Sonam Puri, MD

Cancer Focus:
Lung Cancer

Dr. Puri received her MD degree from Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India. She completed an Internal Medicine Residency at the University of Connecticut School of Medicine, Farmington, followed by a Hematology and Oncology Fellowship at Moffitt Cancer Center, Tampa. Dr. Puri joins us from the Huntsman Cancer Institute at the University of Utah, Salt Lake City, where she was appointed Assistant Professor in the Division of Medical Oncology. During her time at the Huntsman Cancer Institute, she served as the Physician Leader for the Thoracic Clinical Trial Research Group; in that role, she managed the ongoing and future clinical trial portfolio. We are excited for her to partner with Dr. Andreas Saltos in the role of our Clinical Research Medical Director to drive the clinical research vision and manage our trial portfolio.

Dr. Puri’s clinical interests involve treating patients with thoracic malignancies including non-small cell and small cell lung cancer. Her research interests include development of clinical trials for patients with thoracic malignancies with emphasis on immunotherapy, targeted therapy, and other novel therapeutics.

Clinical Trial 23420
A Phase 1/2, First in Human, Dose Escalation and Dose Expansion Study of BHV-1510 (Previously PBI-410) as Monotherapy and in Combination with Anti-Cancer Agents in Participants with Advanced Solid Tumors
Condition: Thoracic
Intervention: BHV-1510 (); Cemiplimab (); REGN2810 (Cemiplimab)
Status: OPEN (SUSPENDED)

Clinical Trial 23578
A Randomized, Double-Blind, Phase 3 Trial of Adagrasib plus Pembrolizumab plus Chemotherapy vs. Placebo plus Pembrolizumab plus Chemotherapy in Participants with Previously Untreated, Locally Advanced or Metastatic Non-squamous Non-small Cell Lung Cancer with KRAS G12C Mutation (KRYSTAL-4)
Condition: Thoracic
Intervention: Adagrasib/Placebo (); Alimta (Pemetrexed); Paraplatin (carboplatin); Pembrolizumab (Keytruda); Pemetrexed (); carboplatin (); cisplatin ()
Status: OPEN (SUSPENDED)

Clinical Trial 23580
A Phase 1/2 Open-Label, Multicenter, First-in-Human Study of the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of BH-30643 in Adult Subjects with Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations (SOLARA)
Condition: Thoracic
Intervention: Alimta (Pemetrexed); BH-30643 (); Paraplatin (carboplatin); Pemetrexed (); carboplatin ()
Status: OPEN (SUSPENDED)

Clinical Trial 23772
A Phase 2/3 Open Label Randomized Study of Telisotuzumab Adizutecan Compared to Standard of Care in Subjects with Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non- Small Cell Lung Cancer After Progression on a Third-Generation EGFR TKI - AndroMETa-Lung-713
Condition: Thoracic
Intervention: AZD9291 (Osimertinib); Alimta (Pemetrexed); Amivantamab (); JNJ-61186372 (Amivantamab); Osimertinib (); Paraplatin (carboplatin); Pemetrexed (); Telisotuzumab Adizutecan (); carboplatin (); cisplatin ()
Status: OPEN (SUSPENDED)

Clinical Trial 23779
A Phase 1/2a Study to Assess Safety, Tolerability, and Efficacy of [212Pb]Pb-DOTAM-MAM279 in Patients with Small Cell Lung Cancer and Other DLL3 Expressing Solid Tumors
Condition: Thoracic
Intervention: [203Pb]Pb-DOTAM-MAM279 (); [212Pb]Pb-DOTAM-MAM279 ()
Status: Open

Clinical Trial 23795
SEZanne: A Phase 2 Randomized, Open label, Multicenter Study to Evaluate the Optimal Dose, Safety, and Efficacy of ABBV-706 in Combination with Atezolizumab versus Standard of Care as First-Line Treatment in Subjects with Previously Untreated Extensive Stage Small Cell Lung Cancer (ES-SCLC)
Condition: Thoracic
Intervention: ABBV-706 (); Atezolizumab (Tecentriq); Etoposide (); PM01183 (lurbinectedin); Paraplatin (carboplatin); carboplatin (); lurbinectedin ()
Status: Open

Clinical Trial 24110
A Phase 1b Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Tarlatamab in Combination with ZL-1310 with or without Anti-PD-L1 in Participants with Small Cell Lung Cancer
Condition: Thoracic
Intervention: AMP-514 (Durvalumab); Durvalumab (); MEDI4736 (Durvalumab); Tarlatamab (AMG 757); ZL-1310 ()
Status: Open

If you believe you are eligible for one of these trials or studies, please call
813-745-6100 or toll-free 1-800-679-0775.

• Puri S, Ismaila N, Azar IH, Freeman-Daily J, Furuya N, Kuruvilla S, Roof L, Velazquez AI, Wang Y, Wheatley Price P, Leighl NB. Therapy for Stage IV Non-Small Cell Lung Cancer With Driver Alterations: ASCO Living Guideline, Version 2026.3.2. J Clin Oncol. 2026 Sep.44(26):e127-e139. Pubmedid: 42372216.
• Digumarthy SR, Messick B, Walker CM, Little BP, Amini A, Batra K, Begnaud A, Brixey AG, Carroll MB, Chelala L, Christensen JD, Cox CW, Kim RY, Lin K, Lui NS, Nagji AS, Puri S, Stowell JT, Ulaner GA, Yanagawa J, Henry TS. ACR Appropriateness Criteria® Indolent Lung Cancer. J Am Coll Radiol. 2026 Oct.23(10):2007-2023. Pubmedid: 42573542. Pmcid: PMC13572971.
• Puri S, Elliott A, Naqash AR, Shukair HA, Kerrigan KC, Patel S, Seeber A, Kocher F, Uprety D, Mamdani H, Kulkarni AA, Lopes G, Halmos B, Borghaei H, Akerley W, Sica GL, Liu SV, Oliver TG, Owonikoko TK. Multiomic characterization of small cell lung cancer: Real-world insights into therapeutic opportunities. Cancer. 2026 Mar.132(5):e70284. Pubmedid: 41761743. Pmcid: PMC12949428.
• Puri S, Leighl NB, Ismaila N, Rous FA, Ahluwalia A, Alluri K, Azar IH, Campbell T, Durm G, Feldman J, Florez N, Freeman-Daily J, Furuya N, Gadgeel S, Halmos B, Horinouchi H, Kuruvilla S, Macvicar GR, Malhotra N, Marrone KA, Mishra DR, Mullane M, Naidoo J, Owen DH, Pellini B, Presley CJ, Qin A, Roof L, Schenk EL, Sequist L, Singh N, Singhi EK, Suga JM, Velazquez AI, Wang Y, Price PW, Reuss JE, Bazhenova L. Therapy for Stage IV Non-Small Cell Lung Cancer With Driver Alterations: ASCO Living Guideline, 2026.3.0. J Clin Oncol. 2026 Mar.44(7):e15-e55. Pubmedid: 41632926.
• Marks JA, Sweeney K, Elliott A, Gupta B, VanderWalde A, Puri S, Shields MD, Nieva JJ, Soares HP, Ma PC, Halmos B, Liu SV. SEZ6 expression and lineage plasticity in small cell lung cancer and transformed non-small cell lung cancer. Lung Cancer. 2026 Mar.213:108913. Pubmedid: 41534317.
• Reuss JE, Bazhenova L, Ismaila N, Abu Rous F, Ahluwalia A, Alluri K, Azar IH, Campbell T, Durm G, Feldman J, Florez N, Freeman-Daily J, Furuya N, Gadgeel S, Halmos B, Horinouchi H, Kuruvilla S, Macvicar GR, Malhotra N, Marrone KA, Mishra DR, Mullane M, Naidoo J, Owen DH, Pellini B, Presley CJ, Qin A, Roof L, Schenk EL, Sequist L, Singh N, Singhi EK, Suga JM, Velazquez AI, Wang Y, Wheatley Price P, Puri S, Leighl NB. Therapy for Stage IV Non-Small Cell Lung Cancer Without Driver Alterations: ASCO Living Guideline, 2026.3.0. J Clin Oncol. 2026 Mar.44(7):e56-e88. Pubmedid: 41632927.
• Joshi U, Ong F, Melzer D, Ma JC, Saltos A, Chiappori A, Creelan B, Pellini B, Lu C, Haura E, Shafique M, Tanvetyanon T, Kareem SS, Budhathoki P, Solarte DCB, Naqvi SMH, Puglianini OC, Gaballa S, Gray JE, Puri S. Optimizing Tarlatamab Delivery in Small Cell and Neuroendocrine Lung Cancer: Real-World Insights into Step-Up Dosing and Prophylactic Tocilizumab Use. Clin Lung Cancer. 2026 Mar.27(2):48-58. Pubmedid: 41544604.
• Reuss JE, Ismaila N, Ahluwalia A, Campbell T, Feldman J, Gadgeel S, Mullane M, Presley CJ, Singhi EK, Suga JM, Puri S. Therapy for Stage IV Non-Small Cell Lung Cancer With Driver Alterations: ASCO Living Guideline, 2026.3.1. J Clin Oncol. 2026 Jun.44(18):e89-e100. Pubmedid: 42190143.
• Ganti AKP, Loo BW, Badiyan S, Bassetti M, Bestvina C, Chiang A, Choudhury N, D'Avella CA, Daly M, Dowlati A, Edelman M, Florsheim C, Gold KA, Goldman JW, Grecula JC, Hann C, Khalil M, Lee R, Malhotra J, Merritt RE, Mohindra N, Molina JR, Moran C, Mulvey C, Osmundson EC, Patel S, Patil T, Pokharel S, Puri S, Qin A, Sands J, Shields M, Tailor TD, Waqar SN, Cassara CJ, Ramakrishnan S. NCCN Guidelines® Insights: Small Cell Lung Cancer, Version 2.2026. J Natl Compr Canc Ne. 2026 Jan.24(1). Pubmedid: 41671459.
• Zhang B, Alder L, Rosner S, Desai A, Cooper AJ, Yimer H, Bogdanska W, Naqash AR, Taylor A, Joshi U, Carlisle J, Champiat S, Altan M, Vega MF, Halm J, Manzano JG, Fenton G, Nie Y, Wang K, Parma M, Rudin CM, Chiang A, Byers LA, Gay CM, Puri S. A multi-institutional perspective on tarlatamab administration and management of CRS/ICANS. Lung Cancer. 2026 Jan.211:108870. Pubmedid: 41371100.
• Cooper AJ, Herzberg B, Parma M, Wang K, Alder L, Weber UM, Patil T, Joshi U, Puri S, Saqi A, Clark P, Gay CM, Cascone T, Singhi EK, Blumenschein G, Skoulidis F, Tu J, Stinchcombe TE, Rudin CM, Shu CA, Byers LA, Yu H, Zhang B. Multi-Institution Analysis of Tarlatamab for the Treatment of EGFR-Mutant Transformed Small Cell Lung Cancer. JCO Precis Oncol. 2025 Oct.9:e2500538. Pubmedid: 41166675.
• Ireland AS, Xie DA, Hawgood SB, Barbier MW, Zuo LY, Hanna BE, Lucas-Randolph S, Tyson DR, Witt BL, Govindan R, Dowlati A, Moser JC, Thomas A, Puri S, Rudin CM, Chan JM, Elliott A, Oliver TG. Basal cell of origin resolves neuroendocrine-tuft lineage plasticity in cancer. Nature. 2025 Nov.647(8088):257-267. Pubmedid: 40963028. Pmcid: PMC12589105.
• da Silva IP, Zimmer L, Blay JY, Maio M, Larkin J, Grimm MO, Puri S, Butler MO, Patel S, Thakkar PK, Long GV, Melero I. Retreatment, rechallenge, and escalation with subsequent immune checkpoint inhibitor therapies across cancers after initial failure. ESMO Open. 2025 Nov.10(11):105833. Pubmedid: 41202502. Pmcid: PMC12639429.
• Fenlon J, Van Bibber N, Mahlow J, Yamoah K, Soupir AC, Nguyen JV, Moran Segura C, Spivak AM, Knudsen BS, Zhou Q, Hu-Lieskovan S, Puri S, Zhang W, DeRose YS, Suneja G, Coghill AE. Human Immunodeficiency Virus-Associated Differences in the Tumor Immune Microenvironment of Lung, Breast, and Prostate Cancers. Cancer Epidemiol Biomarkers Prev. 2025 Jun.34(6):860-867. Pubmedid: 40183760. Pmcid: PMC12133412.
• Jo Y, Puri S, Haaland B, Coletta AM, Chipman JJ, Embrey K, Kerrigan KC, Patel SB, Moynahan K, Gumbleton M, Akerley WL. Augmenting Prognostication: Utilizing Activity Trackers to Enhance Survival Prediction in Metastatic Non-Small Cell Lung Cancer. Clin Lung Cancer. 2025 Jan.26(1):29-38. Pubmedid: 39572323.
• Sen T, Dotsu Y, Corbett V, Puri S, Sen U, Boyle TA, Mack P, Hirsch F, Aljumaily R, Naqash AR, Sukrithan V, Karim NA. Pulmonary neuroendocrine neoplasms: the molecular landscape, therapeutic challenges, and diagnosis and management strategies. Lancet Oncol. 2025 Jan.26(1):e13-e33. Pubmedid: 39756451.
• Coletta AM, Lee H, Puri S, Culleton S, Covington MF, Yap JT, Maslana KE, Haaland B, Akerley W. The Association Between Body Composition, Overall Survival, Treatment Decisions, and Patient-Reported Outcomes in Metastatic Non-Small-Cell Lung Cancer. Cancer Med. 2025 Jan.14(1):e70534. Pubmedid: 39764691.
• Marin-Acevedo JA, Thapa R, Bandikatla SV, Chen DT, Hicks JK, Gray JE, Puri S. Outcomes with frontline immune checkpoint inhibitors among individuals with BRAF-mutant non-small cell lung cancer. Front Oncol. 2025 Dec.15:1681119. Pubmedid: 41450930. Pmcid: PMC12727587.
• Kirtane K, Puri S, Chung CH. Durable Complete Response of a Delta-Like Ligand 3 Expressing Head and Neck Neuroendocrine Carcinoma to Tarlatamab. JCO Precis Oncol. 2025 Dec.9:e2500806. Pubmedid: 41370728.
• Owen DH, Halmos B, Puri S, Qin A, Ismaila N, Abu Rous F, Alluri K, Freeman-Daily J, Malhotra N, Marrone KA, Bazhenova L. Therapy for Stage IV Non-Small Cell Lung Cancer Without Driver Alterations: ASCO Living Guideline, Version 2025.1. J Clin Oncol. 2025 Aug.43(24):e45-e58. Pubmedid: 40674687.
• Neal JW, Santoro A, Gonzalez-Cao M, Lim FL, Fang B, Gentzler RD, Goldschmidt J, Khrizman P, Proto C, Patel S, Puri S, Liu SV, Massarelli E, Williamson D, Schwickart M, Scheffold C, Andrianova S, Felip E. Cabozantinib Plus Atezolizumab or Cabozantinib Alone in Patients With Advanced NSCLC Previously Treated With an Immune Checkpoint Inhibitor: Results From the Phase 1b COSMIC-021 Study. JTO Clin Res Rep. 2024 Oct.5(10):100666. Pubmedid: 39318387. Pmcid: PMC11421317.
• Ireland AS, Hawgood SB, Xie DA, Barbier MW, Lucas-Randolph S, Tyson DR, Zuo LY, Witt BL, Govindan R, Dowlati A, Moser JC, Puri S, Rudin CM, Chan JM, Elliott A, Oliver TG. Basal cell of origin resolves neuroendocrine-tuft lineage plasticity in cancer. bioRxiv. 2024 Nov. Pubmedid: 39605338. Pmcid: PMC11601426.
• Morgensztern D, Ready N, Johnson ML, Dowlati A, Choudhury N, Carbone DP, Schaefer E, Arnold SM, Puri S, Piotrowska Z, Hegde A, Chiang AC, Iams W, Tolcher A, Nosaki K, Kozuki T, Li T, Santana-Davila R, Akamatsu H, Murakami H, Yokouchi H, Wang S, Zha J, Li R, Robinson RR, Hingorani P, Jeng EE, Furqan M. A Phase I First-in-Human Study of ABBV-011, a Seizure-Related Homolog Protein 6-Targeting Antibody-Drug Conjugate, in Patients with Small Cell Lung Cancer. Clin Cancer Res. 2024 Nov.30(22):5042-5052. Pubmedid: 39287821. Pmcid: PMC11565168.
• Wang X, Lee H, Haaland B, Kerrigan K, Puri S, Akerley W, Shen J. A matching-based machine learning approach to estimating optimal dynamic treatment regimes with time-to-event outcomes. Stat Methods Med Res. 2024 May.33(5):794-806. Pubmedid: 38502008.
• Owen DH, Jaiyesimi IA, Leighl NB, Ismaila N, Florez N, Puri S, Schenk EL, Schneider BJ, Patel JD. Therapy for Stage IV Non-Small Cell Lung Cancer With and Without Driver Alterations: ASCO Living Guideline Clinical Insights. JCO Oncol Pract. 2024 Jul.20(7):893-898. Pubmedid: 38588478.
• Kuboki Y, Fakih M, Strickler J, Yaeger R, Masuishi T, Kim EJ, Bestvina CM, Kopetz S, Falchook GS, Langer C, Krauss J, Puri S, Cardona P, Chan E, Varrieur T, Mukundan L, Anderson A, Tran Q, Hong DS. Sotorasib with panitumumab in chemotherapy-refractory KRASG12C-mutated colorectal cancer: a phase 1b trial. Nat Med. 2024 Jan.30(1):265-270. Pubmedid: 38177853. Pmcid: PMC11135132.
• Puri S, Malani R, Chalmers A, Kerrigan K, Patel SB, Monynahan K, Cannon L, Blouw B, Akerley W. Keeping a track on leptomeningeal disease in non-small cell lung cancer: A single-institution experience with CNSideTM. Neurooncol Adv. 2024 Jan.6(1):vdad150. Pubmedid: 38196737. Pmcid: PMC10776200.
• Bazhenova L, Ismaila N, Abu Rous F, Alluri K, Freeman-Daily J, Halmos B, Malhotra N, Marrone KA, Puri S, Qin A, Leighl NB. Therapy for Stage IV Non-Small Cell Lung Cancer With Driver Alterations: ASCO Living Guideline, Version 2024.2. J Clin Oncol. 2024 Dec.42(36):e72-e86. Pubmedid: 39531596.
• Sen T, Takahashi N, Chakraborty S, Takebe N, Nassar AH, Karim NA, Puri S, Naqash AR. Emerging advances in defining the molecular and therapeutic landscape of small-cell lung cancer. Nat Rev Clin Oncol. 2024 Aug.21(8):610-627. Pubmedid: 38965396.
• Bodor JN, Patel JD, Wakelee HA, Levy BP, Borghaei H, Pellini B, Costello MR, Dowell JE, Finley G, Huang CH, Neal JW, Nieva JJ, Puri S, Socinski MA, Thomas C, Ross EA, Litwin S, Clapper ML, Treat J. Phase II Randomized Trial of Carboplatin, Pemetrexed, and Bevacizumab With and Without Atezolizumab in Stage IV Nonsquamous Non-Small-Cell Lung Cancer Patients Who Harbor a Sensitizing EGFR Mutation or Have Never Smoked. Clin Lung Cancer. 2023 Nov.24(7):e242-e246. Pubmedid: 37451930. Pmcid: PMC11476834.
• Sama S, Kerrigan K, Sinnott JA, Puri S, Akerley W, Haaland B, Patel S. Real-world comparison of survival outcomes with cisplatin versus carboplatin in patients with limited-stage small-cell lung cancer. Cancer Treat Res Commun. 2023 May.35:100686. Pubmedid: 36736060.
• Smith JT, Puri S, Akerley W. Brief Report: EGFR L833V/H835L Duplex-Mutated NSCLC With Leptomeningeal Carcinomatosis Responsive to Osimertinib. Clin Lung Cancer. 2023 Jun.24(4):360-361. Pubmedid: 36935243.
• Cannon-Albright LA, Teerlink CC, Stevens J, Facelli JC, Carr SR, Allen-Brady K, Puri S, Bailey-Wilson JE, Musolf AM, Akerley W. A rare FGF5 candidate variant (rs112475347) for predisposition to nonsquamous, nonsmall-cell lung cancer. Int J Cancer. 2023 Jul.153(2):364-372. Pubmedid: 36916144. Pmcid: PMC10182245.
• El Zarif T, Nassar AH, Adib E, Fitzgerald BG, Huang J, Mouhieddine TH, Rubinstein PG, Nonato T, McKay RR, Li M, Mittra A, Owen DH, Baiocchi RA, Lorentsen M, Dittus C, Dizman N, Falohun A, Abdel-Wahab N, Diab A, Bankapur A, Reed A, Kim C, Arora A, Shah NJ, El-Am E, Kozaily E, Abdallah W, Al-Hader A, Abu Ghazal B, Saeed A, Drolen C, Lechner MG, Drakaki A, Baena J, Nebhan CA, Haykal T, Morse MA, Cortellini A, Pinato DJ, Dalla Pria A, Hall E, Bakalov V, Bahary N, Rajkumar A, Mangla A, Shah V, Singh P, Aboubakar Nana F, Lopetegui-Lia N, Dima D, Dobbs RW, Funchain P, Saleem R, Woodford R, Long GV, Menzies AM, Genova C, Barletta G, Puri S, Florou V, Idossa D, Saponara M, Queirolo P, Lamberti G, Addeo A, Bersanelli M, Freeman D, Xie W, Reid EG, Chiao EY, Sharon E, Johnson DB, Ramaswami R, Bower M, Emu B, Marron TU, Choueiri TK, Baden LR, Lurain K, Sonpavde GP, Naqash AR. Safety and Activity of Immune Checkpoint Inhibitors in People Living With HIV and Cancer: A Real-World Report From the Cancer Therapy Using Checkpoint Inhibitors in People Living With HIV-International (CATCH-IT) Consortium. J Clin Oncol. 2023 Jul.41(21):3712-3723. Pubmedid: 37192435. Pmcid: PMC10351941.
• Burns L, Hsu CY, Whisenant JG, Marmarelis ME, Presley CJ, Reckamp KL, Khan H, Jo Fidler M, Bestvina CM, Brahmer J, Puri S, Patel JD, Halmos B, Hirsch FR, Liu SV, Costa DB, Goldberg SB, Feldman LE, Mamdani H, Puc M, Mansfield AS, Islam N, Scilla KA, Garassino MC, Horn L, Peters S, Wakelee HA, Charlot M, Tapan U. Disparities in outcomes between Black and White patients in North America with thoracic malignancies and COVID-19 infection (TERAVOLT). Lung Cancer. 2023 Dec.186:107423. Pubmedid: 37995456.
• Puri S, Saltos AN, Gray JE. Race-inclusive and equitable access to immune checkpoint inhibitor therapy: What are the biggest hurdles?. Cancer. 2023 Dec.129(23):3692-3693. Pubmedid: 37728029.
• Florou V, Floudas CS, Maoz A, Naqash AR, Norton C, Tan AC, Sokol ES, Frampton G, Soares HP, Puri S, Swami U, Wilky B, Hosein P, Trent J, Lopes GL, Park W, Garrido-Laguna I. Real-world pan-cancer landscape of frameshift mutations and their role in predicting responses to immune checkpoint inhibitors in cancers with low tumor mutational burden. J Immunother Cancer. 2023 Aug.11(8). Pubmedid: 37586768. Pmcid: PMC10432623.
• Whisenant JG, Baena J, Cortellini A, Huang LC, Lo Russo G, Porcu L, Wong SK, Bestvina CM, Hellmann MD, Roca E, Rizvi H, Monnet I, Boudjemaa A, Rogado J, Pasello G, Leighl NB, Arrieta O, Aujayeb A, Batra U, Azzam AY, Unk M, Azab MA, Zhumagaliyeva AN, Gomez-Martin C, Blaquier JB, Geraedts E, Mountzios G, Serrano-Montero G, Reinmuth N, Coate L, Marmarelis M, Presley CJ, Hirsch FR, Garrido P, Khan H, Baggi A, Mascaux C, Halmos B, Ceresoli GL, Fidler MJ, Scotti V, Métivier AC, Falchero L, Felip E, Genova C, Mazieres J, Tapan U, Brahmer J, Bria E, Puri S, Popat S, Reckamp KL, Morgillo F, Nadal E, Mazzoni F, Agustoni F, Bar J, Grosso F, Avrillon V, Patel JD, Gomes F, Ibrahim E, Trama A, Bettini AC, Barlesi F, Dingemans AM, Wakelee H, Peters S, Horn L, Garassino MC, Torri V. A Definitive Prognostication System for Patients With Thoracic Malignancies Diagnosed With Coronavirus Disease 2019: An Update From the TERAVOLT Registry. J Thorac Oncol. 2022 May.17(5):661-674. Pubmedid: 35121086. Pmcid: PMC8804493.
• Kerrigan K, Jo Y, Chipman J, Haaland B, Puri S, Akerley W, Patel S. A Real-World Analysis of the Use of Systemic Therapy in Malignant Pleural Mesothelioma and the Differential Impacts on Overall Survival by Practice Pattern. JTO Clin Res Rep. 2022 Mar.3(3):100280. Pubmedid: 35243411. Pmcid: PMC8861643.
• Kerrigan K, Puri S. Role of CTLA Inhibition in Management of Non-Small Cell Lung Cancer. Curr Oncol Rep. 2022 Jan.24(1):113-123. Pubmedid: 35060001.
• Wang X, Kerrigan K, Puri S, Shen J, Akerley W, Haaland B. Dynamic Prediction of Near-Term Overall Survival in Patients with Advanced NSCLC Based on Real-World Data. Cancers (Basel). 2022 Jan.14(3). Pubmedid: 35158958. Pmcid: PMC8833771.
• Higgins KA, Puri S, Gray JE. Systemic and Radiation Therapy Approaches for Locally Advanced Non-Small-Cell Lung Cancer. J Clin Oncol. 2022 Feb.40(6):576-585. Pubmedid: 34985931.
• Nagasaka M, Asad MFB, Al Hallak MN, Uddin MH, Sukari A, Baca Y, Xiu J, Magee D, Mamdani H, Uprety D, Kim C, Xia B, Liu SV, Nieva JJ, Lopes G, Bepler G, Borghaei H, Demeure MJ, Raez LE, Ma PC, Puri S, Korn WM, Azmi AS. Impact of XPO1 mutations on survival outcomes in metastatic non-small cell lung cancer (NSCLC). Lung Cancer. 2021 Oct.160:92-98. Pubmedid: 34482103. Pmcid: PMC8853639.
• Florou V, Puri S, Garrido-Laguna I, Wilky BA. Considerations for immunotherapy in patients with cancer and comorbid immune dysfunction. Ann Transl Med. 2021 Jun.9(12):1035. Pubmedid: 34277835. Pmcid: PMC8267318.
• Naqash AR, Kihn-Alarcón AJ, Stavraka C, Kerrigan K, Maleki Vareki S, Pinato DJ, Puri S. The role of gut microbiome in modulating response to immune checkpoint inhibitor therapy in cancer. Ann Transl Med. 2021 Jun.9(12):1034. Pubmedid: 34277834. Pmcid: PMC8267312.
• Bindal P, Gray JE, Boyle TA, Florou V, Puri S. Biomarkers of therapeutic response with immune checkpoint inhibitors. Ann Transl Med. 2021 Jun.9(12):1040. Pubmedid: 34277840. Pmcid: PMC8267267.
• Kerrigan K, Wang X, Haaland B, Adamson B, Patel S, Puri S, Akerley W. Real World Characterization of Advanced Non-Small Cell Lung Cancer in Never Smokers by Actionable Mutation Status. Clin Lung Cancer. 2021 Jul.22(4):260-267.e2. Pubmedid: 33678584.
• Kulkarni AA, Naqash AR, Puri S, Dienstmann R. Is It Time to Implement Adjuvant Targeted Therapy in EGFR-Mutant Non-Small-Cell Lung Cancer?. JCO Precis Oncol. 2021 Feb.5. Pubmedid: 34109281. Pmcid: PMC8177880.
• Hsu R, Baca Y, Xiu J, Wang R, Bodor JN, Kim C, Khan H, Mamdani H, Nagasaka M, Puri S, Liu SV, Korn WM, Nieva JJ. Molecular characterization of Kita-Kyushu lung cancer antigen (KK-LC-1) expressing carcinomas. Oncotarget. 2021 Dec.12(25):2449-2458. Pubmedid: 34917263. Pmcid: PMC8664394.
• Ganti AKP, Loo BW, Bassetti M, Blakely C, Chiang A, D'Amico TA, D'Avella C, Dowlati A, Downey RJ, Edelman M, Florsheim C, Gold KA, Goldman JW, Grecula JC, Hann C, Iams W, Iyengar P, Kelly K, Khalil M, Koczywas M, Merritt RE, Mohindra N, Molina J, Moran C, Pokharel S, Puri S, Qin A, Rusthoven C, Sands J, Santana-Davila R, Shafique M, Waqar SN, Gregory KM, Hughes M. Small Cell Lung Cancer, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Ne. 2021 Dec.19(12):1441-1464. Pubmedid: 34902832. Pmcid: PMC10203822.
• Puri S, Lok BH, Leighl N, Gray JE. Editorial: Update on the Biology, Management, and Treatment of Small Cell Lung Cancer. Front Oncol. 2020 Nov.10:1783. Pubmedid: 33282719. Pmcid: PMC7705219.
• Puri S, Saltos A, Perez B, Le X, Gray JE. Locally Advanced, Unresectable Non-Small Cell Lung Cancer. Curr Oncol Rep. 2020 Mar.22(4):31. Pubmedid: 32140986.
• Ireland AS, Micinski AM, Kastner DW, Guo B, Wait SJ, Spainhower KB, Conley CC, Chen OS, Guthrie MR, Soltero D, Qiao Y, Huang X, Tarapcsák S, Devarakonda S, Chalishazar MD, Gertz J, Moser JC, Marth G, Puri S, Witt BL, Spike BT, Oliver TG. MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine Fate. Cancer Cell. 2020 Jul.38(1):60-78.e12. Pubmedid: 32473656. Pmcid: PMC7393942.
• Puri S, Shafique M. Combination checkpoint inhibitors for treatment of non-small-cell lung cancer: an update on dual anti-CTLA-4 and anti-PD-1/PD-L1 therapies. Drugs Context. 2020 Jan.9. Pubmedid: 32158484. Pmcid: PMC7048109.
• Puri S, Holle LM, Forouhar FA, Clement JM. Subcutaneous metastasis from recurrent basaloid squamous cell carcinoma of the esophagus. J Oncol Pharm Pract. 2019 Mar.25(2):492-496. Pubmedid: 29078709.
• Sandoval-Sus JD, Faramand R, Chavez J, Puri S, Parra P, Sokol L, Kharfan-Dabaja MA, Shah B, Ayala E. Allogeneic hematopoietic cell transplantation is potentially curative in mantle cell lymphoma: results from a single institution study. Leuk Lymphoma. 2019 Feb.60(2):309-316. Pubmedid: 29963932.
• Puri S, Shafique M, Gray JE. Immune Checkpoint Inhibitors in Early-Stage and Locally Advanced Non-Small Cell Lung Cancer. CURR TREAT OPTION ON. 2018 Jun.19(8):39. Pubmedid: 29931587.
• Le X, Puri S, Negrao MV, Nilsson M, Robichaux JP, Boyle TA, Hicks JK, Lovinger K, Roarty EB, Rinsurongkawong W, Tang M, Sun H, Elamin YY, Lacerda L, Lewis J, Lee JJ, Roth JA, Swisher SG, Zhang J, William WN, Glisson BS, Papadimitrakopoulou VA, Gray JE, Heymach JV. Landscape of EGFR-Dependent and -Independent Resistance Mechanisms to Osimertinib and Continuation Therapy Beyond Progression in EGFR-Mutant NSCLC. Clin Cancer Res. 2018 Dec.24(24):6195-6203. Pubmedid: 30228210. Pmcid: PMC6295279.
• Puri S, Hyland KA, Weiss KC, Bell GC, Gray JE, Kim R, Lin HY, Hoogland AI, Gonzalez BD, Nelson AM, Kinney AY, Fischer SM, Li D, Jacobsen PB, McLeod HL, Jim HSL. Prediction of chemotherapy-induced nausea and vomiting from patient-reported and genetic risk factors. Support Care Cancer. 2018 Aug.26(8):2911-2918. Pubmedid: 29546524. Pmcid: PMC6200138.
• Puri S, Chatwal M, Gray JE. Anti PD-L1 combined with other agents in non-small cell lung cancer: combinations with non-immuno-oncology agents. Expert Rev Respir Med. 2017 Oct.11(10):791-805. Pubmedid: 28786318.
• Puri S, Markowitz J. The use of baseline biomarkers to predict outcome in melanoma patients treated with pembrolizumab. Ann Res Hosp. 2017 May.1. Pubmedid: 31460494. Pmcid: PMC6711479.
• Puri R, Puri S, Rajani A. Letter by Puri et al Regarding Article, "Reductions in Atherogenic Lipids and Major Cardiovascular Events: A Pooled Analysis of 10 ODYSSEY Trials Comparing Alirocumab With Control". Circulation. 2017 May.135(19):e1039-e1040. Pubmedid: 28483838.
• Gupta T, Parikh K, Puri S, Agrawal S, Agrawal N, Sharma D, DeLorenzo L. The forgotten disease: Bilateral lemierre's disease with mycotic aneurysm of the vertebral artery. Am J Case Rep. 2014 May.15:230-234. Pubmedid: 24883173. Pmcid: PMC4038640.
• Phatak P, Khanagavi J, Aronow WS, Puri S, Yusuf Y, Puccio C. Pericardial synovial sarcoma: challenges in diagnosis and management. F1000Res. 2014 Jan.3:15. Pubmedid: 24715974. Pmcid: PMC3954165.

• Title: S2503: A Randomized Phase II Study of Atezolizumab and JBI-802 Versus Investigator’s Choice of Standard of Care for Previously Treated Extensive Stage Small Cell Lung Cancer
  Award Number: S2503
  Sponsor: HOPE FOUNDATION
  Gray, J. (), Puri, S. (PD/PI)