Vaibhav Chumbalkar, MD

Dr. Chumbalkar received his MD from B.J. Medical College, University of Pune, India. He completed an Anatomic and Clinical Pathology residency at Albany Medical College followed by a Surgical Pathology fellowship at the University of Illinois, Chicago. Most recently he completed a Genitourinary Pathology fellowship at the University of Chicago. Dr. Chumbalkar’s clinical interests are tumors of the central nervous system and the genitourinary tract, including that of kidney, urinary bladder, ureter, urethra, prostate, and testis. His research interests are characterization and classification of kidney tumors, stratification of urothelial tumors, and identification of predictive, and prognostic markers.

• Glushko T, Chumbalkar V, Honarmand AR, Araujo C, McGettigan M, Jeong D. Adrenal hemangiomas versus adrenal pheochromocytomas with radiologic-pathologic correlation. Eur J Radiol. 2025 Jul.188:112122. Pubmedid: 40318501.
• Waqas A, Khan A, Ozturk ZG, Saeed-Vafa D, Chen W, Dhillon J, Bychkov A, Bui MM, Ullah E, Khalil F, Chumbalkar V, Jameel Z, Bittar HT, Singh RS, Parwani AV, Schabath MB, Rasool G. REASONING BEYOND ACCURACY: EXPERT EVALUATION OF LARGE LANGUAGE MODELS IN DIAGNOSTIC PATHOLOGY. medRxiv. 2025 Apr. Pubmedid: 40297448. Pmcid: PMC12036407.
• Wei Z, Iluppangama M, Qi J, Choi JW, Yu A, Gage K, Chumbalkar V, Dhillon J, Balaji KC, Venkataperumal S, Hernandez DJ, Park J, Yedjou C, Alo R, Gatenby RA, Pow-Sang J, Balagurunanthan Y. Quantitative DCE Dynamics on Transformed MR Imaging Discriminates Clinically Significant Prostate Cancer. Cancer Control. 2024 Jan.31. Pubmedid: 39545376. Pmcid: PMC11565616.
• David J, Chumbalkar V, Chadha J. An insight into metastatic Leydig cell tumors: A case report. SAGE Open Med Case Rep. 2023 Jul.11. Pubmedid: 37434893. Pmcid: PMC10331185.
• Chumbalkar V, Wang P, Paner GP. Spectrum of biphasic renal cell carcinomas with hyalinized stroma and psammoma bodies associated and not associated with NF2 alteration. Hum Pathol. 2022 Mar.121:11-18. Pubmedid: 34929230.
• Saoud R, Kristof TW, Judge C, Chumbalkar V, Antic T, Eggener S, Modi P. Clinical and pathological features of renal epithelioid angiomyolipoma (PEComa): A single institution series. Urol Oncol. 2022 Feb.40(2):18-24. Pubmedid: 34815169.
• Howe AS, Pearce J, Lian F, Ribbons L, Chumbalkar V, Nazeer T, Kogan BA. A Case of Ewing Sarcoma of the Bladder Presenting in Early Infancy. J Pediat Hematol Onc. 2021 May.43(4):e478-e480. Pubmedid: 33625095.
• Chumbalkar V, Zagaja G, Montironi R, Paner GP. Seminal vesicle cystadenoma with dysplasia: missing link to adenocarcinoma?. Histopathology. 2021 Aug.79(2):274-276. Pubmedid: 33783025.
• MacDonell J, Patel N, Fischer G, Burdette EC, Qian J, Chumbalkar V, Ghoshal G, Heffter T, Williams E, Gounis M, King R, Thibodeau J, Bogdanov G, Brooks OW, Langan E, Hwang R, Pilitsis JG. Robotic Assisted MRI-Guided Interventional Interstitial MR-Guided Focused Ultrasound Ablation in a Swine Model. Neurosurgery. 2019 May.84(5):1138-1148. Pubmedid: 29905844. Pmcid: PMC6500887.
• Chumbalkar V, Fu Z, Boguniewicz A, Singh TP, Lee H. Gastric Lipohyperplasia Presenting as Gastric Polyposis: the First Case Report and Morphometric Study of Additional 127 Bariatric Specimens with a Proposal for Diagnostic Criteria. Obes Surg. 2019 Jun.29(6):1805-1809. Pubmedid: 30737763.
• Zuo C, Chumbalkar V, Ells PF, Bonville DJ, Lee H. Prevalence of histological features of idiopathic noncirrhotic portal hypertension in general population: a retrospective study of incidental liver biopsies. Hepatol Int. 2017 Sep.11(5):452-460. Pubmedid: 28597108.
• Chumbalkar V, Jennings TA, Ainechi S, Lee EC, Lee H. Extramammary Paget's Disease of Anal Canal Associated With Rectal Adenoma Without Invasive Carcinoma. Gastroenterology Res. 2016 Dec.9(6):99-102. Pubmedid: 28058078. Pmcid: PMC5191897.
• Garnett J, Chumbalkar V, Vaillant B, Gururaj AE, Hill KS, Latha K, Yao J, Priebe W, Colman H, Elferink LA, Bogler O. Regulation of HGF expression by ΔEGFR-mediated c-Met activation in glioblastoma cells. Neoplasia. 2013 Jan.15(1):73-84. Pubmedid: 23359207. Pmcid: PMC3556940.
• Latha K, Li M, Chumbalkar V, Gururaj A, Hwang Y, Dakeng S, Sawaya R, Aldape K, Cavenee WK, Bogler O, Furnari FB. Nuclear EGFRvIII-STAT5b complex contributes to glioblastoma cell survival by direct activation of the Bcl-XL promoter. Int J Cancer. 2013 Feb.132(3):509-520. Pubmedid: 22729867. Pmcid: PMC3802533.
• Hwang Y, Chumbalkar V, Latha K, Bogler O. Forced dimerization increases the activity of ΔEGFR/EGFRvIII and enhances its oncogenicity. Mol Cancer Res. 2011 Sep.9(9):1199-1208. Pubmedid: 21775422. Pmcid: PMC3175255.
• Chumbalkar V, Latha K, Hwang Y, Maywald R, Hawley L, Sawaya R, Diao L, Baggerly K, Cavenee WK, Furnari FB, Bogler O. Analysis of phosphotyrosine signaling in glioblastoma identifies STAT5 as a novel downstream target of ΔEGFR. J Proteome Res. 2011 Mar.10(3):1343-1352. Pubmedid: 21214269. Pmcid: PMC3049961.
• Gwak HS, Shingu T, Chumbalkar V, Hwang YH, DeJournett R, Latha K, Koul D, Alfred Yung WK, Powis G, Farrell NP, Bögler O. Combined action of the dinuclear platinum compound BBR3610 with the PI3-K inhibitor PX-866 in glioblastoma. Int J Cancer. 2011 Feb.128(4):787-796. Pubmedid: 20473884. Pmcid: PMC2990813.
• Chumbalkar V, Sawaya R, Bogler O. Proteomics: the new frontier also for brain tumor research. Curr Prob Cancer. 2008 May.32(3):143-154. Pubmedid: 18501776.
• Chumbalkar VC, Subhashini C, Dhople VM, Sundaram CS, Jagannadham MV, Kumar KN, Srinivas PN, Mythili R, Rao MK, Kulkarni MJ, Hegde S, Hegde AS, Samual C, Santosh V, Singh L, Sirdeshmukh R. Differential protein expression in human gliomas and molecular insights. Proteomics. 2005 Mar.5(4):1167-1177. Pubmedid: 15759318.