Sarah Tepper, MD

Cancer Focus:
Sarcoma

Dr. Tepper earned her medical degree from Washington University School of Medicine in St. Louis, Missouri, and she completed her Orthopaedic Surgery Residency at Rush University Medical Center in Chicago, Illinois. Most recently, she completed a Musculoskeletal Oncology Fellowship at Moffitt Cancer Center.

Dr. Tepper’s clinical interests include the treatment of bone and soft tissue sarcomas, benign tumors, and metastatic bone disease, with a particular focus on foot and ankle tumors. Her research is centered on advancing reconstruction techniques following tumor resection in the lower extremity and leveraging innovative technology to improve outcomes in Orthopedic Oncology. We are excited to have Dr. Tepper join our team and look forward to the expertise and innovation she brings to our mission. 

• Jeys LM, Botello E, Boyle R, Ebeid W, Hilton T, Houdek MT, Hosking K, Kurisunkal VJ, Laubscher M, Morris GV, Puri A, Ruggieri P, Laitinen MK, Abdul Bari Y, Abood A, Abraham JA, Acosta Marin M, Agarwal M, Agarwal R, Aguirre M, Ajit Singh V, Akiyama T, Al Farii H, Alaqeel M, Alaseem A, Aldosari O, Alexander K, Alfaro P, Aljuhani W, Allison DC, Almashahedi M, Alotaibi A, Alpan B, Alshaygy IS, Althunayan T, Andreani L, Andreou D, Andriandi A, Annabelle L, Aponte-Tinao L, Ardelt M, Armas S, Aston W, Aycan OE, Baad-Hansen T, Baeza P, Baird C, Balach T, Banse X, Barriga J, Barry J, Basile G, Bastoni S, Basuki MH, Bauer HC, Baydar S, Bayliss L, Becker R, Bedi A, Benevenia J, Bengoa F, Berger C, Bernthal N, Binitie O, Bird J, Bobseit A, Bodian C, Boffano M, Bonilla Huertas P, Bramer J, Broadhead M, Broekhuis D, Broida SE, Brown D, Bruschi A, Budny T, Buist M, Burke Z, Busse T, Cabrolier J, Calvo-Haro JA, Campanacci DA, Cardoso R, Carey Smith R, Carrasco MG, Casales N, Castan A, Ceballos O, Chan CM, Chan L, Chang LZ, Charoenlap C, Chaustre Florez JF, Chin J, Choong P, Chrobok A, Chung YG, Ciechanowicz D, Clara-Altamirano MA, Consuegra Guzman LA, Cornu O, Coubeau L, Courtot L, Crawford B, Cribb G, Cuervo-Lozano CE, Dammerer D, de la Rosa P, de Lima Corvino D, De Paolis M, De Santos de la Fuente FJ, de Vaal M, Deisenhofer JM, Delgado Obando J, Demir E, Deo S, Deventer N, Di Bella C, Dierselhuis E, Docquier PL, Domson G, Donati DM, Doshi A, Duivenvoorden MJC, Duran-Ciarrochi R, Dürr ...
• Smolle MA, Wenzl FA, Laitinen MK, Jeys LM, Leithner A, Abdul Bari Y, Abood A, Abraham J, Acosta M, Agarwal R, Agarwal M, Ajit Singh V, Akiyama T, Al Farii H, Aldosari Omar A, Alfaro P, Aljuhani W, Allison D, Almashahedi M, Alotaibi A, Alpan B, Alshaygy Ibrahim S, Althunayan T, Andreani L, Andreou D, Andriandi A, Annabell L, Aponte-Tinao L, Armas S, Aston W, Aycan Osman E, Baad-Hansen T, Baird C, Balach T, Barriga Juan A, Barry J, Basile G, Bastoni S, Basuki Mohammad H, Bauer H, Bayliss L, Becker R, Bedi A, Benevenia J, Bengoa F, Berger C, Bernthal N, Binitie O, Bird JE, Bobseit A, Bodian C, Boffano M, Bonilla Huertas P, Botello E, Boyle R, Bramer J, Broekhuis D, Broida SE, Brown D, Budny T, Burke Z, Cabrolier J, Calvo Haro Jose A, Campanacci DA, Cardoso R, Carey Smith R, Casales Fresenga N, Ceballos O, Chan Chung M, Chan L, Choong P, Chrobok A, Chung YG, Ciechanowicz D, Clara-Altamirano Miguel A, Consuegra L, Courtot L, Crawford B, Cribb G, Cuervo-Lozano Carlos E, Dammerer D, de la Rosa P, De Paolis M, De Santos de la Fuente Francisco J, de Vaal M, Deisenhofer J, Delgado J, Deo S, Deventer N, Di Bella C, Dierselhuis E, Domson G, Donati DM, Duran-Ciarrochi R, Durr Hans R, Ebeid W, Ehlers P, El Ghoneimy Ahmed M, El Motassime A, Eloi Pinto Fabio F, Endo M, Epstein G, Eralp L, Etaiwi M, Eward W, Fabbri N, Faimali M, Farooq A, Farooque K, Ferguson P, Ferreira N, Fiorenza F, Fonseca de Freitas J, Forsberg Jonathan A, Fuchs B, Fujiwara T, Funovics Philipp T, Fuzy E, Galli Serra ...
• Cummings C, Redding J, Chose C, Tepper SC, Joyce DM, Binitie OT, Caracciolo JT, Lazarides AL. Bone marrow edema as an independent imaging predictor of dedifferentiated chondrosarcoma. J Orthop Surg Res. 2026 Jul. Pubmedid: 42458556.
• Karadimas TL, Kucharik MP, Tepper SC, Joyce DM, Letson GD, Binitie OT, Chebli CM, Lazarides AL. A comparison of hemiarthroplasty with aortograft vs. reverse total shoulder arthroplasty following proximal humeral oncologic resection. J Shoulder Elbow Surg. 2026 Jul.35(7):1677-1684. Pubmedid: 41672300.
• Vucicevic RS, Castonguay JB, Treviño N, Munim M, Tepper SC, Haydon R, Peabody TD, Blank A, Colman MW. Surgeon perspectives on a virtual reality platform for preoperative planning in complex bone sarcomas. J Orthop. 2025 Apr.62:43-48. Pubmedid: 39507951. Pmcid: PMC11535880.
• Tepper SC, Lee L, Fice MP, Jones CM, Buac N, Vijayakumar G, Wang D, Colman MW, Gitelis S, Blank AT. Radiotherapy leads to improved overall survival in patients undergoing resection for Undifferentiated pleomorphic sarcoma. Surg Oncol. 2024 Oct.56:102118. Pubmedid: 39121675.
• Tepper SC, Lee L, Kasson LB, Herbst LR, Vijayakumar G, Colman MW, Gitelis S, Blank AT. Hip Arthroplasty Outcomes in Patients with Metastatic Bone Disease. Orthop Rev (Pavia). 2024 Mar.16:94568. Pubmedid: 38505134. Pmcid: PMC10950198.
• Yu A, Lee L, Yi T, Fice M, Achar RK, Tepper S, Jones C, Klein E, Buac N, Lopez-Hisijos N, Colman MW, Gitelis S, Blank AT. Development and external validation of a machine learning model for prediction of survival in extremity leiomyosarcoma. Surg Oncol. 2024 Dec.57:102057. Pubmedid: 38462387.
• Dhillon N, Vijayakumar G, Tepper SC, Braun A, Blank AT. A Rare Location of Osteosarcoma in the Cuboid Bone: A Case Report. JBJS Case Connect. 2023 Jul.13(3). Pubmedid: 37535761.
• Tepper SC, Lee L, Fice MP, Jones CM, Klein ED, Vijayakumar G, Batus M, Colman MW, Gitelis S, Blank AT. Association between neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, and survival in undifferentiated pleomorphic sarcoma (NLR, PLR, and overall survival in UPS). Surg Oncol. 2023 Aug.49:101949. Pubmedid: 37263041.
• Go R, Lee L, Vijayakumar G, Tepper S, Gitelis S, Blank A. Epithelioid hemangioendothelioma of the distal lower extremity and the role of radiotherapy: A report of two cases. Rare Tumors. 2023 Apr.15. Pubmedid: 37124838. Pmcid: PMC10134116.
• Lee LH, Tepper S, Owen G, Wang D, Lopez-Hisijos N, Colman MW, Gitelis S, Blank AT. Radiotherapy, volume reduction, and short-term surgical outcomes in the treatment of large myxoid liposarcomas. Radiat Oncol J. 2022 Sep.40(3):172-179. Pubmedid: 36065469. Pmcid: PMC9535413.
• Waldvogel NJ, Tepper SC, Lee L, Gusho C, Miller I, White GM, Ralls ML, Wang D, Gitelis S, Blank AT. Neoadjuvant radiation influences the pseudocapsule in soft tissue sarcoma: A histopathologic and radiographic evaluation. Surg Oncol. 2022 Sep.44:101828. Pubmedid: 36150270.
• Tepper SC, Spellman AM, Gusho CA, Blank AT. En Bloc Resection of Giant Cell Tumor following Neoadjuvant Denosumab: A Case Report and Review of the Literature. Orthop Rev (Pavia). 2022 May.14(4):35457. Pubmedid: 35769649. Pmcid: PMC9235432.
• Tepper SC, Holten AK, Jeffe DB, England PH, Hong ZL, Pérez M, Ghert M, Hirbe AC, Cipriano CA. Examining patient perspectives on sarcoma surveillance: The Sarcoma Surveillance Survey. Surg Oncol. 2022 Dec.45:101861. Pubmedid: 36270157. Pmcid: PMC9729379.
• DeFroda S, Fice M, Tepper S, Bach BR. Our Preferred Technique for Bone-Patellar Tendon-Bone Allograft Preparation. Arthrosc Tech. 2021 Nov.10(11):e2591-e2596. Pubmedid: 34868866. Pmcid: PMC8626798.
• Gusho CA, Tepper SC, Gitelis S, Blank AT. Epithelioid hemangioendothelioma of bone: A survival analysis of 50 cases from the SEER database (1992-2016). Rare Tumors. 2021 Apr.13. Pubmedid: 33953894. Pmcid: PMC8044559.
• Tepper SC, Gottlich CP, Nasr IW, Sponseller PD. Brachial Artery Pseudoaneurysm After Supracondylar Humerus Fracture: A Case Report. JBJS Case Connect. 2020 Jan.10(1):e0218. Pubmedid: 32224644.
• Tepper SC, Blank AT, Gitelis S, Colman MW. Pelvic ring reconstruction with segmental spinal instrumentation after complete type I pelvic resection. J Surg Oncol. 2020 Dec.122(8):1721-1730. Pubmedid: 32844400.
• Tepper S, Garcia MB, Fischer I, Ahmed A, Khan A, Balsara KR, Masood MF, Itoh A. Clinical Outcomes and Reduced Pulmonary Artery Pressure With Intra-Aortic Balloon Pump During Central Extracorporeal Life Support. Asaio J. 2019 Feb.65(2):173-179. Pubmedid: 29613887.
• Tepper S, Itoh A. Reply. Ann Thorac Surg. 2018 Jun.105(6):1861-1862. Pubmedid: 29253464.
• Tepper S, Itoh A. Reply. Ann Thorac Surg. 2018 Jun.105(6):1858-1859. Pubmedid: 29253462.
• Tepper S, Masood MF, Baltazar Garcia M, Pisani M, Ewald GA, Lasala JM, Bach RG, Singh J, Balsara KR, Itoh A. Left Ventricular Unloading by Impella Device Versus Surgical Vent During Extracorporeal Life Support. Ann Thorac Surg. 2017 Sep.104(3):861-867. Pubmedid: 28347536.
• Avey D, Tepper S, Pifer B, Bahga A, Williams H, Gillen J, Li W, Ogden S, Zhu F. Discovery of a Coregulatory Interaction between Kaposi's Sarcoma-Associated Herpesvirus ORF45 and the Viral Protein Kinase ORF36. J Virol. 2016 Jul.90(13):5953-5964. Pubmedid: 27099309. Pmcid: PMC4907238.
• Avey D, Tepper S, Li W, Turpin Z, Zhu F. Phosphoproteomic Analysis of KSHV-Infected Cells Reveals Roles of ORF45-Activated RSK during Lytic Replication. PLoS Pathog. 2015 Jul.11(7):e1004993. Pubmedid: 26133373. Pmcid: PMC4489790.