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376 Clinical Trials Found

Clinical Trial 23380

A Seamless Phase 1/2 Study to Evaluate the Safety and Efficacy of A2B694, an Autologous Logic-gated Tmod CAR T, in Heterozygous HLA-A*02 Adult with Recurrent Unresectable, Locally Advanced, or Metastatic Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
Disease Site: Cervix, Colorectal, Lung, Other Female Genital, Ovary, Uterus
PI: Avila, Monica

Clinical Trial 23580

A Phase 1/2 Open-Label, Multicenter, First-in-Human Study of the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of BH-30643 in Adult Subjects with Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations (SOLARA)
Disease Site: Lung
PI: Puri, Sonam

Clinical Trial 23549

Disease Site: Anus, Any Site, Breast, Cervix, Colon, Esophagus, Kaposi's sarcoma, Lip, Oral Cavity and Pharynx, Lung, Other Digestive Organ, Other Endocrine System, Other Urinary, Ovary, Rectum, Urinary Bladder
PI: Saltos, Andreas

Clinical Trial 23601

Venetoclax In Combination with ASTX727, an All-ORal TherapY for Chronic Myelomonocytic Leukemia and Other MDS/MPN with Excess Blasts (VICTORY MDS/MPN): a Randomized, Phase 2 Trial
Disease Site: Myeloid and Monocytic Leukemia
PI: Shallis, Rory

Clinical Trial 23679

The Phase III "High Five Trial" Five Fraction Radiation for High-Risk Prostate Cancer
Disease Site: Prostate
PI: Rishi, Anupam

Clinical Trial 23691

A Multicenter, Randomized, Double-blind, Phase 2/3 Study of Ficerafusp Alfa (BCA101) or Placebo in Combination with Pembrolizumab for First-Line Treatment of PD-L1-positive, Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
Disease Site: Larynx, Lip, Oral Cavity and Pharynx
PI: Chung, Christine

Clinical Trial 23710

A multicenter, open-label, randomized, phase 2 study of venetoclax and azacitidine plus cusatuzumab versus venetoclax and azacitidine alone in newly diagnosed AML patients who are not candidates for intensive therapy
Disease Site: Myeloid and Monocytic Leukemia
PI: Sallman, David

Clinical Trial 23719

A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of Inavolisib Plus a CDK4/6 Inhibitor and Letrozole Versus Placebo Plus a CDK4/6 Inhibitor and Letrozole in Patients with Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
Disease Site: Breast
PI: Extermann, Martine

Clinical Trial 17425

Randomized Phase II/III Trial of Adjuvant Radiation Therapy with Cisplatin, Docetaxel-Cetuximab, or Cisplatin-Atezolizumab in Pathologic High-Risk Squamous Cell Cancer of the Head and Neck
Disease Site: Larynx, Lip, Oral Cavity and Pharynx, Head & Neck, Mouth, lip
PI: Caudell, Jimmy

Clinical Trial 21143

A Single-Arm, Open-Label, Pilot Study of Concurrent Phototherapy and POTELIGEO (mogamulizumab-kpkc) in Early Stage Mycosis Fungoides (PLIGHT)
Disease Site: Mycosis Fungoides
PI: Sokol, Lubomir

Clinical Trial 20030

TAILOR RT: A Randomized Trial of Regional Radiotherapy in Biomarker Low Risk Node Positive and T3N0 Positive Breast Cancer
Disease Site: Breast
PI: Washington, Iman

Clinical Trial 21421

A Phase 3 (Pivotal Stage) Study of NBTXR3 Activated by Investigators Choice of Radiotherapy Alone or Radiotherapy in Combination with Cetuximab for Platinum-based Chemotherapy-ineligible Elderly Patients with Locally Advanced Head & Neck Squamous Cell Carcinoma
Disease Site: Lip, Oral Cavity and Pharynx
PI: Caudell, Jimmy