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New research from Moffitt Cancer Center suggests a simple way to potentially boost your chances of catching two common cancers early: getting screened for hepatitis C, which can cause liver cancer, and colorectal cancer simultaneously. This dual screening approach might be especially helpful for those born between 1945 and 1965, a group with a higher risk for both cancers.

The first study, led by Shannon Christy, PhD, and Clement Gwede, PhD, surveyed 50 participants from community health centers in Florida to understand the factors influencing the completion of hepatitis C and colorectal cancer screenings. The findings revealed that only 30% of participants had completed both screenings despite the critical importance of early detection.

 

headshot of Dr. Shannon Christy

Shannon Christy, PhD

“The aim of this line of research, which bundles these screening tests together, is to enhance awareness and uptake, potentially reducing cancer incidence and mortality rates,” said Christy, principal investigator of the study.

Hepatitis C virus is a major cause of liver cancer, but the viral infection can be effectively treated. Screening — which is a blood test — is critical, as many with hepatitis C do not know they are infected.

Colorectal cancer is one of the leading causes of cancer death in the United States, but it is highly treatable when caught in its early stages. The Centers for Disease Control and Prevention recommend regular colorectal cancer screenings for those ages 45 to 75 and a one-time hepatitis C virus screening for adults ages 18 to 79.

The completed Moffitt study identified several factors influencing screening uptake. Having a provider recommendation was significantly associated with completing both screening tests. Participants with higher educational attainment and health insurance were more likely to have completed both screenings. Those born in the U.S. also had higher screening rates. Additionally, higher scores in salience and coherence — the belief that screenings make sense and are beneficial — were associated with increased screening completion.

“Understanding these barriers and facilitators helps us tailor our interventions to be more effective,” Christy said. “Education, provider recommendation and access are crucial. By addressing these areas, we can improve screening rates and health outcomes for all.”

Christy and Gwede recently received funding from the Florida Department of Health’s Bankhead Coley Research Program to test whether an intervention with components aimed at the system, clinician and patient levels successfully promotes both hepatitis C virus screening and colorectal cancer screening among patients ages 45 to 75. This newly funded study will be conducted in partnership with Health Choice Network and at a Florida community health center.

Headshot of Dr. Clement Gwede

Clement Gwede, PhD

“By pairing these two cancer screenings, we seek to address system-level and practical barriers such as time by addressing both screening tests during a single clinic visit,” Christy said. “The intervention will include patient education about both screening tests, access to free colorectal cancer screening and hepatitis C virus screening, education for providers and will leverage the electronic health record, among others. Our hope is that this intervention will successfully address some of the common barriers to completing screening, such as lack of provider recommendation, information needs and access.”

"If found to be successful, effective bundling of multiple cancer screening tests would help us move beyond our current approach of offering ‘one-test-at-time’ over multiple visits. This is especially important for screening tests that must be done annually or at frequent intervals. A ‘one-stop’ approach is also crucial to reduce burden on patients,” Gwede said.

What You Need to Know

  • Get Screened: If you are between 45 and 75, ensure you get screened for colorectal cancer at ongoing intervals. If you are 18 or older, get screened for the Hepatitis C virus at least once before age 79.
  • Talk to Your Doctor: Discuss the benefits of both these screening tests with your health care provider. They can give you with the necessary information and referrals.
  • Stay Informed: Awareness is the first step toward prevention. Stay informed about the latest screening guidelines and recommendations.
  • Overcome Barriers: If you lack insurance or face other barriers to completing screening, seek out community health centers and patient assistance programs that offer free or low-cost screenings.