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Shaffer  Mok

Shaffer Mok, MD, MBS

4.9 (53)

Specialty: Gastroenterology

Program: Gastrointestinal Oncology

Language(s): English

  • Overview

    Dr. Mok received his MD from Ross University School of Medicine. He completed an Internal Medicine Residency at Cooper Medical School of Rowan University, where he also served as Chief Resident, followed by a Gastroenterology Fellowship at the same institution, where he also served as Chief Fellow. He completed additional fellowship training in Advanced Endoscopy at Geisinger Medical Center in Danville, Pennsylvania and served as an Assistant Professor at the Case Western Reserve University School of Medicine. Dr. Mok is currently the Program Director for Moffitt's Advanced Endoscopy Fellowship. Dr. Mok’s clinical interests include therapeutic endoscopic ultrasound/ERCP and adjunct/alternative therapy for cancer. He also has an interest in endoscopic submucosal dissection, resection and full thickness resection for the treatment of foregut malignancy. His research interests include endoscopic ultrasound guided therapeutics, adjunct/alternative therapy for GI cancers, and optimizing endoscopic tissue acquisition. 

    Education & Training


    • Cooper University Hospital - Gastroenterology and Liver Disease
    • Geisinger Health Systems - Interventional Endoscopy Fellow
    • Institute of Functional Medicine -


    • Cooper University Hospital -

    Medical School:

    • Ross University of School of Medicine - MD
  • Participating Trials

    Clinical Trial 21908
    A Systematic Review of Supplements Applicable in Treatment of Pancreatic Adenocarcinoma with Action on the mTOR Complex
    Condition: Gastrointestinal Tumor
    Status: Open

    Clinical Trial 22156
    The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics
    Condition: Gastrointestinal Tumor
    Status: Open

    If you believe you are eligible for one of these trials or studies, please call
    813-745-6100 or toll-free 1-800-679-0775.

  • Publications

    • Jeong D, Morse B, Polk SL, Chen DT, Li J, Hodul P, Centeno BA, Costello J, Jiang K, Machado S, El Naqa I, Farah PT, Huynh T, Raghunand N, Mok S, Dam A, Malafa M, Qayyum A, Fleming JB, Permuth JB. Pancreatic Cyst Size Measurement on Magnetic Resonance Imaging Compared to Pathology. Cancers (Basel). 2024 Jan.16(1). Pubmedid: 38201633. Pmcid: PMC10778543.
    • Nikiforova MN, Wald AI, Spagnolo DM, Melan MA, Grupillo M, Lai YT, Brand RE, O'Broin-Lennon AM, McGrath K, Park WG, Pfau PR, Polanco PM, Kubiliun N, DeWitt J, Easler JJ, Dam A, Mok SR, Wallace MB, Kumbhari V, Boone BA, Marsh W, Thakkar S, Fairley KJ, Afghani E, Bhat Y, Ramrakhiani S, Nasr J, Skef W, Thiruvengadam NR, Khalid A, Fasanella K, Chennat J, Das R, Singh H, Sarkaria S, Slivka A, Gabbert C, Sawas T, Tielleman T, Vanderveldt HD, Tavakkoli A, Smith LM, Smith K, Bell PD, Hruban RH, Paniccia A, Zureikat A, Lee KK, Ongchin M, Zeh H, Minter R, He J, Nikiforov YE, Singhi AD. A Combined DNA/RNA-based Next-Generation Sequencing Platform to Improve the Classification of Pancreatic Cysts and Early Detection of Pancreatic Cancer Arising From Pancreatic Cysts. Ann Surg. 2023 Oct.278(4):e789-e797. Pubmedid: 37212422. Pmcid: PMC10481930.
    • Jiang J, Chao WL, Cao T, Culp S, Napoléon B, El-Dika S, Machicado JD, Pannala R, Mok S, Luthra AK, Akshintala VS, Muniraj T, Krishna SG. Improving Pancreatic Cyst Management: Artificial Intelligence-Powered Prediction of Advanced Neoplasms through Endoscopic Ultrasound-Guided Confocal Endomicroscopy. Biomimetics (Basel). 2023 Oct.8(6). Pubmedid: 37887627. Pmcid: PMC10604893.
    • Karb D, DeLozier S, Raad D, Dumot J, Mok S. Effect of Delayed Endoscopy Protocol on Timing and Safety of Endoscopy for Foreign Body Ingestion and Esophageal Food Impaction. J Clin Gastroenterol. 2023 Oct.57(9):890-894. Pubmedid: 36730739.
    • Mok SRS. Top 10 tips for foreign body and food impactions. Gastrointest Endosc. 2023 Nov.98(5):830-833. Pubmedid: 37481002.
    • Zhang N, Wang F, Zhu L, Chang R, Mok SRS, Peixoto RD, Tang W, Chen Z. Molecular mechanism of the miR-7/BCL2L1/P53 signaling axis regulating the progression of hepatocellular carcinoma. Ann Transl Med. 2023 Jan.11(1):12. Pubmedid: 36760243. Pmcid: PMC9906214.
    • Park MA, Zaw T, Yoder SJ, Gomez M, Genilo-Delgado M, Basinski T, Katende E, Dam A, Mok SRS, Monteiro A, Mohammadi A, Jeong DK, Jiang K, Centeno BA, Hodul P, Malafa M, Fleming J, Chen DT, Mo Q, Teer JK, Permuth JB. A pilot study to evaluate tissue- and plasma-based DNA driver mutations in a cohort of patients with pancreatic intraductal papillary mucinous neoplasms. G3 (Bethesda). 2023 Feb.13(2). Pubmedid: 36454217. Pmcid: PMC9911050.
    • Li J, Zhang D, Liu H, Wang D, Pan C, Biachi de Castria T, Mok SRS, Zhou Z, Yan C. Identification of potential prognostic biomarkers among gene models for coiled-coil domain-containing family members in hepatocellular carcinoma elucidates their influence on the hypoxia pathway and immune microenvironment. J Gastrointest Oncol. 2023 Dec.14(6):2559-2573. Pubmedid: 38196528. Pmcid: PMC10772702.
    • Zhou Y, Gu H, Shao B, Zhang S, Pall H, Peixoto RD, Mok SRS, Zhu G. Glycolysis-related gene dihydrolipoamide acetyltransferase promotes poor prognosis in hepatocellular carcinoma through the Wnt/β-catenin and PI3K/Akt signaling pathways. Ann Transl Med. 2022 Nov.10(22):1240. Pubmedid: 36544660. Pmcid: PMC9761179.
    • Dwyer S, Mok S. Endoscopic full-thickness resection of well-differentiated T2 neuroendocrine tumors in the duodenal bulb: a case series. VideoGIE. 2022 May.7(5):196-199. Pubmedid: 35585893. Pmcid: PMC9108274.
    • Smith ZL, Satyavada S, Simons-Linares R, Mok SRS, Martinez Moreno B, Aparicio JR, Chahal P. Intracystic Glucose and Carcinoembryonic Antigen in Differentiating Histologically Confirmed Pancreatic Mucinous Neoplastic Cysts. Am J Gastroenterol. 2022 Mar.117(3):478-485. Pubmedid: 35034045.
    • Hue JJ, Katayama ES, Markt SC, Elshami M, Saltzman J, Bajor D, Hosmer A, Mok S, Dumot J, Ammori JB, Rothermel LD, Hardacre JM, Winter JM, Ocuin LM. A nationwide analysis of pancreatic cancer trial enrollment reveals disparities and participation problems. Surgery. 2022 Jul.172(1):257-264. Pubmedid: 34839935.
    • Alabd A, Mok SRS. Multilevel stenting of malignant colonic obstructions from multilevel breast cancer colonic metastasis. VideoGIE. 2022 Apr.7(4):152-153. Pubmedid: 35937200. Pmcid: PMC9347000.
    • Trager RJ, Mok SRS, Schlick KJ, Perez JA, Dusek JA. Association between radicular low back pain and constipation: a retrospective cohort study using a real-world national database. Pain Rep. 2021 Aug.6(3):e954. Pubmedid: 34476303. Pmcid: PMC8397289.
    • Mohan S, Mok S, Judge T. Identification of Novel Therapeutic Molecular Targets in Inflammatory Bowel Disease by Using Genetic Databases. Clin Exp Gastroenterol. 2020 Oct.13:467-473. Pubmedid: 33116744. Pmcid: PMC7585167.
    • Mok SRS, Diehl DL, Confer BD, Johal AS, Khara HS. The 22-gauge core needle is not optimal for endoscopic ultrasound-guided liver biopsy. Endoscopy. 2020 Feb.52(2):157. Pubmedid: 31991474.
    • Mok SRS, Diehl DL. The Role of EUS in Liver Biopsy. Curr Gastroenterol Rep. 2019 Jan.21(2):6. Pubmedid: 30706151.
    • Mok SRS, Diehl DL, Johal AS, Khara HS, Confer BD, Mudireddy PR, Kovach AH, Diehl MM, Kirchner HL, Chen ZE. Endoscopic ultrasound-guided biopsy in chronic liver disease: a randomized comparison of 19-G FNA and 22-G FNB needles. Endosc Int Open. 2019 Jan.7(1):E62-E71. Pubmedid: 30648141. Pmcid: PMC6327728.
    • Mudireddy PR, Sethi A, Siddiqui AA, Adler DG, Nieto J, Khara H, Trindade A, Ho S, Benias PC, Draganov PV, Yang D, Mok S, Confer B, Diehl DL. EUS-guided drainage of postsurgical fluid collections using lumen-apposing metal stents: a multicenter study. Gastrointest Endosc. 2018 May.87(5):1256-1262. Pubmedid: 28843581.
    • Diehl DL, Mok SRS, Khara HS, Johal AS, Kirchner HL, Lin F. Heparin priming of EUS-FNA needles does not adversely affect tissue cytology or immunohistochemical staining. Endosc Int Open. 2018 Mar.6(3):E356-E362. Pubmedid: 29527558. Pmcid: PMC5842078.
    • Mok SRS, Diehl DL, Johal AS, Khara HS, Confer BD, Mudireddy PR, Kirchner HL, Chen ZE. A prospective pilot comparison of wet and dry heparinized suction for EUS-guided liver biopsy (with videos). Gastrointest Endosc. 2018 Dec.88(6):919-925. Pubmedid: 30120956.
    • Mok SRS, Khara HS, Johal AS, Confer BD, Diehl DL. Endoscopic treatment of internal hemorrhoids by use of a bipolar system. VideoGIE. 2017 Oct.2(10):290-292. Pubmedid: 30182083. Pmcid: PMC6119210.
    • Mok SRS, Khara HS, Johal AS, Confer BD, Diehl DL. Cholangioscopic appearance after radiofrequency ablation of cholangiocarcinoma. VideoGIE. 2017 Oct.2(10):279-283. Pubmedid: 30175304. Pmcid: PMC6117450.
    • Mok SRS, Ho HC, Shah P, Patel M, Gaughan JP, Elfant AB. Response. Gastrointest Endosc. 2017 Nov.86(5):926-927. Pubmedid: 29061263.
    • Chandel A, Scarpato B, Camacho J, McFarland M, Mok S. Glycogenic Hepatopathy: Resolution with Minimal Glucose Control. Case Reports Hepatol. 2017 May.2017:7651387. Pubmedid: 28529811. Pmcid: PMC5424186.
    • Mok SRS, Ho HC, Shah P, Patel M, Gaughan JP, Elfant AB. Lactated Ringer's solution in combination with rectal indomethacin for prevention of post-ERCP pancreatitis and readmission: a prospective randomized, double-blinded, placebo-controlled trial. Gastrointest Endosc. 2017 May.85(5):1005-1013. Pubmedid: 27816497.
    • Mok SR, Arif M, Diehl DL, Khara HS, Ho HC, Elfant AB. Safety and efficacy of minimal biliary sphincterotomy with papillary balloon dilation (m-EBS+EPBD) in patients using clopidogrel or anticoagulation. Endosc Int Open. 2017 Mar.5(3):E157-E164. Pubmedid: 28337485. Pmcid: PMC5361880.
    • Mok SRS, Ho HC, Shah P, Patel M, Gaughan JP, Elfant AB. Response. Gastrointest Endosc. 2017 Jul.86(1):249-250. Pubmedid: 28610863.
    • Mok SR, Ho HC, Gaughan JP, Elfant AB. Therapeutic Endoscopy Can Be Performed Safely in an Ambulatory Surgical Center: A Multicenter, Prospective Study. Diagn Ther Endosc. 2016 Nov.2016:7168280. Pubmedid: 27840569. Pmcid: PMC5093287.
    • Mok SR, Mohan S, Grewal N, Elfant AB, Judge TA. A genetic database can be utilized to identify potential biomarkers for biphenotypic hepatocellular carcinoma-cholangiocarcinoma. J Gastrointest Oncol. 2016 Aug.7(4):570-579. Pubmedid: 27563447. Pmcid: PMC4963376.
    • Mok SR, Mohan S, Elfant AB, Judge TA. The Acute Physiology and Chronic Health Evaluation IV, a New Scoring System for Predicting Mortality and Complications of Severe Acute Pancreatitis. Pancreas. 2015 Nov.44(8):1314-1319. Pubmedid: 26418901.
    • Mok SR, Judge TA, Peikin SR. Chicken Bone Impaction Diagnosed by Computer Tomography Angiography: A Rare Cause of Lower Gastrointestinal Bleeding. ACG Case Rep J. 2014 Oct.2(1):4-5. Pubmedid: 26157886. Pmcid: PMC4435347.
    • Mok SR, Avila J, Milcarek B, Kasama R. The NT-ProBNP Test in Subjects with End-Stage Renal Disease on Hemodialysis Presenting with Acute Dyspnea: Is Knowing Worth the Cost?. Emerg Med Int. 2013 Mar.2013:836497. Pubmedid: 23533765. Pmcid: PMC3606718.
    • Nader K, Mok S, Kalra A, Harb A, Schwarting R, Ferber A. Vanishing bile duct syndrome as a manifestation of Hodgkin's lymphoma: a case report and review of the literature. Tumori. 2013 Jul.99(4):e164-e168. Pubmedid: 24326854.
    • Mok SR, Punjabi V, Shklar DL. Neurosyphillis presenting with normal pressure hydrocephalus in a 76 year old man. Am J Case Rep. 2013 Apr.13:173-176. Pubmedid: 23569521. Pmcid: PMC3615923.
    • Mok SR, Mannino CL, Malin J, Drew ME, Henry P, Shivaprasad P, Milcarek B, Elfant AB, Judge TA. Does the urgency of endoscopic retrograde cholangiopancreatography (ercp)/percutaneous biliary drainage (pbd) impact mortality and disease related complications in ascending cholangitis? (deim-i study). J Interv Gastroenterol. 2012 Oct.2(4):161-167. Pubmedid: 23687602. Pmcid: PMC3655387.
  • Patient Comments

    Overall Satisfaction


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