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Robin  Park

Robin Park, MD

Program: Head and Neck Oncology

Research Program: Immuno-Oncology Program

  • Overview

    Dr. Park's research theme includes improving patient outcomes by developing effective novel immunotherapies and biomarkers.

    Associations

    • Head and Neck-Endocrine Oncology
    • Immuno-Oncology Program
  • Research Interest

    Dr. Park's research interests are in the development of effective treatment biomarkers and novel therapies with a focus on early-phase drug development.

  • Participating Trials

    Clinical Trial 23645
    PHASE 1 DOSE ESCALATION AND EXPANSION STUDY OF XB628 AS A SINGLE AGENT AND IN COMBINATION WITH ZANZALINTINIB IN PARTICIPANTS WITH ADVANCED OR METASTATIC SOLID TUMORS
    Condition: Multiple
    Intervention: XB628 (); Zanzalintinib ()
    Status: Open

    Clinical Trial 23647
    A Phase 1/2, Open-label, Global, Multicenter, Dose-Escalation and Dose-Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of PYX-201 in Combination with Pembrolizumab in Participants with Advanced Solid Tumors
    Condition: Head & Neck
    Intervention: PYX-201 (); Pembrolizumab (Keytruda)
    Status: Open

    Clinical Trial 23829
    A Phase 1/2 First-in-Human, Open-Label, Dose Escalation and Expansion Trial of TAK-505 Monotherapy in Participants with Unresectable Locally Advanced or Metastatic Solid Tumors
    Condition: Multiple
    Intervention: TAK-505 ()
    Status: Open

    Clinical Trial 23965
    A Phase I, Open-Label, Multinational, Multicenter, Dose Escalation and Expansion Study of BH3120, as a Single agent and in Combination with pembrolizumab, in Patients with Advanced or Metastatic Solid Tumors
    Condition: Multiple
    Intervention: BH3120 (); Pembrolizumab (Keytruda)
    Status: Open

    Clinical Trial 23993
    A Phase 1a/1b, Open-label, Dose-escalation, and Dose-expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of IMGS-001 in Patients with Relapsed or Refractory Advanced Solid Tumors
    Condition: Multiple
    Intervention: IMGS-001 ()
    Status: Open

    If you believe you are eligible for one of these trials or studies, please call
    813-745-6100 or toll-free 1-800-679-0775.

  • Publications

    • Basharat A, Mannan MS, Shabbir MR, Khan MW, Basit T, Park R, Chadha J, Shahzad M. Transient PSA Suppression Without Survival Benefit: Real-World Comparative Effectiveness of Cabazitaxel Plus Carboplatin in Metastatic Castration-Resistant Prostate Cancer (mCRPC). Clin Genitourin Cancer. 2026 Jul.24(6):102625. Pubmedid: 42556088.
    • Chaudhary R, Moorhead G, Park R, Li J, Schell MJ, Song X, Tan A, Slebos RJC, Biernacki MI, Freeman SS, Thatikonda S, Meshkovska Y, Hernandez-Prera J, Kirtane K, Guevara-Patino JA, Amelio AL, Rocco JW, Danysh BP, Bonomi M, Saba NF, Haradhvala NJ, Getz G, Chung CH. Long-term Survival and Molecular Biomarker Evaluation of a Phase II Cetuximab and Nivolumab Clinical Trial in Recurrent/Metastatic Head and Neck Cancer. Clin Cancer Res. 2026 Feb.32(3):501-515. Pubmedid: 41117857. Pmcid: PMC12667737.
    • Park R, Rind F, Kristoff T, Li J, Schell M, Slebos RJC, Thatikonda S, Chaudhary R, Biernacki MI, Meshkovska Y, Kaldas D, Kim HS, Farinhas J, Hernandez-Prera J, Kirtane K, Hall MS, Amelio AL, Rocco JW, Bhateja P, Steuer C, Bonomi M, Saba NF, Chung CH. Evaluation of Neutrophil to Lymphocyte Ratio in Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma Treated With a Combination of Cetuximab and Nivolumab in a Phase II Clinical Trial. Am J Clin Oncol. 2026 Apr.49(4):176-187. Pubmedid: 40905435. Pmcid: PMC13011960.
    • Lee WJ, Asghar MS, Park R, Won SH, Shahzad M, Shimshak T. Externally Validated Machine Learning Models for 30-/90-/180-Day Unplanned Readmission After Head and Neck Cancer Hospitalizations in the United States. JCO Clin Cancer Inform. 2026 Apr.10(2):e2500335. Pubmedid: 42284547. Pmcid: PMC13268123.
    • Yu J, Park R, Miao R, Imanirad I, Shahzad M, Laborde JM, Knepper TC, Walko CM, Kim R. Blood Tumor Mutational Burden Alone Is Not a Good Predictive Biomarker for Response to Immune Checkpoint Inhibitors in Patients With Gastrointestinal Tumors. J Immunother. 2024 Nov.47(9):378-383. Pubmedid: 39012081.
    • Shahzad M, Khalid MF, Amin MK, Basharat A, Ammad-Ud-Din M, Park R, Anwar I, Faisal MS, Jaglal M. Geographic and Racial Disparities in Chimeric Antigen Receptor-T Cells and Bispecific Antibodies Trials Access for Diffuse Large B-Cell Lymphoma. Clin Lymphoma Myeloma Leuk. 2024 May.24(5):316-322. Pubmedid: 38342727.
    • Park R, Yu J, Shahzad M, Lee S, Ji JD. The immune regulatory function of B7-H3 in malignancy: spotlight on the IFN-STAT1 axis and regulation of tumor-associated macrophages. Immunol Res. 2024 Aug.72(4):526-537. Pubmedid: 38265550.

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