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Clinical Trial Search

59 Clinical Trials Found

Clinical Trial 23697

A Phase 1/1b, Open-label, Multicenter, First-in-human Dose Escalation and Dose Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Anti-tumor Activity of VVD-159642, a RAS-PI3KA Inhibitor, as a Single Agent and in Combination in Participants With Advanced Solid Tumors
Disease Site: Any Site, Breast, Cervix, Corpus Uteri, Esophagus, Lip, Oral Cavity and Pharynx, Lung, Melanoma, skin, Other Digestive Organ, Other Female Genital, Other Skin, Ovary, Pancreas, Prostate, Small Intestine, Stomach
PI: Haura, Eric

Clinical Trial 23584

A Phase I Dose Finding and Phase II Randomized Trial of Iadademstat Combined with Immune Checkpoint Inhibition Maintenance After Initial Chemoimmunotherapy in Patients with Extensive-Stage Small Cell Lung Cancer
Disease Site: Lung, Small cell lung cancer
PI: Puri, Sonam

Clinical Trial 23565

LUNAR-2: Pivotal, Randomized, Open-Label Study of Tumor Treating Fields (TTFields, 150 kHz) Concomitant with Pembrolizumab and Platinum Based Chemotherapy for the Treatment of Metastatic Non-Small Cell Lung Cancer
Disease Site: Lung
PI: Rosenberg, Stephen

Clinical Trial 23582

A Phase II, multisite, open-label, single arm trial of BNT327 in combination with docetaxel in second-line stage IV non-small cell lung cancer (NSCLC) following chemoimmunotherapy
Disease Site: Lung
PI: Puri, Sonam

Clinical Trial 23585

Disease Site: Breast, Colon, Lung, Rectum
PI: Han, Heather

Clinical Trial 21626

A Phase 1, Open-Label, Multicenter Study to Assess Safety, Tolerability, PK, and Efficacy of MK-1084 as Monotherapy and in Combination with Pembrolizumab in Subjects with KRASG12C Mutant Advanced Solid Tumors
Disease Site: Lung
PI: Gray, Jhanelle

Clinical Trial 20386

Targeting ODC as an Immunotherapeutic Target in STK11 (LKB1) Pathway-Deficient NSCLC
Disease Site: Lung
PI: Gray, Jhanelle

Clinical Trial 22079

A Phase 1/2, Open-Label Study of PD-1 Knockout Tumor-Infiltrating Lymphocytes (IOC-4001) in Participants with Unresectable or Metastatic Melanoma or Stage III or IV Non-Small-Cell Lung Cancer
Disease Site: Lung, Melanoma, skin
PI: Karapetyan, Lilit

Clinical Trial 23180

Disease Site: Lung
PI: Gray, Jhanelle

Clinical Trial 23132

A Phase 1 Study of SGN-EGFRd2 in Advanced Solid Tumors
Disease Site: Colon, Lung, Rectum
PI: Kim, Richard

Clinical Trial 23319

A Randomized Phase III Trial of Chemo-Immunotherapy vs Immunotherapy Alone for the Vulnerable older adult with Advanced Non-Small Cell Lung Cancer: The ACHIEVE Study
Disease Site: Lung, Non small cell lung cancer
PI: Al-Jumayli, Mohammed

Clinical Trial 23535

Disease Site: Lung
PI: Puri, Sonam