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Clinical Trial Search

59 Clinical Trials Found

Clinical Trial 23380

A Seamless Phase 1/2 Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Autologous Logic-gated Tmod CAR T Protducts in Heterozygous HLA-A*02 Adult with Recurrent Unresectable, Locally Advanced, or Metastatic Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
Disease Site: Cervix, Colorectal, Lung, Other Female Genital, Ovary, Uterus
PI: Avila, Monica

Clinical Trial 23580

A Phase 1/2 Open-Label, Multicenter, First-in-Human Study of the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of BH-30643 in Adult Subjects with Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations (SOLARA)
Disease Site: Lung
PI: Puri, Sonam

Clinical Trial 23549

Disease Site: Anus, Any Site, Breast, Cervix, Colon, Esophagus, Kaposi's sarcoma, Lip, Oral Cavity and Pharynx, Lung, Other Digestive Organ, Other Endocrine System, Other Urinary, Ovary, Rectum, Urinary Bladder
PI: Saltos, Andreas

Clinical Trial 23094

A Randomized, Double-Blind Phase 2/3 Study of Fianlimab (Anti-LAG-3 antibody) in Combination with Cemiplimab (Anti-PD-1 antibody) versus Cemiplimab Monotherapy in First-Line Treatment of Patients with Advanced Non-Small Cell Lung Cancer (NSCLC) with Tumors Expressing PD-L1 >=50%
Disease Site: Lung, Non small cell lung cancer
PI: Saltos, Andreas

Clinical Trial 23183

Disease Site: Lung
PI: Creelan, Benjamin

Clinical Trial 23482

A Phase 3 Study of the Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor NVL-655 Compared to Alectinib in First-Line Treatment of Patients With ALK-Positive Advanced Non-Small Cell Lung Cancer (ALKAZAR)
Disease Site: Lung
PI: Creelan, Benjamin

Clinical Trial 23576

A Phase II/III, multisite, randomized master protocol for a global trial of BNT327 in combination with chemotherapy and other investigational agents in first-line non-small cell lung cancer
Disease Site: Lung
PI: Saltos, Andreas

Clinical Trial 21630

Disease Site: Lung
PI: Gray, Jhanelle

Clinical Trial 20530

NAUTIKA1: A MULTICENTER, PHASE II, NEOADJUVANT AND ADJUVANT STUDY OF MULTIPLE THERAPIES IN BIOMARKER-SELECTED PATIENTS WITH RESECTABLE STAGES IB-III NON-SMALL CELL LUNG CANCER
Disease Site: Lung
PI: Saltos, Andreas

Clinical Trial 21951

A Randomized, Open-Label, Phase 3 Study to Evaluate Zimberelimab and Domvanalimab in Combination with Chemotherapy Versus Pembrolizumab with Chemotherapy for the First-Line Treatment of Patients With Metastatic Non Small Cell Lung Cancer With No Epidermal Growth Factor Receptor or Anaplastic Lymphoma Kinase Genomic Tumor Aberrations (STAR-121)
Disease Site: Lung
PI: Gray, Jhanelle

Clinical Trial 23160

Disease Site: Lung
PI: Chiappori, Alberto

Clinical Trial 23480

Disease Site: Any Site, Breast, Esophagus, Kidney, Larynx, Lip, Oral Cavity and Pharynx, Liver, Lung, Pancreas, Prostate, Rectum, Small Intestine, Soft Tissue, Stomach, Urinary Bladder
PI: Kim, Richard