Weekly Virtual Symptom Check-Ins Linked to Better Quality of Life in Advanced Cancer

People with advanced cancer often deal with pain, fatigue, trouble sleeping and other symptoms that can change quickly. A new study presented at the American Society of Clinical Oncology Annual Meeting suggests that a simple mobile app may help patients manage those symptoms earlier and maintain their quality of life longer. 

The study tested a tool called SUPPORT+, which sends a weekly reminder asking patients or caregivers to answer a short questionnaire about physical and emotional symptoms. The app then provides practical steps for managing mild or moderate issues. If symptoms are severe or worsening, the app alerts a palliative care nurse, who follows up via the app or by phone. 

How The Study Worked 

More than 1,200 people with advanced cancer in Hong Kong took part in the randomized trial. All were receiving palliative care and were no longer on active cancer treatment. Half used the SUPPORT+ app for 18 weeks. The other half received usual care, which included clinic visits every few weeks and calling their care team if symptoms worsened. 

Researchers found that people using the app maintained their quality of life better than those receiving usual care. While some decline was expected as their cancers progressed, the drop was smaller for the app users. They also had fewer hospital admissions and shorter hospital stays. 

Tim Hembree, DO, PhD

Tim Hembree, DO, PhD, chief quality officer at Moffitt Cancer Center, says the findings reflect a broader shift in cancer care. “Proactive symptom monitoring gives patients a chance to get help before symptoms spiral,” he said. “This study shows that a simple weekly check‑in can make a real difference in how people feel and how often they need emergency care.” 

The study also highlighted the importance of caregiver involvement. Nearly 70% of SUPPORT+ users relied on a caregiver to help complete the weekly questionnaire. 

Hembree notes that digital tools only work when patients or caregivers can use them comfortably. “Technology can extend care beyond the clinic, but it has to be easy to use,” he said. “The real value comes when these tools are tied to a responsive care team that can act quickly.” 

Next Steps 

Researchers plan to continue developing the SUPPORT+ platform, including exploring AI‑supported features that could offer more timely guidance. They also plan to study cost effectiveness and long‑term sustainability. 

For patients and families, the takeaway is simple: Regular symptom check‑ins, even through a smartphone, may help people with advanced cancer stay more comfortable at home and avoid unnecessary hospital visits.