Department Metrics

• (00014262) Mechanisms of Radioresistance and Strategies for Radiosensitization in Ovarian Clear Cell Carcinoma
  Award Number:
  Sponsor: Nat Institutes of Health
  PI:Mo, Q.
• Overcoming Metastatic Spread of Osteosarcoma with RNA Loaded Nanoparticles
  Award Number:
  Sponsor: Nat Institutes of Health
  PI:Yin, V.
• Deconvolute Key Biological Drivers That Define Subsets of Lethal Prostate Cancer in African American Men
  Award Number:
  Sponsor: US Army
  PI:Berglund, A.
• Epstein-Barr Virus Driven Tonsillar Versus Peripheral B-cell One-Carbon Metabolic Network Remodeling
  Award Number:
  Sponsor: Nat Institutes of Health
  PI:Teng, M.
• Dissecting Enhancer Function Through Integrative Genomics
  Award Number:
  Sponsor: Nat Institutes of Health
  PI:Teng, M.
• Metabolic and Molecular Regulation of Myeloid Cell Functions in Brain Cancer
  Award Number:
  Sponsor: Nat Institutes of Health
  PI:Yu, X.
• Developing a Cancer Galaxy Computational Workbench to Meet Emerging Cancer Data Analysis Needs
  Award Number:
  Sponsor: Nat Institutes of Health
  PI:Goecks, J.

CLINICAL TRIAL 23782
Development of Novel Predictive Biomarkers to Enhance Utility of Cetuximab Therapy for Colorectal Cancer
Condition: Gastrointestinal Tumor
Intervention:

• Tarhini AA, Khaksar MA, Chen Z, Lee SJ, Hodi FS, Li T, Yoder SJ, Streicher H, Hwu P, Sondak VK, Kirkwood JM, Wang X, Kanetsky PA. Evidence of genetic susceptibility to immune-related dermatitis in patients with melanoma treated with immune checkpoint inhibitors. Melanoma Res. 2026 Oct.36(5):407-415. Pubmedid: 42647409.
• Kostrykin L, Massei R, Chiang D, Wollmann T, Burel JM, Tabernero DL, Sun Y, Gao Q, Paul MW, Videm P, Watson C, Franco-Barranco D, Kumar A, Goué N, Koopaei RT, Ulman V, Jum'ah K, Poterlowicz K, Etzrodt M, Muñoz-Barrutia A, Le Dévédec SE, Moore J, Goecks J, Gruening B, Rohr K, Serrano-Solano B. Bioimage management and analysis in Galaxy: Tools, workflows, training, and community practices. J Microsc. 2026 Sep. Pubmedid: 42709042.
• Hatoum F, Dyer B, Heiligh J, Poehlman T, Zhang J, Jameel G, Mizelle S, Patel A, Schneider A, Fazili A, Johnson JS, Miller JW, Roman Souza G, Mahmoud N, Gullapalli K, Kim Y, Spiess PE, Gatenby R, Anderson ARA, Chahoud J. A phase II study assessing the feasibility and clinical efficacy of adaptive immunotherapy combination with VEGFR-TKI in patients with advanced renal cell carcinoma. Future Oncol. 2026 Sep.1-9. Pubmedid: 42719952.
• Richards AR, Gomez MF, Dowling BI, Bulka CM, Gigic B, Figueiredo JC, Li CI, Shibata D, Toriola AT, Byrd DA, Ulrich CM, Teng M, Stewart PA, Siegel EM, Kresovich JK. Abundance and balance of circulating leukocyte subsets and colorectal cancer survival. Brit J Cancer. 2026 Sep.135(5):756-762. Pubmedid: 42237020. Pmcid: PMC13478470.
• Noble JD, Peixoto BC, Menges MA, Abraham-Miranda J, Savid-Frontera C, Sawyer W, Sorathia VD, Cuadrado Delgado LA, Corallo SA, Llanos JC, Merritt EC, De Avila G, Castaneda-Puglianini OA, Liu HD, Alsina M, Nishihori T, Shain KH, Siqueira Silva AS, Baz RC, Blue BJ, Grajales-Cruz AF, Hansen DK, Cleveland JL, Perna F, Lynch CC, Binning JM, Atkins RM, Song X, Locke FL, Freeman CL. Product-intrinsic NF-κB-driven transcriptional programs connote durability of CAR-T response in multiple myeloma. Blood. 2026 Sep.148(11):1409-1422. Pubmedid: 42275255.
• Deng R, De Oliveira Silva T, Liu X, Fan C, Young Seok H, Wu J, Wickramage I, Guo H, Lin T, Zhang S, Semerci N, Taheri S, Lu YW, Huang ZP, Mably JD, Teng M, Chen H, Diniz GP, Wang DZ. Treatment with the Nox1/4 inhibitor Setanaxib ameliorates cardiac function in mouse models of Duchenne muscular dystrophy. Mol Ther. 2026 Sep.34(9):5593-5606. Pubmedid: 42363603. Pmcid: PMC13453391.
• Avasthi KK, Yim KH, Kim Y, Echevarria PMR, Darst LM, Abreu N, Zea KP, Hayes MT, Vosoughi A, Manley BJ, Wang L. Multiplex RT-PCR-Based Sequencing Assay to Detect Kidney Cancer-Specific Splice Variants in Tumor Tissues and Plasma Cell-Free RNAs. Mol Diagn Ther. 2026 Sep.30(5):821-832. Pubmedid: 42410176.
• Kasting ML, Sutton SK, Davish M, Quinn GP, Donahue KL, Christy SM. Clinicians' self-reported HPV vaccination recommendations for sexual and gender minority patients. Vaccine. 2026 Sep.90:129037. Pubmedid: 42600245. Pmcid: PMC13543079.
• Saeed H, Varela MM, Sahakian E, Naqvi M, Mo Q, Zhang L, Makanji R, Zhang Y, Dong N, Isenalumhe L, Gaballa S, Chavez J, Shah B, Bello C, Sokol L, Pinilla-Ibarz J. A Phase 1 Trial of Duvelisib and Oral Azacitidine in Relapsed/Refractory T-Cell Lymphoma. Hematol Oncol. 2026 Sep.44(5):e70235. Pubmedid: 42545812. Pmcid: PMC13431344.
• Sutton SK, Turner K, Chung-Bridges K, Vadaparampil ST, Abdulla R, Arevalo M, Avrilien N, Byrne MM, Endemano E, Hernandez JG, Hamilton JG, Lyjak E, Parrales Z, Ramos J, Torres M, White B, Hay JL, Kanetsky PA. A hybrid effectiveness-implementation trial to integrate precision skin cancer risk feedback in federally qualified health centers. Contemp Clin Trials. 2026 Aug.169:108439. Pubmedid: 42600921. Pmcid: PMC13527874.
• Ran Y, Zhang K, Shen YT, Mo Q, Wang Z, Yalamanchili HK, John S, Kogiso M, Gao X, Wang C, Sinha T, Black BL, Chen MH. Lineage tracing reveals a shared cellular origin for supraclavicular brown and inguinal beige adipocytes. Cell Rep. 2026 Aug.45(8):117836. Pubmedid: 42599804.
• Silvane L, Zelenka T, Talada DP, Cismasiu VB, Islam S, Singh RP, Ngove Z, Chakraborty S, Hall MS, Blauvelt JL, Eksioglu E, Manrique SZ, Johnson JO, Obermayer AN, Alfaro A, Huang W, Sarnaik A, Tarhini AA, Mullinax JE, George E, Hwu P, Davila E, Conejo-Garcia JR, Bryceson YT, Chen DT, Shaw TI, Pilon-Thomas S, Avram D. BCL11B targeting in tumor CD8 + T cells amplifies anti-tumor response by blocking exhaustion while promoting stemness and cytotoxicity. bioRxiv. 2026 Aug. Pubmedid: 42601873. Pmcid: PMC13470569.
• Yin J, Francis KE, Lopes GS, So J, Olswold CL, Van Cutsem E, Bokemeyer C, Adams R, Chibaudel B, Grothey A, Yoshino T, De Gramont A, Shi Q, Tournigand C, Sjoquist KM, Zalcberg J. Evaluating longitudinal toxicity and adverse event in cetuximab-treated metastatic colorectal cancer: a pooled analysis from 1,302 patients in ARCAD database. J Natl Cancer Inst. 2026 Aug. Pubmedid: 42636265.
• Martinez-Planes E, Ramello MC, Fontela MG, Shokri MR, Tran T, Darville L, Koomen J, Kim Y, Abate-Daga D. C-terminal CD28 phosphorylation, pY218, modulates IL-2 secretion and therapeutic effect of CAR-T cells. Mol Ther. 2026 Aug. Pubmedid: 42642932.
• Kumar NB, Schabath M, Alexandrow M, Gray J, Tanvetyanon T, Khalil F, Laborde J, Schell MJ, Klippenstein D. Multidimensional LDCT Imaging Endpoints for a Randomized Pilot Phase II Trial of Curcumin and Omega-3 Fatty Acids for Lung Cancer Chemoprevention: Results of a Randomized Pilot Trial. Cancers (Basel). 2026 Aug.18(16). Pubmedid: 42649879. Pmcid: PMC13510763.
• Le THN, Nguyen QT, Kim Y, Balkaran V, Bhathivi T, Pilon-Thomas S, Markowitz J. pAc/Emm55 increases anti-melanoma immunity via TLR2 signaling in dendritic cells and improves checkpoint blockade efficacy. Front Immunol. 2026 Aug.17:1863894. Pubmedid: 42688222. Pmcid: PMC13534055.
• Xu X, Liu X, Jarajapu V, Neelature Sriramareddy S, Konecny F, Posorske B, Dollar JJ, Liu X, Jasani N, Wang K, Mecozzi N, Soto-Vargas Z, Ochoa-Rios SL, Murikipudi H, Phan N, Chadourne M, Kuznetsoff JN, Sinard J, Bennett RL, Licht JD, Smalley KSM, Harbour JW, Yu X, Karreth FA. A Multistep Immune-Competent Genetically Engineered Mouse Model Reveals Phenotypic Plasticity in Uveal Melanoma. Cancer Res. 2026 Aug.86(15):3666-3686. Pubmedid: 41661679. Pmcid: PMC12974268.
• Mandal G, Biswas S, Anadon CM, Tamuli B, Chaurio RA, Lopez-Bailon LU, Plappert N, Carrion-Estrada D, Mine JA, Lai CH, Moreno AP, Johnson J, Moran-Segura CM, Fang B, Marchion D, Chaudhary N, Terry KL, Sasamoto N, Townsend MK, O'Brien J, Antonia SJ, Tworoger SS, Yu X, Rodriguez PC, Conejo-Garcia JR. Isotype-switched antibodies originating from tertiary lymphoid structures can antagonize ovarian cancer progression. iScience. 2026 Aug.29(8):116757. Pubmedid: 42472098. Pmcid: PMC13380442.
• Karapetyan L, Xu J, Ward K, Kalos D, Schachner B, Ali J, Song X, Kuriakose J, Hall MS, Chau J, Cox CA, Al-Bzour AN, Falahat R, Perez MC, Mullinax JE, Zager JS, Gonzalez R, Sondak VK, Tsai KY, Messina JL, Moran-Segura C, Lopez-Blanco N, Alleyne AE, Nguyen JV, Schell MJ, Markowitz J, Brohl AS, Eroglu Z, Tarhini AA, Khushalani NI, Hwu P, Mulé JJ, Sarnaik AA, Beatty MS, Pilon-Thomas S. Immunologic determinants of infusion products and the tumor microenvironment govern response to TIL therapy in advanced melanoma. Med (N Y). 2026 Aug.7(8):101231. Pubmedid: 42526429. Pmcid: PMC13425943.
• Fennell BS, Hoogland CE, Cottrell-Daniels C, Bui TC, Sutton SK, Shahani L, Businelle MS, Shih YT, Shukla PP, Vidrine JI, Vidrine DJ. Beyond Cigarettes: Cannabis Co-Use, ART Adherence, and Psychosocial Burden Among People With HIV Enrolled in a Smoking Cessation Randomized Controlled Trial. J Stud Alcohol Drugs. 2026 Jul. Pubmedid: 42397749.
• Mahmoud N, Mustasam A, Miller J, Lakhram A, Hatoum F, Thompson ZJ, Kim Y, Souza GR, Johnson JS, Safa H, Spiess PE, Chahoud J. Prognostic Role of PD-L1 in Penile Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis. J Natl Compr Canc Ne. 2026 Jul.24(8). Pubmedid: 42425150.
• Vincelette ND, Mo Q, Cheng CH, Park J, Kuykendall AT, Zhang L, Moon J, Razabdouski TN, Eksioglu EA, Lledo FM, Papenhausen PR, Xie Z, Chan O, Sallman DA, Pinilla-Ibarz J, Murphy DJ, Komrokji RS, Cleveland JL, Yu X, Yun S. Hematopoietic mosaic chromosomal alterations are pleiotropic drivers of inflammaging, multimorbidity, and mortality. medRxiv. 2026 Jul. Pubmedid: 42428085. Pmcid: PMC13345432.
• Saha A, Whiting J, Mohty R, Flores K, Kim J, Nishihori T, Chavez J, Gaballa S, Khimani F, Liu H, Shah B, Dam M, Jaffer M, Mokhtari S, Ghalehsari N, Elmariah H, Bachmeier C, Guevara JA, Jim H, Mirza S, Segal BH, Hansen DK, Bejanyan N, Perna F, Faramand R, Jain M, Locke F, Lazaryan A. A novel severe toxicity-free, and progression-free survival endpoint predicts outcomes after CD19 chimeric antigen receptor-T cell therapy in large B-cell lymphoma. Bone Marrow Transplant. 2026 Jul. Pubmedid: 42469394.
• Buro AW, Gomez MF, Kim Y, Ward NP, Umbarger M, Ma L, Vala A, Hogue S, Silva WV, Bailey A, Pierce CM, Kim Y, DeNicola GM, Byrd DA, Robinson LA. Metagenomic and Metabolomic Correlates of Immunotherapy Response in Non-Small Cell Lung Cancer. Res Sq. 2026 Jul. Pubmedid: 42466390. Pmcid: PMC13370620.
• Pidala JA, Kim J, Laborde J, Knott S, Mogili K, Zinn J, Monroe AR, Faramand R, Ramlal R, Khimani F, Hansen DK, Torres Luna NE, Jain MD, Perez LE, Mishra A, Ghalehsari N, Castaneda-Puglianini OA, Alsina M, Perna F, Nieder M, Mirza AS, Liu HD, Nishihori T, Ali A, Chellapandian D, Locke FL, Bejanyan N, Anasetti C, Lazaryan A. Chronic graft vs. host disease following post-transplant cyclophosphamide (PTCy) based prophylaxis vs. non-PTCy prophylaxis. Blood Adv. 2026 Jul. Pubmedid: 42480215.
• Davis EW, Park MA, Basinski TL, Alhassan S, Gomez MF, Genilo-Delgado M, Sinnamon AJ, Hodul PJ, Karolak A, Sayegh Z, Nguyen J, Rummens B, Li J, Tripathi A, Parker NH, Pimiento JM, Rasool G, Tassielli AF, Chen DT, Centeno BA, Jiang K, Jeong D, Permuth JB. CT-Derived Radiomic Signature of MUC6 Expression Improves Guideline-Based Risk Stratification in Intraductal Papillary Mucinous Neoplasms. Cancers (Basel). 2026 Jul.18(14). Pubmedid: 42512328. Pmcid: PMC13406335.
• Sakitis CJ, Liao D, Reid BM, Townsend MK, Schildkraut JM, Lawson AB, Tworoger SS, Terry KL, Peres LC, Wrobel J, Soupir AC, Fridley BL. Functional Data Analysis of Spatial Clustering Identifies Prognostic T Cell Patterns in Ovarian Cancer. bioRxiv. 2026 Jul. Pubmedid: 42539217. Pmcid: PMC13419803.
• Caudell J, Echevarria M, Yang G, Kim Y, Kirtane K, Kish J, Muzaffar J, Zahid M, Chung C, Enderling H. Phase 2 Prospective Trial of Personalized Radiation Therapy Fractionation in Human Papillomavirus Positive Oropharyngeal Cancer. Int J Radiat Oncol Biol Phys. 2026 Jul.125(4):1043-1050. Pubmedid: 41519405. Pmcid: PMC13131356.
• Bandaru R, Fu H, Zheng H, Liang J, Wang L, Gulati S, Hinrichs BH, Teng M, Zhang B, Kocherginsky M, Lin DC, Hildeman DA, Worden FP, Old MO, Dunlap NE, Kaczmar JM, Gillison ML, El-Gamal D, Wise Draper T, Liu Y. Genome-wide variation in cell-free DNA end-motif entropy predicts immunotherapy response in head and neck cancer. J Clin Invest. 2026 Jul.136(13). Pubmedid: 42154530. Pmcid: PMC13322381.
• Arabzadeh M, Tang YH, Colin-Leitzinger C, Marzban S, Walgenbach D, Morganti S, Mahaganapathy V, Harper E, Teng M, Kresovich JK, Washington I, Parsons HA, Garber JE, West J, Ganesan S, Khiabanian H, Gillis N. Evolution of clonal hematopoiesis during cancer treatment and its impact on outcomes. J Clin Invest. 2026 Jul.136(14). Pubmedid: 42262879. Pmcid: PMC13367969.
• Brown NI, Rodrigues APS, Sutton SK, Stern M, Vadaparampil ST, Kanetsky PA. Differences in skin cancer-related beliefs and psychological distress among adults living in Florida who do and do not report a sunburn. Prev Med Rep. 2026 Jul.67:103534. Pubmedid: 42317408. Pmcid: PMC13273511.
• Nguyen QT, Kim Y, Le THN, Garg S, Balkaran V, Bhathivi T, Chamizo A, Dukes CW, Ward K, Brohl AS, Karapetyan L, Khushalani NI, Eroglu Z, Tarhini AA, Mulé JJ, Markowitz J. iNOS is a key mediator of anti-PD-1 melanoma therapy response. Front Immunol. 2026 Jun.17:1837275. Pubmedid: 42440610. Pmcid: PMC13333588.
• Canevarolo RR, Sudalagunta PR, Meads MB, Silva M, Zhao X, Magaletti D, Alugubelli RR, DeAvila G, DeAvila D, Persi E, Maura F, Bell ET, Bishop RT, Cubitt CL, Sansil SS, Zhang W, Teer JK, Teng M, Yoder SJ, Siegel EM, Shah BD, Nishihori T, Hazlehurst L, Lynch CC, Landgren O, Hampton O, Gatenby RA, Sullivan DM, Brayer J, Dalton W, Cleveland JL, Alsina M, Baz R, Shain KH, Silva AS. Integrated Genomic and Epigenomic Analysis Reveals Epigenetic Plasticity in Disease Progression and Multidrug Resistance in Multiple Myeloma. Cancer Res. 2026 Jun. Pubmedid: 42233980.
• Hoogland CE, Sutton SK, Jones SR, Nagy B, Brockway SJ, Himmelgreen D, Mantz T, Businelle MS, Shih YT, Vidrine JI, Vidrine DJ. Sociodemographic Paradoxes and Enrollment Differences in In-Person Versus Online Recruitment to a Mobile Health Smoking Cessation Intervention for Food-Insecure Adults: Secondary Analysis of a Randomized Controlled Trial. J Med Internet Res. 2026 Jun.28:e80530. Pubmedid: 42275630. Pmcid: PMC13258061.
• Tagal V, Li T, Kumar R, Shrestha P, Yu X, Miroshnychenko D, Olumoyin K, Marusyk A, Davies M, Maudsley S, El-Naqa I, Gomes AP, Duckett DR, Han HS, Andor N. Ploidy shapes gemcitabine response through altered potency and delayed cell death. bioRxiv. 2026 Jun. Pubmedid: 42282758. Pmcid: PMC13251900.
• Churchman M, Lu X, McKean D, Radmacher M, Zhang Q, Rounbehler R, Tan A, Shaw T, Obermayer A, Grass G, Spakowicz D, Tarhini A, Shain K, Canevarolo R, Meads M, Silva AS, Sudalagunta PR, Manley B, Huntsman S, Collyar D, Kolesar J, Evers BM, Single N, Edge S, Johnson C, Weiner G, McCarter M, Borges V, Horne L, Lillard J, Mudaranthakam D, White J, Libutti S, Ganesan S, Riedlinger G, Loughran T, Halme D, Johns M, Arciero C, Salhia B, Naqash AR, Shriver C, Lee K, Schneider B, Nix D, Fillmore G, Colman H, Ulrich C, Springer B, Pollock R, Vucic E, Sherman J, Jain A, Dalton W, Agius P, Siegel E. The Oncology Research Information Exchange Network (ORIEN) - Building a Real-World Collaborative, Patient-driven Infrastructure for Discovery Research and Precision Oncology. Res Sq. 2026 Jun. Pubmedid: 42281974. Pmcid: PMC13252564.
• Parker NH, Kim J, Bean M, De Vera MT, Carmella R, Duca A, Corallo S, Delgado LC, Merritt E, McCoy J, Brushwood A, Franca M, Hansen DK, Castaneda-Puglianini O, Lazaryan A, Chavez J, Nishihori T, Shah B, Faramand R, Mirza AS, Akhtar O, Peres LC, Figura NB, Jhaveri K, Oswald LB, Jim HSL, Locke FL, Jain M, Freeman CL. Exercise Prehabilitation for Older Adults Undergoing CAR-T: Feasibility, Acceptability, and Preliminary Outcomes. Transplant Cell Ther. 2026 Jun. Pubmedid: 42315024.
• Tarhini AA, Khaksar MA, Chen Z, Lee SJ, Stephen Hodi F, Li T, Yoder SJ, Streicher H, Sondak VK, Kirkwood JM, Wang X, Kanetsky PA. Predicting immune-related thyroiditis using polygenic risk scores in patients with advanced melanoma. J Immunother Cancer. 2026 Jun.14(6). Pubmedid: 42320988. Pmcid: PMC13289257.
• Pidala JA, Cieri N, Schell MJ, Song X, Shao Y, Cao B, Du D, Thapa R, Betts BC, Janssen W, Cubitt C, Yoder SJ, O'Leary MF, Beato F, Veerapathran A, Menges MA, Burton M, Bejanyan N, Castaneda-Puglianini OA, Elmariah H, Faramand RG, Fernandez HF, Hansen DK, Jain MD, Khimani F, Lazaryan A, Liu HD, Locke FL, Mirza AS, Mishra A, Nieder M, Nishihori T, Ochoa L, Perez LE, Perna F, Ramlal R, Torres NE, Anasetti C. Expanded antigen-specific donor regulatory T cells for GVHD prevention. Blood. 2026 Jun. Pubmedid: 42322116.
• Horta M, Poudel R, Brandon KO, Dougan SO, Yates H, Rivera MS, Martinez U, Sutton SK, Vidrine DJ, Ritterband LM, Wiseman KP, Vickerman KA, Turner K, Byrne MM, Yang MJ, Anyanwu OA, Brandon TH, Vinci C. Glitches to growth: Lessons learned from developing and testing an augmented reality smartphone app for substance use treatment. Exp Clin Psychopharmac. 2026 Jun.34(3):261-270. Pubmedid: 41411021. Pmcid: PMC12716370.
• Tarhini AA, Khaksar MA, Chen Z, Lee SJ, Hodi FS, Li T, Monteiro AN, Streicher H, Sondak VK, Wang X, Kirkwood JM, Kanetsky PA. Insights into inherited genetic variations and genetic ancestry of patients with high-risk melanoma. Melanoma Res. 2026 Jun.36(3):189-196. Pubmedid: 41812038. Pmcid: PMC13254891.
• Ramlal R, Kim J, Thompson Z, Ochoa-Bayona L, Mishra A, Nishihori T, Perez L, Bejanyan N, Castaneda Puglianini O, Faramand R, Mirza S, Khimani F, Lazaryan A, Hansen D, Locke F, Artz A, Sorror M, Pidala J. Single center evaluation of a composite risk assessment model to predict non-relapse mortality following allogeneic hematopoietic cell transplantation (HCT). Bone Marrow Transplant. 2026 Jun.61(6):702-704. Pubmedid: 41951840.
• Beltrame A, Villa LL, Lazcano-Ponce E, Carvalho da Silva R, Galan de Paula L, Fan W, Sirak B, Dukes CW, Rathwell J, Isaacs-Soriano K, Schell MJ, Giuliano AR. Association of alcohol consumption with oral high-risk human papillomavirus infection: a cross-sectional study within the multinational HPV infection in men (HIM) cohort. Lancet Reg Health Am. 2026 Jun.58:101464. Pubmedid: 42005087. Pmcid: PMC13085074.
• Alger E, Mandrekar SJ, Yin J, Yap C. PRO-ADD: Patient-empowered dose-finding trials integrating safety, preliminary efficacy and patient-reported outcomes for optimal dose selection. Stat Methods Med Res. 2026 Jun.35(6):1177-1198. Pubmedid: 42057418. Pmcid: PMC13283501.
• Beltrame A, Giuliano AR, Villa LL, Lazcano-Ponce E, Santana-Bagur J, Allen-Leigh B, Portillo-Romero AJ, Sahasrabuddhe VV, House MG, Brofsky E, de Paula LG, da Silva RC, Schell MJ, Rathwell J, Isaacs-Soriano K, Fan W, Mello C, Ellsworth GB, Wilkin T. Genotype distribution of human papillomavirus (HPV) types in oral gargle specimens among men living with HIV in Mexico, Brazil, and Puerto Rico: A cross-sectional study. J Infection. 2026 Jun.92(6):106751. Pubmedid: 42070588. Pmcid: PMC13362017.
• Onimus A, Celias D, Chang S, Davis J, Mandula J, Li J, Gardner A, Hänggi K, Osunmakinde O, Soliman H, Shaw TI, Rodriguez PC, Ruffell B. Taxane chemotherapy promotes response to TIM-3 checkpoint blockade via STING-mediated ER stress and HMGB1 secretion. Cell Rep Med. 2026 May.7(5):102788. Pubmedid: 42097146. Pmcid: PMC13198304.
• Sharma AB, Wang E, Selvakumar S, Koelmeyer H, Shetty S, Buckley K, Mo Q, Smith T, Chao A, Balen C, Mannam G, Yudiono J, Lien K, Khatib S, Paduchuri V, Al Ali N, Song J, Nishihori T, Lancet JE, Alomar M, Cleveland JL, Kuykendall A, Komrokji RS, Yun S, Lee DH. Real-world prevalence and outcome of elevated right ventricular systolic pressure in myelofibrosis. Cardiooncology. 2026 May.12(1). Pubmedid: 42106798. Pmcid: PMC13177858.
• Tanvetyanon T, Chen DT, Gray JE. HER-2 Altered Early-Stage Non-Small Cell Lung Cancer Had Better Survival than Triple-Negative Disease. J Clin Med. 2026 May.15(9). Pubmedid: 42123214. Pmcid: PMC13164032.
• Heine J, Fowler E, Eschrich S, Schell MJ. Synthetic Data Generation and Nonparametric Techniques for Assessing Multivariate Similarity to Address Small-Sample Size Challenges. bioRxiv. 2026 May. Pubmedid: 42146595. Pmcid: PMC13174472.
• Soupir AC, Townsend MK, Hathaway CA, Nguyen J, Moran Segura C, Saeed-Vafa D, Ospina OE, Peres LC, Conejo-Garcia JR, Terry KL, Tworoger SS, Fridley BL. Spatial Clustering of Recently Activated Cytotoxic Lymphocytes Improves Association with Overall Survival in Women with High-Grade Serous Ovarian Cancer. Cancer Epidemiol Biomarkers Prev. 2026 May.OF1-OF10. Pubmedid: 42159725.
• Vera O, Martinez M, Soto-Vargas Z, Wang K, Xu X, Mecozzi N, Murikipudi H, Ruiz-Buceta S, Chadourne M, Posorske B, Angarita A, Bok I, Ulloa Arrieta JD, Liu Q, Kim Y, Messina JL, Tsai KY, Major MB, Lau EK, Yu X, Ibanez de Caceres I, Karreth FA. A MAFG~MITF complex drives melanoma phenotype switching and progression. Nat Commun. 2026 May. Pubmedid: 42168173.
• Johnson JS, Miller JW, Hatoum F, Schell MJ, Yu X, Roman Souza G, Mizelle S, Gullapalli K, Fazili A, Jain R, Chatzkel J, Cen L, Dhillon J, Cubitt C, Yao J, Whiting J, Li J, Swank J, Jameel G, Zhang J, Wang X, Spiess PE, Fishman M, Chahoud J. Pembrolizumab plus high-dose IL-2 in advanced clear cell renal cell carcinoma: six-year survival outcomes and molecular signatures from a phase 2 trial. Nat Commun. 2026 May.17(1). Pubmedid: 42185255.
• Beltrame A, Villa LL, Lazcano-Ponce E, Santana-Bagur J, Allen-Leigh B, Portillo-Romero AJ, Sahasrabuddhe VV, House MG, Brofsky E, de Paula LG, da Silva RC, Fan W, Schell MJ, Rathwell J, Isaacs-Soriano K, Mello C, Ellsworth GB, Wilkin T, Giuliano AR. Alcohol consumption and oral human papillomavirus infection among men living with HIV: a cross-sectional study from the ULACNet 201 trial. Sci Rep. 2026 May. Pubmedid: 42215629.
• Sparrock LS, Vidrine JI, Vinci CE, El Naqa IM, Sutton SK, Salloum RG, Dallery J, Crane TE, Penedo FJ, Brockway SJ, Jones SR, Hoogland CE, Reich RR, Gonzalez-Calderon G, Simmons VN, Vidrine DJ. Creation of an mHealth Infrastructure to Support the Development and Delivery of mHealth Interventions: Protocol for Demonstration Projects Addressing Smoking Cessation in Cancer Care. JMIR Res Protoc. 2026 May.15:e92288. Pubmedid: 42214073. Pmcid: PMC13263659.
• Ahmed KA, Quick AM, Chon HS, Chern JY, Bixel K, Kim Y, Li J, Montejo ME, Dowell RA, Kim S, Fernandez DC, Lam CA, Hakam A, Rosa M, Shafique M, Shahzad MM, Wenham RM. Atezolizumab and Stereotactic Body Radiation in Metastatic, Recurrent, or Persistent Cervical Cancer: Results From a Phase 2 Multi-Institutional Study. Int J Radiat Oncol Biol Phys. 2026 May.125(1):298-305. Pubmedid: 40379142. Pmcid: PMC12699517.
• Christy SM, Sutton SK, Owens H, Trejos RF, Arevalo M, Meade CD, Lopez J, Sanders LJ, Vadaparampil ST, Park E, Ramos-Sepúlveda M, Borrego-Villanueva J, Patra C, Sanchez J, Marzán-Rodríguez M. Human papillomavirus vaccine knowledge, health beliefs, recommendation receipt, and intentions among Spanish-speaking Hispanic/Latino sexual and gender minority young adults assigned male at birth in Florida and Puerto Rico: results of a cross-sectional s. Ethn Health. 2026 May.31(4):263-281. Pubmedid: 41576421. Pmcid: PMC13048128.
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• Park R, Rind F, Kristoff T, Li J, Schell M, Slebos RJC, Thatikonda S, Chaudhary R, Biernacki MI, Meshkovska Y, Kaldas D, Kim HS, Farinhas J, Hernandez-Prera J, Kirtane K, Hall MS, Amelio AL, Rocco JW, Bhateja P, Steuer C, Bonomi M, Saba NF, Chung CH. Evaluation of Neutrophil to Lymphocyte Ratio in Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma Treated With a Combination of Cetuximab and Nivolumab in a Phase II Clinical Trial. Am J Clin Oncol. 2026 Apr.49(4):176-187. Pubmedid: 40905435. Pmcid: PMC13011960.
• Jazayeri B, Wang X, Li R. Re: Thomas Dreyer, Simone Brandt, Knud Fabrin, et al. Use of the Xpert Bladder Cancer Monitor Urinary Biomarker Test for Guiding Cystoscopy in High-grade Non-muscle-invasive Bladder Cancer: Results from the Randomized Controlled DaBlaCa-15 Trial. Eur Urol. Eur Urol. 2026 Apr.89(4):e95-e96. Pubmedid: 41107180.
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• Philbrook P, Dean MJ, Sanchez-Pino MD, Zheng LQ, Zabaleta J, Vázquez-Martínez JA, Chang D, Mandula JK, Shaw TI, Wyczechowska D, Garai J, Thylur Puttalingaiah R, Mansouri A, Huang W, Das S, Chang S, Conejo-Garcia JR, Rodriguez PC, Ochoa AC. Medium-Chain Fatty Acid Receptor GPR84 Modulates Cytotoxic CD8 T-cell Antitumor Immunity through Metabolic Reprogramming. Cancer Immunol Res. 2026 Apr.14(4):640-657. Pubmedid: 41557755. Pmcid: PMC12990994.
• Abdulla R, Boxtha C, Courtney EP, Anyanwu OA, Sutton SK, Chung-Bridges K, Kassaye HG, Philippe E, Mudon KA, Frias E, Parras D, Avrilien N, Friedman M, Turner K, Coronado GD, Champion VL, Tobin JN, Vadaparampil ST, Gwede CK, Christy SM. Multilevel Action Toward Colorectal Cancer and Hepatitis C Education and Screening (MATCHES): Study protocol for a hybrid 1 stepped-wedge multibehavioral randomized trial. Contemp Clin Trials. 2026 Apr.163:108256. Pubmedid: 41692274. Pmcid: PMC13094859.
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• Zhao D, Khatri VM, Nakashima JY, Chadha J, Chatwal M, Zhang J, Ionescu F, Linscott JA, Li R, Poch M, Sexton W, Yu A, Spiess PE, Zemp L, Gilbert SM, Manley B, Yin V, Jain R, Torres-Roca J, Johnstone P, Yamoah K, Grass GD. Early Detection of Metastatic Progression by Circulating Tumor DNA in Patients Undergoing Bladder-Preserving Trimodality Therapy. J Urol. 2026 Mar.215(3):305-315. Pubmedid: 41231842.
• Cao B, Yu X, Gonzalez G, Murthy AR, Li T, Shen Y, Yao S, Wang X. CGPA: A Multicontext Cancer Gene Prognosis Atlas. Mol Cancer Res. 2026 Mar.24(3):188-197. Pubmedid: 41528384. Pmcid: PMC12908732.
• Yang MJ, Sutton SK, Cottrell-Daniels C, Ritterband LM, Blackwell R, Maconi ML, Poudel R, Pabbathi S, Simmons VN, Vinci C. Mindfulness-based ecological momentary intervention for smoking cessation to address cancer-related relapse risk factors: Intervention development and usability findings. Mindfulness (N Y). 2026 Mar. Pubmedid: 41809575. Pmcid: PMC12971066.
• Liu X, Vidrine DJ, Sutton SK, Wetter DW, Jones SR, Vidrine JI, Shih YT. Cost-Effectiveness of Smoking Cessation Among Survivors of Cervical Intraepithelial Neoplasia or Cervical Cancer. JAMA Netw Open. 2026 Mar.9(3):e261543. Pubmedid: 41817524.
• Khaksar MA, Eljilany I, Yassine I, Yu X, Teer JK, Conejo-Garcia JR, Lyons M, LaFramboise W, Tarhini AA. Associations of Tumor Somatic Mutations and Genetic Alterations with Survival Outcomes in Melanoma Patients Treated with Ipilimumab. J Clin Med. 2026 Mar.15(6). Pubmedid: 41899279. Pmcid: PMC13026618.
• Bandaru R, Fu H, Zheng H, Liang J, Wang L, Gulati S, Hinrichs BH, Teng M, Zhang B, Kocherginsky M, Lin D, Hildeman DA, Worden FP, Old MO, Dunlap NE, Kaczmar JM, Gillison M, El-Gamal D, Wise-Draper T, Liu Y. Genome-Wide Variations of End Motif in Cell-Free DNA Fragments Distinguish Immunotherapy Responders from Non-Responders in Head and Neck Cancer: A Multi-Institute Prospective Study. medRxiv. 2026 Mar. Pubmedid: 41959799. Pmcid: PMC13060422.
• Teer JK, Ruiz Deya G, Pérez-Mártir SV, Park JY, Oliveras J, Dutil J, Matta J. Genomic Analysis of Puerto Rican Hispanic/Latino Men with Prostate Cancer. Cancers (Basel). 2026 Mar.18(7). Pubmedid: 41976314. Pmcid: PMC13072284.
• Martinez-Planes E, Ramello MC, Fontela MG, Shokri MR, Darville L, Koomen J, Kim Y, Abate-Daga D. C-terminus CD28 phosphorylation (Y218) modulates IL-2 secretion and antitumor effect of CAR-T cells. bioRxiv. 2026 Feb. Pubmedid: 41659581. Pmcid: PMC12874040.
• Tjader NP, Ramroop J, Gandhi T, Dauch C, Meadows O, Stevens P, Pearlman R, Hampel H, Aglago EK, Berndt SI, Bloomer A, Brenner H, Buchanan DD, Campbell PT, Cao Y, Chan AT, Cheng I, Dimou N, Drew DA, French AJ, Georgeson P, Giannakis M, Giles GG, Gomez M, Gruber SB, Hoffmeister M, Huang WY, Hullar MAJ, Huyghe JR, Loroña N, Moreno V, Newton CC, Nowak JA, Obón-Santacana M, Ogino S, Pellatt A, Peoples AR, Permuth JB, Schmit SL, Schoen RE, Siegel EM, Steinfelder RS, Sun W, Teer JK, Thomas CE, Trinh QM, Tsilidis K, Ugai T, Um CY, Van Guelpen B, Zaidi SH, Figueiredo J, Peters U, Phipps AI, McElroy JP, Toland AE. Association of germline variants with KRAS-mutation status in colorectal cancer. Sci Rep. 2026 Feb.16(1). Pubmedid: 41688657. Pmcid: PMC12982500.
• Soyano Muller AE, Goodridge DN, Mo Q, Whiting J, Khakpour N, Lee MC, Laronga C, Armaghani AJ, Han H, Soliman H, Costa R, Loftus L, Hoover SJ, Kiluk JV, Jameel Z, Czerniecki BJ, Khong HT. Neoadjuvant therapy with an aromatase inhibitor and durvalumab in postmenopausal patients with hormone receptor-positive breast cancer. Breast Cancer Res Treat. 2026 Feb.216(1):11. Pubmedid: 41697438.
• Reblin M, Sutton SK, Choi H, Witte D, Wells KJ, Zebrack BJ, Forsyth P, Byrne MM. The CARING intervention for neuro-oncology family caregivers: Primary outcomes from an abbreviated randomized controlled trial. Neurooncol Pract. 2026 Feb.13(1):206-216. Pubmedid: 41798126. Pmcid: PMC12965648.
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• Chaudhary R, Moorhead G, Park R, Li J, Schell MJ, Song X, Tan A, Slebos RJC, Biernacki MI, Freeman SS, Thatikonda S, Meshkovska Y, Hernandez-Prera J, Kirtane K, Guevara-Patino JA, Amelio AL, Rocco JW, Danysh BP, Bonomi M, Saba NF, Haradhvala NJ, Getz G, Chung CH. Long-term Survival and Molecular Biomarker Evaluation of a Phase II Cetuximab and Nivolumab Clinical Trial in Recurrent/Metastatic Head and Neck Cancer. Clin Cancer Res. 2026 Feb.32(3):501-515. Pubmedid: 41117857. Pmcid: PMC12667737.
• Maura F, Bergsagel PL, Ziccheddu B, Kumar S, Maclachlan K, Derkach A, Garces JJ, Firestone R, Braggio E, Asmann Y, Durante M, Diamond BT, Papadimitriou M, Hultcrantz M, Marella A, Castellano G, Maeda A, Lionetti M, Matera A, Pioggia S, Da Vià MC, de Magistris C, Leongamornlert D, DeAvila D, Sudalagunta PR, Canevarolo RR, Siegel EM, Agius P, Teer J, McPherson A, Yamashita Y, Silva AS, Blaney P, Baz R, Patel KK, Campbell P, Morgan G, Fonseca R, Landgren O, Orlowski RZ, Shain KH, Bolli N, Usmani S, Rajkumar SV. Genomics Define Malignant Transformation in Myeloma Precursor Conditions. J Clin Oncol. 2026 Jan.44(3):188-199. Pubmedid: 41061199. Pmcid: PMC12614327.
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• Drobes DJ, Sutton SK, Conn MR, Brandon TH, Yang MJ, Sawyer LE, Hatsukami DK, Donny EC, Simmons VN. Very low nicotine content cigarettes for smoking cessation: Examining a facilitated extinction approach and dosing schedule. Drug Alcohol Depend. 2026 Jan.278:112971. Pubmedid: 41314054. Pmcid: PMC12778942.
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• Shepard A, Lester DK, Troutman S, Hoxha S, Khaled WT, Smith ESJ, Park TJ, Buffenstein R, Du D, Teng M, Dengler-Crish CM, Tsai KY, Flores ER, Ventura A, Kissil JL. An Autochthonous Model of Lung Cancer Identifies Requirements for Cellular Transformation in the Naked Mole Rat. Cancer Discov. 2026 Jan.16(1):35-45. Pubmedid: 40920097. Pmcid: PMC12486303.
• Meads MB, Zhao X, Noyes DR, Sudalagunta P, Achille A, Zhang C, Renatino Canevarolo R, Silva M, Magaletti D, DeAvila D, Toska S, Oates A, Lastorino D, Idiaquez DW, Song J, Sansil S, Yoder SJ, Grajales-Cruz AF, Blue BJ, Freeman CL, Kim J, Alsina M, Brayer J, Siqueira Silva A, Song X, Shain KH, Baz RC. Target antigen and plasma cell phenotype are critical factors for sensitivity to response-adapted daratumumab therapy. Blood. 2026 Jan.147(5):497-512. Pubmedid: 40983035.
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• Obermayer A, Davis J, Talada DP, Teng M, Eschrich S, Yin V, Spakowicz D, Chatterjee D, Rounbehler RJ, Churchman ML, Tarhini AA, Wang X, Gupta S, Markowitz J, Goecks J, Li R, Rodrigues Pessoa R, Manley BJ, Tan AC, Grass GD, Chen DT, Shaw TI. ShinyEvents: harmonizing longitudinal data for real-world survival estimation. NPJ Precis Oncol. 2026 Jan.10(1):54. Pubmedid: 41526666. Pmcid: PMC12877126.
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• Brohl AS, Sondak VK, Wuthrick EJ, Kim Y, Eroglu Z, Markowitz J, Tarhini AA, Fan W, Martin J, Sneed L, Perez MC, Sarnaik A, Harrington M, Neves RI, Gonzalez RJ, Cruse CW, Zager JS, Tsai KY, Khushalani NI. Neoadjuvant lenvatinib plus pembrolizumab in Merkel cell carcinoma: an investigator-initiated, open-label phase II trial. J Immunother Cancer. 2026 Jan.14(1). Pubmedid: 41534900. Pmcid: PMC12815050.
• Fazili A, Gullapalli K, Roman Souza G, Hatoum F, Miller J, Kim Y, Whiting J, Johnson JS, Dhillon J, Nguyen J, Segura CM, Spiess PE, Chahoud J. Geospatial and Cell Density Analysis Using Multiplex Immunofluorescence Reveals an Important Role of Clustering Patterns of Immunosuppressive Macrophages in Survival Outcomes of Penile Squamous Cell Carcinoma. Cancers (Basel). 2026 Jan.18(2). Pubmedid: 41595176. Pmcid: PMC12839248.
• Carson TL, Llanos AAM, Fleming K, Pittman S, Pena A, Henderson J, Doerr V, Cooper AJ, Mallory M, Sutton S, Jim HSL. Rationale and study protocol for a pilot study to determine the feasibility and acceptability of a tailored stress management enhanced behavioral weight loss intervention for Black breast cancer survivors with obesity. Contemp Clin Trials. 2025 Dec.159:108113. Pubmedid: 41135815.
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• Kumar NB, Bahl S, Lemay D, Dhillon J, Poch M, Manley B, Li R, Pow-Sang J, Yu A, Whiting J, Schell MJ. Nutritional intake of ω-3 fatty acid intake and clinical grade of prostate cancer. Cancer Epidemiol. 2025 Dec.99:102959. Pubmedid: 41223508.
• Xu X, Jarajapu V, Chadourne M, Soto-Vargas Z, Ochoa-Rios SL, Jasani N, Wang K, Mecozzi N, Yao J, Yu X, Karreth FA. FRA1 drives melanoma metastasis through an actionable transcriptional network. Oncogene. 2025 Dec.44(50):4895-4909. Pubmedid: 41286309. Pmcid: PMC12669035.
• Di Meo F, Albano F, Cesarano A, Wang Y, Kale B, Shain K, Silva A, Kurihara N, Tenshin H, Jellyman D, Song X, Ghaffari S, Mesa H, Creelan B, Freeman C, Zhao X, Meads MB, Rodriguez PC, Marino S, Locke F, Hwu P, Roodman D, Mansilla-Soto J, Perna F. Developing SEMA4A-directed CAR T cells to overcome low BCMA antigen density in multiple myeloma. Cancer Cell. 2025 Dec.43(12):2298-2310.e6. Pubmedid: 41072416. Pmcid: PMC12614569.
• Kazemian E, Mo Q, Matejcic M, Tsai YY, Sobieski D, Li X, Hoogland AI, Crowder SL, Gonzalez BD, Oswald LB, Sleight AG, Nguyen N, Loroña NC, Damerell V, Komrokji KR, Mooney K, Playdon MC, Ulrich CM, Li CI, Shibata D, Toriola AT, Ose J, Peoples AR, Hardikar S, Kahlert C, Siegel EM, Bower JE, Schmit SL, Gigic B, Jim HSL, Figueiredo JC. Genetic predisposition to persistent fatigue after a diagnosis of colorectal cancer. J Natl Cancer Inst. 2025 Dec.117(12):2513-2525. Pubmedid: 40889272. Pmcid: PMC12682389.
• Parker NH, Ramos JD, Tarhini AA, Schell MJ, Egan KM, Kanetsky PA. A Retrospective Cohort Study of Physical Activity and Survival in Patients Treated with Immune Checkpoint Inhibitors. Cancer Epidemiol Biomarkers Prev. 2025 Dec.34(12):2219-2227. Pubmedid: 40971247. Pmcid: PMC12579459.
• Nekrutenko A, Callan D, Van Den Beek M, Baker D, Rogers D, Guerler A, Chilton J, Clawson H, Cain S, O'Meara T, Beavers K, Schatz M, Haeussler M, Gruning B, Goecks J, Pond SK. Standardizing RNA-seq Analysis of Fungal Pathogens Using BRC-Analytics and Agentic AI: A Candidozyma auris Case Study. bioRxiv. 2025 Dec. Pubmedid: 41509213. Pmcid: PMC12776552.
• Yamoah K, Trivedi P, Awasthi S, Grass GD, Torres-Roca J, Johnstone PA, Dhillon J, Park JY, Davicioni E, Hakansson A, Liu Y, Fink AK, Katende E, Smith R, Putney R, Poch M, Li R, Manley B, Fernandez D, Gage K, Ferguson K, Lu-Yao G, Kim Y, Katsoulakis E, Leone A, Vapiwala N, Deville C, Rebbeck TR, Dicker AP, Kelly W, Yin V, Burri RJ, Ercole CE, Pow-Sang J. A Prospective Validation of the Decipher Genomic Classifier in Men With Early Localized Prostate Cancer: The VANDAAM Study. J Natl Compr Canc Ne. 2025 Dec.24(1). Pubmedid: 41671436.
• Colin-Leitzinger C, Tang YH, Teng M, Gillis N. Ancestry-dependent patterns of somatic mosaicism and clonal hematopoiesis mutations in over 125,000 individuals reveal distinct cancer associations. Hum Genomics. 2025 Dec.19(1):142. Pubmedid: 41331781. Pmcid: PMC12673770.
• Kim DW, Kim RD, Jimenez MM, Kim Y, Mehta R. A phase II study of trifluridine/tipiracil in combination with ramucirumab in advanced, refractory gastric, or gastroesophageal junction adenocarcinomas. Oncologist. 2025 Dec.30(12). Pubmedid: 41335458. Pmcid: PMC12681051.
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