Sam Freyaldenhoven, MD, MS
Sam Freyaldenhoven, MD, MS
Specialty: Thoracic Surgery
Program: Thoracic Oncology
Language(s): English
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Overview
Cancer Focus:
Lung Cancer, Mesothelioma, Pancoast TumorDr. Freyaldenhoven received his MD degree from the University of Arkansas for Medical Sciences College of Medicine, where he also earned his MS in biochemistry and molecular biology. He completed a Research Fellowship at Brigham and Women’s Hospital, Division of Thoracic and Cardiac Surgery; then he completed a General Surgery Residency at the University of South Florida. Dr. Freyaldenhoven most recently completed a Clinical Fellowship at Brigham and Women’s Hospital, Division of Thoracic and Cardiac Surgery.
Dr. Freyaldenhoven’s clinical interests focus on providing individualized care for patients with thoracic cancers, leveraging advanced surgical techniques and therapies, and collaborating with multidisciplinary teams to ensure optimal outcomes and patient satisfaction. His research focus is on patient-centered clinical investigation, with a specific emphasis on enhancing treatments and outcomes.
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Publications
- Robinson LA, Bryant S, Sun X, Kaki MS, Freyaldenhoven ST, Schwer T, Bailey A, Kim Y. Implantation of polyglycolic acid mesh over lung resection staple lines to prevent air leaks. JTCVS Tech. 2025 Aug.32:163-171. Pubmedid: 40814658. Pmcid: PMC12348291.
- Freyaldenhoven ST, Tsukada H. Robotics in the diagnosis and staging of lung cancer. J Surg Oncol. 2023 Feb.127(2):258-261. Pubmedid: 36630090.
- Lapidot M, Mazzola E, Freyaldenhoven S, De León LE, Jaklitsch MT, Bueno R. Postoperative Empyema After Pleurectomy Decortication for Malignant Pleural Mesothelioma. Ann Thorac Surg. 2022 Oct.114(4):1214-1219. Pubmedid: 34619137.
- Lapidot M, Gill RR, Mazzola E, Freyaldenhoven S, Swanson SJ, Jaklitsch MT, Sugarbaker DJ, Bueno R. Pleurectomy Decortication in the Treatment of Malignant Pleural Mesothelioma: Encouraging Results and Novel Prognostic Implications Based on Experience in 355 Consecutive Patients. Ann Surg. 2022 Jun.275(6):1212-1220. Pubmedid: 33278174.
- Rodriguez M, Dezube AR, Bravo-Iniguez CE, Fox S, De León LE, Tarascio J, Freyaldenhoven S, Mentzer SJ, Swanson SJ, Bueno R, Rochefort MM, Marshall MB, Jaklitsch MT. Impact of Neoadjuvant Chemoradiation on Adverse Events After Bronchial Sleeve Resection. Ann Thorac Surg. 2021 Sep.112(3):890-896. Pubmedid: 33171174.
- De Rienzo A, Chirieac LR, Hung YP, Severson DT, Freyaldenhoven S, Gustafson CE, Dao NT, Meyerovitz CV, Oster ME, Jensen RV, Yeap BY, Bueno R, Richards WG. Large-scale analysis of BAP1 expression reveals novel associations with clinical and molecular features of malignant pleural mesothelioma. J Pathol. 2021 Jan.253(1):68-79. Pubmedid: 32944962. Pmcid: PMC7756745.
- De León LE, Bravo-Iñiguez CE, Fox S, Tarascio J, Freyaldenhoven S, Lapidot M, Jaklitsch MT, Bueno R. Routine surveillance for diagnosis of venous thromboembolism after pleurectomy for malignant pleural mesothelioma. J Thorac Cardiovasc Surg. 2020 Oct.160(4):1064-1073. Pubmedid: 32113716. Pmcid: PMC7390678.
- Lapidot M, Freyaldenhoven S, Bueno R. New concepts in the treatment of malignant pleural mesothelioma. J Thorac Dis. 2018 Mar.10(3):1283-1285. Pubmedid: 29708159. Pmcid: PMC5906329.
- Ziu E, Mercado CP, Li Y, Singh P, Ahmed BA, Freyaldenhoven S, Lensing S, Ware J, Kilic F. Down-regulation of the serotonin transporter in hyperreactive platelets counteracts the pro-thrombotic effect of serotonin. J Mol Cell Cardiol. 2012 May.52(5):1112-1121. Pubmedid: 22366712. Pmcid: PMC3327821.
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Patient Comments
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Awards and Expertise
Voted top doctor in Thoracic Disease in Tampa Magazine's Top Doctors 2025.
330 patients rated this provider
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