Sephalie Patel, MD

Dr. Patel is currently Chair of the Department of Anesthesiology and Critical Care. Dr. Patel graduated from Cornell University with a degree in Mechanical and Aerospace Engineering. She went on to the Massachusetts Institute of Technology to obtain a Master of Science in Mechanical Engineering. It was during graduate school she decided to pivot to medicine and completed a Bioengineering Research Fellowship at the National Institutes of Health in 2004. She went on to Emory University School of Medicine where she received her MD degree in 2008. Dr. Patel completed her residency in the Department of Anesthesiology at the University of Florida in Gainesville, FL where she won the prestigious Chairman’s Award during her final year, 2012. She went on to complete a fellowship in Regional Anesthesia at the Hospital for Special Surgery in New York, NY after which she joined Moffitt Cancer Center in 9/2013.  Since joining Moffitt, Dr. Patel has started the Enhanced Recovery after Surgery program which focuses on evidence based, cost-effective perioperative care of the surgical patient. She also started the 3rd year medical student rotation which continues to be one of few opportunities for USF medical students to have exposure to Anesthesiology. Dr. Patel started the patient blood management program at Moffitt which includes the development of a maximum surgical blood ordering schedule, preoperative anemia optimization program, and bloodless medicine program. Her research interests include opioid sparing anesthetic techniques, blood management, preoperative nutrition optimization of the surgical patient and has published over 50 peer reviewed manuscripts. Dr. Patel was Director of ERAS and Research from 2015-2022, Vice Chair of Department of Anesthesiology from 2022-2023, and appointed Chair of Department of Anesthesiology in 2023. She currently is a Fellow of the American Society of Anesthesiologists, member of the Association of University Anesthesiologists, and an Oral Board Examiner for the American Board of Anesthesiology.

Education & Training

Fellowship:

• Hospital for Special Surgery - Anesthesia
• NIH - Intramural Research

Residency:

• University of Florida -

Medical School:

• Emory University School of Medicine - MD

• Pettit MS, Crowder SL, Ackerman RS, Hafez O, Poch MA, Patel SY. Preoperative Nutritional Status and Enhanced Recovery after Surgery (ERAS) Prior to Radical Cystectomy: A Review of the Literature. Nutr Cancer. 2023 Aug.75(9):1743-1751. Pubmedid: 37553951.
• Dahmen AS, Phuoc VH, Cohen JB, Sexton WJ, Patel SY. Bloodless surgery in urologic oncology: A review of hematologic, anesthetic, and surgical considerations. Urol Oncol. 2023 Apr.41(4):192-203. Pubmedid: 36470804.
• Cohen JB, Patel SY. Parallels between our response to COVID-19 and approach to patient safety. Brit J Anaesth. 2022 Nov.129(5):647-649. Pubmedid: 36030133. Pmcid: PMC9340057.
• Patel SY, Trona N, Alford B, Laborde JM, Kim Y, Li R, Manley BJ, Gilbert SM, Sexton WJ, Spiess PE, Poch MA. Preoperative immunonutrition and carbohydrate loading associated with improved bowel function after radical cystectomy. Nutr Clin Pract. 2022 Feb.37(1):176-182. Pubmedid: 33900647.
• Robinson LA, Tanvetyanon T, Grubbs D, Robinson NA, Pierce CM, McCarthy K, Garcia-Getting R, Patel S. Preoperative nutrition-enhanced recovery after surgery protocol for thoracic neoplasms. J Thorac Cardiovasc Surg. 2021 Sep.162(3):710-720.e1. Pubmedid: 32713631.
• Cohen JB, Patel SY. The Successful Anesthesia Patient Safety Officer. Anesth Analg. 2021 Sep.133(3):816-820. Pubmedid: 34280174.
• Patel SY, Kubal TE, Li R, Manley BJ, Gilbert SM, Sexton WJ, Spiess PE, Boulware D, Poch MA. Prevalence of Preoperative Iron Deficiency Anemia: A Case Series Among Patients Undergoing Radical Cystectomy. A A Pract. 2021 May.15(5):e01477. Pubmedid: 33999012.
• Patel S, Suz P, Powers BD, Anaya DA. Epidural analgesia for hepatopancreatobiliary operations and postoperative urinary tract infections: an unrecognized association of "best-practices" and adverse outcomes. HPB (Oxford). 2021 Jan.23(1):71-79. Pubmedid: 32414659.
• Patel SY, Ackerman RS, Boulware D, Poch MA. Epidural anesthesia may be associated with increased postoperative complications in the elderly population undergoing radical cystectomy: an analysis from the National Surgical Quality Improvement Project (NSQIP) database. World J Urol. 2021 Feb.39(2):433-441. Pubmedid: 32318858. Pmcid: PMC7771372.
• Ackerman RS, Aldawoodi NN, Muncey AR, Patel SY, Coughlin EC, Mhaskar RS. Intravenous versus Volatile Anesthesia and Cancer Outcomes: The Value of Precise Definitions and Pitfalls of Multivariate Analysis. Anesth Analg. 2021 Aug.133(2):e26-e27. Pubmedid: 34257210.
• Warner MA, Shore-Lesserson L, Shander A, Patel SY, Perelman SI, Guinn NR. Perioperative Anemia: Prevention, Diagnosis, and Management Throughout the Spectrum of Perioperative Care. Anesth Analg. 2020 May.130(5):1364-1380. Pubmedid: 32167979.
• Petitt MS, Ackerman RS, Hanna MM, Chen L, Mhaskar RS, Fernandez DC, Patel SY. Anesthetic and analgesic methods for gynecologic brachytherapy: A meta-analysis and systematic review. Brachytherapy. 2020 May.19(3):328-336. Pubmedid: 32122807.
• Muncey AR, Patel SY, Whelan CJ, Ackerman RS, Gatenby RA. The Intersection of Regional Anesthesia and Cancer Progression: A Theoretical Framework. Cancer Control. 2020 Jan.27(1). Pubmedid: 33070618. Pmcid: PMC7791454.
• Ackerman RS, Hirschi M, Trona N, Joyce DM, Evans T, Patel SY. Incidence of Thromboembolic Events in Oncology Patients Receiving Intraoperative Tranexamic Acid During Orthopedic Surgery: A Retrospective Review at a Comprehensive Cancer Center. A A Pract. 2020 Jan.14(2):63-66. Pubmedid: 31703004.
• Cohen JB, Patel SY. Getting to Zero Patient Harm: From Improving Our Existing Tools to Embracing a New Paradigm. Anesth Analg. 2020 Feb.130(2):547-549. Pubmedid: 31764161.
• Sun J, Kirichenko DA, Chung JL, Carr MJ, Eroglu Z, Khushalani NI, Markowitz J, Messina JL, Sondak VK, Zager JS, Patel SY. Perioperative Outcomes of Melanoma Patients Undergoing Surgery After Receiving Immunotherapy or Targeted Therapy. World J Surg. 2020 Apr.44(4):1283-1293. Pubmedid: 31811340.
• Ackerman RS, Tufts CW, DePinto DG, Chen J, Altshuler JR, Serdiuk A, Cohen JB, Patel SY. How Sweet Is This? A Review and Evaluation of Preoperative Carbohydrate Loading in the Enhanced Recovery After Surgery Model. Nutr Clin Pract. 2020 Apr.35(2):246-253. Pubmedid: 31637778.
• Cohen JB, Hirschi MR, Patel SY, Liu J. Non-thoracic Source of Bleeding During Left-sided Thoracic Surgery. Cureus. 2019 May.11(5):e4593. Pubmedid: 31309018. Pmcid: PMC6609276.
• Ackerman RS, Hirschi M, Alford B, Evans T, Kiluk JV, Patel SY. Enhanced REVENUE After Surgery? A Cost-Standardized Enhanced Recovery Pathway for Mastectomy Decreases Length of Stay. World J Surg. 2019 Mar.43(3):839-845. Pubmedid: 30456482.
• Gonsalves SG, Dirksen RT, Sangkuhl K, Pulk R, Alvarellos M, Vo T, Hikino K, Roden D, Klein T, Mark Poler S, Patel S, Caudle KE, Gordon R, Brandom B, Biesecker LG. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for the Use of Potent Volatile Anesthetic Agents and Succinylcholine in the Context of RYR1 or CACNA1S Genotypes. Clin Pharmacol Ther. 2019 Jun.105(6):1338-1344. Pubmedid: 30499100. Pmcid: PMC6513720.
• Aldawoodi NN, Escher AR, Ninan D, Patel SY. Transesophageal Echocardiography During Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy: A Novel Approach. Cureus. 2019 Jul.11(7):e5062. Pubmedid: 31328075. Pmcid: PMC6624119.
• Ackerman RS, Cohen JB, Getting REG, Patel SY. Are you seeing this: the impact of steep Trendelenburg position during robot-assisted laparoscopic radical prostatectomy on intraocular pressure: a brief review of the literature. J Robot Surg. 2019 Feb.13(1):35-40. Pubmedid: 30047103.
• Patel SY, Garcia Getting RE, Alford B, Hussein K, Schaible BJ, Boulware D, Lee JK, Gilbert SM, Powsang JM, Sexton WJ, Spiess PE, Poch MA. Improved Outcomes of Enhanced Recovery After Surgery (ERAS) Protocol for Radical Cystectomy with Addition of a Multidisciplinary Care Process in a US Comprehensive Cancer Care Center. World J Surg. 2018 Sep.42(9):2701-2707. Pubmedid: 29750321. Pmcid: PMC7771278.
• Chipollini J, Alford B, Boulware DC, Forget P, Gilbert SM, Lockhart JL, Pow-Sang JM, Sexton WJ, Spiess PE, Poch MA, Patel SY. Epidural anesthesia and cancer outcomes in bladder cancer patients: is it the technique or the medication? A matched-cohort analysis from a tertiary referral center. BMC Anesthesiol. 2018 Nov.18(1):157. Pubmedid: 30390636. Pmcid: PMC6215353.
• Hafez O, Ackerman RS, Evans T, Patel SY, Padalia DM. Mental Nerve Blocks for Lip Brachytherapy: A Case Report. A A Pract. 2018 May.10(10):265-266. Pubmedid: 29757796.
• Evans T, Hanna M, Hafez O, Patel SY. Use of Laryngeal Mask Airway to Preoxygenate and Ventilate Through a Laryngeal Stoma in a Patient Undergoing General Anesthesia: A Case Report. A A Pract. 2018 Jun.10(11):296-297. Pubmedid: 29634570.
• Evans T, Patel S. Two Consecutive Preoperative Cardiac Arrests Involving Vancomycin in a Patient Presenting for Hip Disarticulation: A Case Report. A A Case Rep. 2017 Nov.9(9):262-264. Pubmedid: 28622151.
• Chipollini JJ, Tang DH, Patel SY, Garcia-Getting RE, Gilbert SM, Pow-Sang JM, Sexton WJ, Spiess PE, Poch MA. Perioperative Transfusion of Leukocyte-depleted Blood Products in Contemporary Radical Cystectomy Cohort Does Not Adversely Impact Short-term Survival. Urology. 2017 May.103:142-148. Pubmedid: 28011275.
• Groshev A, Padalia D, Patel S, Garcia-Getting R, Sahebjam S, Forsyth PA, Vrionis FD, Etame AB. Clinical outcomes from maximum-safe resection of primary and metastatic brain tumors using awake craniotomy. Clin Neurol Neurosurg. 2017 Jun.157:25-30. Pubmedid: 28384595.
• Chipollini J, Tang DH, Hussein K, Patel SY, Garcia-Getting RE, Pow-Sang JM, Gilbert SM, Sexton WJ, Spiess PE, Poch MA. Does Implementing an Enhanced Recovery After Surgery Protocol Increase Hospital Charges? Comparisons From a Radical Cystectomy Program at a Specialty Cancer Center. Urology. 2017 Jul.105:108-112. Pubmedid: 28342928.
• Patel S, Hafez O, Sexton WJ, Edwards DA. Perioperative Management of a Patient With an Intrathecal Drug Delivery Device Infusing Ziconotide: A Case Report. A A Case Rep. 2017 Feb.8(4):78-80. Pubmedid: 28195861.
• Patel SY, Edwards DA, Boulware DC, Serdiuk A, Cook SJ, Benson K, Rice MJ. A novel approach to improving efficiency and cost saving in preoperative blood preparation. Transfusion. 2017 Dec.57(12):3035-3039. Pubmedid: 28940392.
• Patel SY, Evans RM, Garcia Getting RE, Suz P. Pectoral Nerve and Transverse Abdominis Plane Block in a Patient Undergoing Mastectomy With Transverse Rectus Abdominis Muscle Flap: A Case Report. A A Case Rep. 2017 Apr.8(8):210-212. Pubmedid: 28118214.
• Alvarellos ML, McDonagh EM, Patel S, McLeod HL, Altman RB, Klein TE. PharmGKB summary: succinylcholine pathway, pharmacokinetics/pharmacodynamics. Pharmacogenet Genomics. 2015 Dec.25(12):622-630. Pubmedid: 26398623. Pmcid: PMC4631707.
• Williamson SD, Lam Y, Younis HF, Huang H, Patel S, Kaazempur-Mofrad MR, Kamm RD. On the Sensitivity of Wall Stresses in Diseased Arteries to Variable Material Properties. J Biomech Eng. 2003.125(1):147-155.
• Kaazempur-Mofrad MR, Younis HF, Patel S, Isasi AG, Chung C, Chan RC, Hinton DP, Lee RT, Kamm RD. Cyclic Strain in Human Carotid Bifurcation and its Potential Correlation to Atherogenesis: Idealized and Anatomically-Realistic Models. J Eng Math. 2003.47(3-4):299-314.
• Poch MA, Patel S, Garcia-Getting R. The present and future enhanced recovery after surgery for bladder cancer. Int Braz J Urol. 44(6):1266-1271. Pubmedid: 30044593. Pmcid: PMC6442167.

Voted top doctor in Anesthesiology in Tampa Magazine’s Top Doctors 2025.

Voted top doctor in Anesthesiology in Tampa Magazine's Top Doctors 2024.