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363 Clinical Trials Found

Clinical Trial 23376

Disease Site: Larynx, Lip, Oral Cavity and Pharynx
PI: Kirtane, Kedar

Clinical Trial 23240

A Phase 1, Open Label Single-Arm Two-Part Study to Investigate Safety, Pharmacokinetics, and Preliminary Efficacy Of Pan-RAF/MEK Glue NST-628 Oral Tablets in Subjects with Solid Tumors Harboring Genetic Alterations in the MAPK Pathway And With Other Solid Tumors
Disease Site: Any Site
PI: Tarhini, Ahmad

Clinical Trial 23229

An Open-Label Phase 1/2a Clinical Trial to Evaluate the Safety, Immunogenicity, and Preliminary Efficacy of a Lentiviral Vector-Based Therapeutic Vaccine Against Human Papilloma Virus (Lenti-HPV-07) in Participants with HPV-Associated Oropharyngeal Squamous Cell Cancer or Cervical Cancer
Disease Site: Cervix, Head & Neck, Lip, Oral Cavity and Pharynx, Oropharynx
PI: Rabinowits, Guilherme

Clinical Trial 23307

A Phase 1/1b, Open-label, Multicenter, Dose Escalation and Dose Expansion Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of KQB198 as Monotherapy and in Combination with Anticancer Agents in Participants with Advanced Hematologic Malignancies
Disease Site: Chronic Leukemia (CLL, CML), Other Hematopoietic
PI: Chan, Onyee

Clinical Trial 20899

Phase I/II Study of Stereotactic Radiation and Abemaciclib with or without Imlunestrant in the Management of Hormone Receptor Positive HER2 Negative Breast Cancer Brain Metastases (STRONG Trial)
Disease Site: Brain and Nervous System, Breast
PI: Ahmed, Kamran

Clinical Trial 21122

A Multicenter, Phase 1, Open-label, Dose-escalation and Expansion Study of AZD0486, a Bispecific Antibody Targeting CD19 in Subjects with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
Disease Site: Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma
PI: Gaballa, Sameh

Clinical Trial 20487

Phase I/II Study of Radiation Therapy Followed by Intrathecal Trastuzumab/Pertuzumab in the Management of HER2+ Breast Leptomeningeal Disease
Disease Site: Brain and Nervous System, Breast, Leptomeningeal (LMD)
PI: Ahmed, Kamran

Clinical Trial 21341

A Phase II Study of Cemiplimab plus Ziv-Aflibercept for Subjects with Metastatic Uveal Melanoma
Disease Site: Eye and Orbit
PI: Tarhini, Ahmad

Clinical Trial 21970

A multicenter, open-label, first-in human (FIH), multiple expansion cohort, Phase 1/2 study to evaluate the safety and efficacy of DR-01 in adult subjects with large granular lymphocytic leukemia
Disease Site: Lymphoid Leukemia
PI: Sokol, Lubomir

Clinical Trial 21955

Disease Site: Non-Hodgkin's Lymphoma
PI: Locke, Frederick

Clinical Trial 21626

A Phase 1, Open-Label, Multicenter Study to Assess Safety, Tolerability, PK, and Efficacy of MK-1084 as Monotherapy and in Combination with Pembrolizumab in Subjects with KRASG12C Mutant Advanced Solid Tumors
Disease Site: Lung
PI: Gray, Jhanelle

Clinical Trial 21997

Adaptive Therapy of Vismodegib in Advanced Basal Cell Carcinoma
Disease Site: Other Skin
PI: Eroglu, Zeynep