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At Moffitt Cancer Center, the Total Cancer Care® (TCC) research protocol is a way that we can partner with patients and non-Moffitt patients with the goals of using data and biospecimens collected over time to (1) identify the needs of the patient and their families; (2) develop an evidence-based approach to meet those needs; and (3) develop markers to predict need so they can be prevented.

Patient participation and interest is the single most critical component of the Total Cancer Care® study. It was developed to specifically address the need for tissue collection and data collection over a patient’s lifetime. The valuable information can come from patients' donated blood and tissue samples, medical information, or questionnaires. By collecting valuable information during regularly scheduled visits, participants help us grow the study.

All patients 18 years old and older are eligible to participate. Research coordinators may visit with patients during their clinic visits to explain the study and then patients decide if they want to participate or they may ask for more information from their doctors or the study team. Participation is completely voluntary.

Watch this video to learn more about the TCC protocol:

Scientists are actively using the valuable information to answer many important questions about cancer, such as why treatment may not always have the same outcome in different patients. We hope this research can create new ways to personalize treatment and find better ways to prevent and diagnose cancer. More than 175,000 patients have enrolled in the Moffitt TCC study since it was launched in 2006. Each participant takes us one step closer to the next cancer breakthrough.

There are several ways our patients can learn more about Total Cancer Care® study:

  • Review the material on
  • Email
  • Learn more about TCC and sign up as part of the Moffitt appointment online registration process
  • Ask your clinical team about TCC when you come to the clinic