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Clinical Trial Search

66 Clinical Trials Found

Clinical Trial 22574

Neoadjuvant and Adjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma
Disease Site: Any Site, Melanoma, skin
PI: Tarhini, Ahmad

Clinical Trial 23240

A Phase 1, Open Label Single-Arm Two-Part Study to Investigate Safety, Pharmacokinetics, and Preliminary Efficacy Of Pan-RAF/MEK Glue NST-628 Oral Tablets in Subjects with Solid Tumors Harboring Genetic Alterations in the MAPK Pathway And With Other Solid Tumors
Disease Site: Any Site
PI: Tarhini, Ahmad

Clinical Trial 23229

An Open-Label Phase 1/2a Clinical Trial to Evaluate the Safety, Immunogenicity, and Preliminary Efficacy of a Lentiviral Vector-Based Therapeutic Vaccine Against Human Papilloma Virus (Lenti-HPV-07) in Participants with HPV-Associated Oropharyngeal Squamous Cell Cancer or Cervical Cancer
Disease Site: Cervix, Head & Neck, Lip, Oral Cavity and Pharynx, Oropharynx
PI: Rabinowits, Guilherme

Clinical Trial 20110

GBM Agile: Global Adaptive Trial Master Protocol
Disease Site: Brain and Nervous System
PI: Grogan, Patrick

Clinical Trial 21970

A multicenter, open-label, first-in human (FIH), multiple expansion cohort, Phase 1/2 study to evaluate the safety and efficacy of DR-01 in adult subjects with large granular lymphocytic leukemia
Disease Site: Lymphoid Leukemia
PI: Sokol, Lubomir

Clinical Trial 23584

A Phase I Dose Finding and Phase II Randomized Trial of Iadademstat Combined with Immune Checkpoint Inhibition Maintenance After Initial Chemoimmunotherapy in Patients with Extensive-Stage Small Cell Lung Cancer
Disease Site: Lung, Small cell lung cancer
PI: Puri, Sonam

Clinical Trial 23590

Disease Site: Other Skin
PI: Rabinowits, Guilherme

Clinical Trial 23697

A Phase 1/1b, Open-label, Multicenter, First-in-human Dose Escalation and Dose Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Anti-tumor Activity of VVD-159642, a RAS-PI3KA Inhibitor, as a Single Agent and in Combination in Participants With Advanced Solid Tumors
Disease Site: Any Site, Breast, Cervix, Corpus Uteri, Esophagus, Lip, Oral Cavity and Pharynx, Lung, Melanoma, skin, Other Digestive Organ, Other Female Genital, Other Skin, Ovary, Pancreas, Prostate, Small Intestine, Stomach
PI: Haura, Eric

Clinical Trial 21341

A Phase II Study of Cemiplimab plus Ziv-Aflibercept for Subjects with Metastatic Uveal Melanoma
Disease Site: Eye and Orbit
PI: Tarhini, Ahmad

Clinical Trial 22256

A Phase 3, Two-stage, Randomized, Multi-center, Controlled, Open-label Study Comparing Iberdomide Maintenance to Lenalidomide Maintenance Treatment after Autologous Stem Cell Transplantation (ASCT) in Participants with Newly Diagnosed Multiple Myeloma (NDMM)
Disease Site: Multiple Myeloma
PI: Alsina, Melissa

Clinical Trial 23766

A First-in-Human Phase 1 Dose Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of FID-022 as Monotherapy in Patients with Advanced Solid Tumors
Disease Site: Anus, Any Site, Breast, Colon, Esophagus, Larynx, Lip, Oral Cavity and Pharynx, Lung, Rectum, Small Intestine, Soft Tissue, Stomach
PI: Rabinowits, Guilherme

Clinical Trial 23912

A Modular, Phase I, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Immunogenicity, Pharmacodynamics, and Preliminary Efficacy of AZD0120, a Dual-targeting Autologous Chimeric Antigen Receptor T-cell (CAR-T) Therapy Directed Against BCMA and CD-19 in Participants with Multiple Myeloma
Disease Site: Bones and Joints
PI: Alsina, Melissa