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Clinical Trial Search

66 Clinical Trials Found

Clinical Trial 23240

A Phase 1, Open Label Single-Arm Two-Part Study to Investigate Safety, Pharmacokinetics, and Preliminary Efficacy Of Pan-RAF/MEK Glue NST-628 Oral Tablets in Subjects with Solid Tumors Harboring Genetic Alterations in the MAPK Pathway And With Other Solid Tumors
Disease Site: Any Site
PI: Tarhini, Ahmad

Clinical Trial 23229

An Open-Label Phase 1/2a Clinical Trial to Evaluate the Safety, Immunogenicity, and Preliminary Efficacy of a Lentiviral Vector-Based Therapeutic Vaccine Against Human Papilloma Virus (Lenti-HPV-07) in Participants with HPV-Associated Oropharyngeal Squamous Cell Cancer or Cervical Cancer
Disease Site: Cervix, Head & Neck, Lip, Oral Cavity and Pharynx, Oropharynx
PI: Rabinowits, Guilherme

Clinical Trial 23448

Disease Site: Anus, Any Site, Colon, Corpus Uteri, Lung, Other Digestive Organ, Pancreas, Rectum
PI: Biachi de Castria, Tiago

Clinical Trial 23599

Phase 1a/1b Open-Label Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of BBO-11818 in Subjects with Advanced KRAS Mutant Cancers
Disease Site: Anus, Any Site, Colon, Lung, Pancreas, Rectum
PI: Haura, Eric

Clinical Trial 21970

A multicenter, open-label, first-in human (FIH), multiple expansion cohort, Phase 1/2 study to evaluate the safety and efficacy of DR-01 in adult subjects with large granular lymphocytic leukemia
Disease Site: Lymphoid Leukemia
PI: Sokol, Lubomir

Clinical Trial 23590

Disease Site: Other Skin
PI: Rabinowits, Guilherme

Clinical Trial 23697

A Phase 1/1b, Open-label, Multicenter, First-in-human Dose Escalation and Dose Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Anti-tumor Activity of VVD-159642, a RAS-PI3KA Inhibitor, as a Single Agent and in Combination in Participants With Advanced Solid Tumors
Disease Site: Any Site, Breast, Cervix, Corpus Uteri, Esophagus, Lip, Oral Cavity and Pharynx, Lung, Melanoma, skin, Other Digestive Organ, Other Female Genital, Other Skin, Ovary, Pancreas, Prostate, Small Intestine, Stomach
PI: Haura, Eric

Clinical Trial 23584

A Phase I Dose Finding and Phase II Randomized Trial of Iadademstat Combined with Immune Checkpoint Inhibition Maintenance After Initial Chemoimmunotherapy in Patients with Extensive-Stage Small Cell Lung Cancer
Disease Site: Lung, Small cell lung cancer
PI: Puri, Sonam

Clinical Trial 21341

A Phase II Study of Cemiplimab plus Ziv-Aflibercept for Subjects with Metastatic Uveal Melanoma
Disease Site: Eye and Orbit
PI: Tarhini, Ahmad

Clinical Trial 22256

A Phase 3, Two-stage, Randomized, Multi-center, Controlled, Open-label Study Comparing Iberdomide Maintenance to Lenalidomide Maintenance Treatment after Autologous Stem Cell Transplantation (ASCT) in Participants with Newly Diagnosed Multiple Myeloma (NDMM)
Disease Site: Multiple Myeloma
PI: Alsina, Melissa

Clinical Trial 23645

A Phase 1 Study of XB628 in Participants With Recurrent Advanced or Metastatic Solid Tumors
Disease Site: Any Site, Cervix, Corpus Uteri, Other Female Genital, Other Male Genital, Other Urinary, Ovary, Prostate, Urinary Bladder
PI: Park, Robin

Clinical Trial 23660

A Phase 1 Study of MOMA-341 as Monotherapy or Combination Therapy in Participants with Advanced or Metastatic Solid Tumors
Disease Site: Anus, Any Site, Colon, Corpus Uteri, Esophagus, Other Digestive Organ, Rectum
PI: Biachi de Castria, Tiago