Claudia Paba Prada, MD

Dr. Paba Prada earned her MD degree from Universidad Industrial de Santander in Bucaramanga, Colombia. She completed an Internal Medicine Residency at Pennsylvania Hospital, Philadelphia, and a Hematology/Oncology Fellowship at the University of Tennessee Health Science Center, Memphis. She then completed an Advanced Fellowship in Hematologic Malignancies at Dana Farber Cancer Institute, Boston. Following her fellowships, Dr. Paba Prada was an Attending Physician in the Department of Medical Oncology at Brigham and Women’s Hospital and a Clinical Physician in the Department of Hematologic Malignancies at Dana-Farber Cancer Institute. Prior to joining Moffitt, Dr. Paba Prada was a Clinical Physician in the Department of Hematologic Malignancies at Miami Cancer Institute.

Dr. Paba Prada has a clinical interest in the management of plasma cell disorders, including monoclonal gammopathy of unknown significance, multiple myeloma, AL amyloidosis, POEMS syndrome and Waldenstrom macroglobulinemia. Her research focus is multiple myeloma.

 

 

 

Education & Training

Fellowship:

• Dana Farber Cancer Institute - Hematologic Malignancies
• University of Tennessee Health Sciences Center - Hematology & Oncology

Residency:

• Pennsylvania Hospital - Internal Medicine

Medical School:

• Universidad Industrial de Santander - MD

• Rowinsky EK, Paner A, Berdeja JG, Paba-Prada C, Venugopal P, Porkka K, Gullbo J, Linder S, Loskog A, Richardson PG, Landgren O. Phase 1 study of the protein deubiquitinase inhibitor VLX1570 in patients with relapsed and/or refractory multiple myeloma. Invest New Drugs. 2020 Oct.38(5):1448-1453. Pubmedid: 32125598. Pmcid: PMC7497669.
• Richardson PG, Bringhen S, Voorhees P, Plesner T, Mellqvist UH, Reeves B, Paba-Prada C, Zubair H, Byrne C, Chauhan D, Anderson K, Nordström E, Harmenberg J, Palumbo A, Sonneveld P. Melflufen plus dexamethasone in relapsed and refractory multiple myeloma (O-12-M1): a multicentre, international, open-label, phase 1-2 study. Lancet Haematol. 2020 May.7(5):e395-e407. Pubmedid: 32213344.
• Ghobrial IM, Liu CJ, Zavidij O, Azab AK, Baz R, Laubach JP, Mishima Y, Armand P, Munshi NC, Basile F, Constantine M, Vredenburgh J, Boruchov A, Crilley P, Henrick PM, Hornburg KTV, Leblebjian H, Chuma S, Reyes K, Noonan K, Warren D, Schlossman R, Paba-Prada C, Anderson KC, Weller E, Trippa L, Shain K, Richardson PG. Phase I/II trial of the CXCR4 inhibitor plerixafor in combination with bortezomib as a chemosensitization strategy in relapsed/refractory multiple myeloma. Am J Hematol. 2019 Nov.94(11):1244-1253. Pubmedid: 31456261.
• Hari P, Paba-Prada CE, Voorhees PM, Frye J, Chang YL, Moreau P, Zonder J, Boccia R, Shain KH. Efficacy and safety results from a phase 1b/2, multicenter, open-label study of oprozomib and dexamethasone in patients with relapsed and/or refractory multiple myeloma. Leuk Res. 2019 Aug.83:106172. Pubmedid: 31229804. Pmcid: PMC6871647.
• O'Donnell EK, Laubach JP, Yee AJ, Chen T, Huff CA, Basile FG, Wade PM, Paba-Prada CE, Ghobrial IM, Schlossman RL, Burke JN, Harrington CC, Lively KJ, Lyons HF, Munshi NC, Anderson KC, Trippa L, Richardson PG, Raje NS. A phase 2 study of modified lenalidomide, bortezomib and dexamethasone in transplant-ineligible multiple myeloma. Brit J Haematol. 2018 Jul.182(2):222-230. Pubmedid: 29740809. Pmcid: PMC6074026.
• Lee N, Lockwood SJ, Richardson P, Paba-Prada C, Saavedra AP. IgA multiple myeloma in a patient with an IgG pemphigus foliaceus-like exanthem. Int J Dermatol. 2017 Oct.56(10):1058-1060. Pubmedid: 28856664.
• Laubach JP, Paba Prada CE, Richardson PG, Longo DL. Daratumumab, Elotuzumab, and the Development of Therapeutic Monoclonal Antibodies in Multiple Myeloma. Clin Pharmacol Ther. 2017 Jan.101(1):81-88. Pubmedid: 27806428.
• Richardson PG, Kumar S, Laubach JP, Paba-Prada C, Gupta N, Berg D, van de Velde H, Moreau P. New developments in the management of relapsed/refractory multiple myeloma - the role of ixazomib. J Blood Med. 2017 Aug.8:107-121. Pubmedid: 28860887. Pmcid: PMC5573039.
• Castillo JJ, Jurczyszyn A, Brozova L, Crusoe E, Czepiel J, Davila J, Dispenzieri A, Eveillard M, Fiala MA, Ghobrial IM, Gozzetti A, Gustine JN, Hajek R, Hungria V, Jarkovsky J, Jayabalan D, Laubach JP, Lewicka B, Maisnar V, Manasanch EE, Moreau P, Morgan EA, Nahi H, Niesvizky R, Paba-Prada C, Pika T, Pour L, Reagan JL, Richardson PG, Shah J, Spicka I, Vij R, Waszczuk-Gajda A, Gertz MA. IgM myeloma: A multicenter retrospective study of 134 patients. Am J Hematol. 2017 Aug.92(8):746-751. Pubmedid: 28383205.
• Neri P, Bahlis NJ, Paba-Prada C, Richardson P. Treatment of Relapsed/Refractory Multiple Myeloma. Cancer Treat Res. 2016 Oct.169:169-194. Pubmedid: 27696263.
• Jurczyszyn A, Olszewska-Szopa M, Vesole AS, Vesole DH, Siegel DS, Richardson PG, Paba-Prada C, Callander NS, Huras H, Skotnicki AB. Multiple Myeloma in Pregnancy--A Review of the Literature and a Case Series. Clin Lymphoma Myeloma Leuk. 2016 Mar.16(3):e39-e45. Pubmedid: 26847816.
• Weinstock M, Aljawai Y, Morgan EA, Laubach J, Gannon M, Roccaro AM, Varga C, Mitsiades CS, Paba-Prada C, Schlossman R, Munshi N, Anderson KC, Richardson PP, Weller E, Ghobrial IM. Incidence and clinical features of extramedullary multiple myeloma in patients who underwent stem cell transplantation. Brit J Haematol. 2015 Jun.169(6):851-858. Pubmedid: 25833301. Pmcid: PMC5944324.
• Leblebjian H, Noonan K, Paba-Prada C, Treon SP, Castillo JJ, Ghobrial IM. Cyclophosphamide, bortezomib, and dexamethasone combination in waldenstrom macroglobulinemia. Am J Hematol. 2015 Jun.90(6):E122-E123. Pubmedid: 25703132.
• Varga C, Xie W, Laubach J, Ghobrial IM, O'Donnell EK, Weinstock M, Paba-Prada C, Warren D, Maglio ME, Schlossman R, Munshi NC, Raje N, Weller E, Anderson KC, Mitsiades CS, Richardson PG. Development of extramedullary myeloma in the era of novel agents: no evidence of increased risk with lenalidomide-bortezomib combinations. Brit J Haematol. 2015 Jun.169(6):843-850. Pubmedid: 26032514.
• Banwait R, Aljawai Y, Cappuccio J, McDiarmid S, Morgan EA, Leblebjian H, Roccaro AM, Laubach J, Castillo JJ, Paba-Prada C, Treon S, Redd R, Weller E, Ghobrial IM. Extramedullary Waldenström macroglobulinemia. Am J Hematol. 2015 Feb.90(2):100-104. Pubmedid: 25349134.
• Rosenbaum C, Jasielec J, Laubach J, Paba Prada C, Richardson P, Jakubowiak AJ. Evolving strategies in the initial treatment of multiple myeloma. Semin Oncol. 2013 Oct.40(5):592-601. Pubmedid: 24135404.
• Chauhan D, Ray A, Viktorsson K, Spira J, Paba-Prada C, Munshi N, Richardson P, Lewensohn R, Anderson KC. In vitro and in vivo antitumor activity of a novel alkylating agent, melphalan-flufenamide, against multiple myeloma cells. Clin Cancer Res. 2013 Jun.19(11):3019-3031. Pubmedid: 23584492. Pmcid: PMC4098702.
• Richardson PG, Laubach J, Paba-Prada C, Anderson KC. IgD and IgE variants of myeloma: valuable insights and therapeutic opportunities. Oncology (Williston Park). 2013 Aug.27(8):803-4, 806. Pubmedid: 24133830.