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6 Clinical Trials Found

Clinical Trial 21131

A Phase II Randomized Trial of Adjuvant Therapy with Pembrolizumab After Resection of Recurrent/Second Primary Head and Neck Squamous Cell Carcinoma with High Risk Features
Disease Site: Larynx, Lip, Oral Cavity and Pharynx, Head & Neck
PI: Kirtane, Kedar

Clinical Trial 23229

An Open-Label Phase 1/2a Clinical Trial to Evaluate the Safety, Immunogenicity, and Preliminary Efficacy of a Lentiviral Vector-Based Therapeutic Vaccine Against Human Papilloma Virus (Lenti-HPV-07) in Participants with HPV-Associated Oropharyngeal Squamous Cell Cancer or Cervical Cancer
Disease Site: Cervix, Head & Neck, Lip, Oral Cavity and Pharynx, Oropharynx
PI: Rabinowits, Guilherme

Clinical Trial 23298

A Phase 2/3, Randomized, Double-Blind, Controlled Study of Zanzalintinib (XL092) in Combination with Pembrolizumab Vs Pembrolizumab in the First-Line Treatment Of Subjects with PD-L1 Positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
Disease Site: Head & Neck, Larynx, Lip, Oral Cavity and Pharynx, Squamous Cell Carcinoma (SCC)
PI: Rabinowits, Guilherme

Clinical Trial 21641

First-in-Human, Phase 1/1b, Open-label, Multicenter Study of Bifunctional EGFR/TGF_ Fusion Protein BCA101 Alone and in Combination with Pembrolizumab in Patients With EGFR-Driven Advanced Solid Tumors
Disease Site: Colon, Colorectal, Head & Neck, Larynx, Lip, Oral Cavity and Pharynx, Mouth, lip, Rectum
PI: Chung, Christine

Clinical Trial 21657

Randomized Phase II/III Trial of Radiation with High-Dose Cisplatin (100 mg/m2) Every Three Weeks Versus Radiation with Low-Dose Weekly Cisplatin (40 mg/m2) for Patients with Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Disease Site: Head & Neck, Larynx, Lip, Oral Cavity and Pharynx, Mouth, lip
PI: Chung, Christine

Clinical Trial 17425

Randomized Phase II/III Trial of Adjuvant Radiation Therapy with Cisplatin, Docetaxel-Cetuximab, or Cisplatin-Atezolizumab in Pathologic High-Risk Squamous Cell Cancer of the Head and Neck
Disease Site: Larynx, Lip, Oral Cavity and Pharynx, Head & Neck, Mouth, lip
PI: Caudell, Jimmy