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Clinical Trial Search

366 Clinical Trials Found

Clinical Trial 22540

A Phase 1, open-label, multicenter, first-in-human study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary anti-tumor activity of VVD-130037, a Kelch-like ECH-associated protein 1 (KEAP1) activator, in participants with advanced solid tumors
Disease Site: Lung
PI: Chiappori, Alberto

Clinical Trial 22002

A Multicenter Open-Label Study of RMC-6236 in Patients with Advanced Solid Tumors Harboring Specific Mutations in RAS
Disease Site: Any Site, Liver, Lung, Other Digestive Organ, Pancreas, Small Intestine, Stomach
PI: Kim, Dae Won

Clinical Trial 22279

A phase 1a/b open-label master study of pf-07799544 as a Single-agent and in combination with other targeted agents In participants with braf-mutant melanoma and other solid Tumors
Disease Site: Melanoma, skin
PI: Eroglu, Zeynep

Clinical Trial 23369

Disease Site: Other
PI: Grogan, Patrick

Clinical Trial 23454

Disease Site: Soft Tissue
PI: Gaballa, Sameh

Clinical Trial 23563

A Phase 1b trial of Teclistamab in Combination with Iberdomide for Relapsed/Refractory Multiple Myeloma
Disease Site: Multiple Myeloma
PI: Grajales-Cruz, Ariel

Clinical Trial 23556

A Phase 1 Study of MLN7243 (TAK-243) for Either Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome/Chronic Myelomonocytic Leukemia Refractory to Hypomethylating Agents
Disease Site: Acute Leukemia (ALL, AML), Myelodysplastic syndrome (MDS)
PI: Lancet, Jeffrey

Clinical Trial 23641

Disease Site: Unknown Sites
PI: Pidala, Joseph

Clinical Trial 23581

A Phase 1b Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Tarlatamab in Combination with YL201 with or without Anti-PD-L1 in Subjects with Extensive Stage Small Cell Lung Cancer
Disease Site: Lung
PI: Puri, Sonam

Clinical Trial 23624

A Phase 1/2 Open-label Study to Investigate the Safety of Sonrotoclax Ramp-up Schedule(s) in Adult Patients With Hematological Malignancies
Disease Site: Soft Tissue
PI: Zhang, Yumeng

Clinical Trial 23659

A Phase 1/2 Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of ARV-806 in Participants With KRAS G12D Mutated Advanced Solid Tumors
Disease Site: Any Site, Cervix, Colon, Corpus Uteri, Lung, Other Female Genital, Pancreas, Rectum
PI: Kim, Richard

Clinical Trial 23777

A Randomized, Masked, Placebo Controlled, Phase II Trial of Concurrent Chemoradiation with BMX-001 in Patients with Head and Neck Squamous Cell Carcinoma Receiving Concurrent Chemoradiation
Disease Site: Larynx, Lip, Oral Cavity and Pharynx
PI: Razavian, Niema