanced diagnostic tests to ensure early detection and prompt treatment in the event that unusual changes occur. Call 1-888-663-3488 or complete a new patient registration form online. We do not require referrals.