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376 Clinical Trials Found

Clinical Trial 23620

A Modular Phase I/II, Open-label, Multicentre Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of AZD2962, an IRAK4 inhibitor, as Monotherapy and in Combination with other Agents, in Participants with Haematologic Neoplasms
Disease Site: Soft Tissue
PI: Sallman, David

Clinical Trial 23740

Disease Site: Lymphoid Leukemia
PI: Silva Rondon, Carlos

Clinical Trial 19868

First in Human Phase I Study of 225Actinium-DOTA-Ahx-MC1RL (225Ac-MTI-201) in Metastatic Melanoma
Disease Site: Eye and Orbit, Melanoma, skin
PI: Khushalani, Nikhil

Clinical Trial 20497

A Multicenter, Open-Label Phase 1/2 Trial Evaluating the Safety, Tolerability and Efficacy of MORAb-202, a Folate Receptor Alpha (FRA)-Targeting Antibody-Drug Conjugate (ADC) in Subjects with Selected Tumor Types
Disease Site: Ovary
PI: Wenham, Robert

Clinical Trial 20733

A Phase III Trial to Evaluate the Efficacy of the Addition of Inotuzomab Ozogamicin (a conjugated anti-CD22 monoclonal antibody) to Frontline Therapy in Young Adults (ages 18-39 years) with Newly Diagnosed Precusor B-cell ALL
Disease Site: Myeloid and Monocytic Leukemia
PI: Vargas Madueno, Fernando

Clinical Trial 21074

A Phase 2 Randomized Study of Osimertinib Versus Osimertinib Plus Chemotherapy for Patients with Metastatic EGFR-Mutant Lung Cancers That Have Detectable EGFRMutant cfDNA in Plasma After Initiation of Osimertinib
Disease Site: Lung
PI: Pellini, Bruna

Clinical Trial 23249

PRE-I-SPY TRIAL - PRE-Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging And moLecular Analysis: A Phase I/Ib platform trial
Disease Site: Breast
PI: Han, Heather

Clinical Trial 21415

Disease Site: Other Hematopoietic
PI: Kuykendall, Andrew

Clinical Trial 21923

A Phase 1b/2 Multicenter, Open-label Study to Evaluate the Safety and Efficacy of TTI-101 as Monotherapy and in Combination in Participants with Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma
Disease Site: Liver
PI: Kim, Richard

Clinical Trial 21951

A Randomized, Open-Label, Phase 3 Study to Evaluate Zimberelimab and Domvanalimab in Combination with Chemotherapy Versus Pembrolizumab with Chemotherapy for the First-Line Treatment of Patients With Metastatic Non Small Cell Lung Cancer With No Epidermal Growth Factor Receptor or Anaplastic Lymphoma Kinase Genomic Tumor Aberrations (STAR-121)
Disease Site: Lung
PI: Gray, Jhanelle

Clinical Trial 22263

A Phase 1b Study of Oral AS-1763 in Patients with Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or B-cell Non-Hodgkin Lymphoma
Disease Site: Lymphoid Leukemia, Non-Hodgkin's Lymphoma, Soft Tissue
PI: Pinilla-Ibarz, Javier

Clinical Trial 22294

A Randomized Phase III Study of Neoadjuvant Chemotherapy followed by Surgery versus Surgery Alone for Patients with High Risk RetroPeritoneal Sarcoma (STRASS 2)
Disease Site: Soft Tissue
PI: Mullinax, John